Cyclin G2 is a target molecule of Cn/NFATc2 in follicular keratinocytes. by Atsushi Fujimura (227683)

“…<p>(A) The microarray analysis identified 24 genes that showed down-regulated expression in PHK cells treated with either 11R-VIVIT or CsA; <i>ccng2</i> (cyclin G2) expression showed the greatest decrease after Cn/NFAT inhibition. …”

ASLV-A pseudovirus fusion with endosomes results in iCherry release and YFP dequenching. by Sergi Padilla-Parra (166100)

“…<p>(A, C) Micrographs are showing consecutive snapshots of ASLV-A pseudovirus entry into CV1 cells expressing TVA950. …”

Potential Role of Estrogen Receptor Beta as a Tumor Suppressor of Epithelial Ovarian Cancer by Carine Bossard (138058)

“…Previous studies have shown that Estrogen-receptor beta (ERβ) levels decreased along with ovarian carcinogenesis. Here, we present evidence that reintroduction of ERβ in BG-1 epithelial ovarian cancer cells, which express ERα, leads <em>in vitro</em> to a decrease of basal and estradiol-promoted cell proliferation. …”

Temporal Sensitivity of Protein Kinase A Activation in Late-Phase Long Term Potentiation by MyungSook Kim (65534)

“…Examination of CaMKII reveals that its temporal sensitivity is opposite that of PKA, suggesting that PKA is required after spaced stimulation to compensate for a decrease in CaMKII. In addition to explaining the temporal sensitivity of PKA, these simulations suggest that the use of several kinases for memory storage allows each to respond optimally to different temporal patterns.…”

A partial genome assembly of the miniature parasitoid wasp, <i>Megaphragma amalphitanum</i> by Fedor S. Sharko (6575339)

“…<i>amalphitanum</i> genomic data reveal certain features that may be linked to the unusual biological properties of this organism, miniaturization is not associated with a large decrease in genome complexity.</p></div>…”

Modulation of HS α4β2 receptors with a low concentration of arecoline. by Roger L. Papke (685990)

“…<p>(A) Partial agonists for α4β2 nAChR such as varenicline and cytisine [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140907#pone.0140907.ref035" target="_blank">35</a>] modulate the sensitivity of the receptors to the endogenous activator ACh through pre-desensitization for prolonged periods, even when present at very low concentrations. …”

SIRT1 preserves dendritic integrity in hippocampal neurons challenged with Aβ fibrils. by Juan F. Codocedo (304388)

“…Treatment with Aβ fibrils significantly decrease the number of intersection at 28–110 µm from the soma compared with GFP transfected neurons (p<0,01 at 28–100 µm). …”

Polymer blend: a new approach for eliminating curing effect of aqueous dispersion coatings by Nasir Abbas (312677)

“…Propranolol HCl 10% w/w was layered onto sugar cores using 5% w/w HPMC as a binder. Drug-layered-cores were coated either with pure or blends of Aquacoat® ECD: Eudragit® NE 30D in a fluidized bed coater to obtain 20% w/w coating level. …”

Insights into Transient Dynamics of Bacteria-Laden Liquid Bridges by Kush Kumar Dewangan (20909777)

“…We show that for all confinement distances the volume regression is linear on normalizing both volume and time as in the case of a pure sessile drop. …”

Genetic characterization of <i>Mycoplasma pneumoniae</i> isolated in Osaka between 2011 and 2017: Decreased detection rate of macrolide-resistance and increase of <i>p1</i> gene ty... by Chihiro Katsukawa (6264050)

“…The remaining strain with an irregular typing pattern had a large deletion in the <i>p1</i> operon.</p></div>…”

Common organizational patterns of connectivity modes. by Justine Y. Hansen (17041502)

“…Exponential equations or Spearman correlation coefficients are shown depending on whether the relationship is better fit by an exponential or linear function. Similar relationships with geodesic distance are shown in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002314#pbio.3002314.s002" target="_blank">S2 Fig</a>. …”

Lateral movement of the saddle relative to the equine spine in rising and sitting trot on a treadmill by A. Byström (5533262)

“…<div><p>Saddle slip, defined as a progressive lateral displacement of the saddle during ridden exercise, has recently been given attention in the scientific press as a potential sign of lameness. …”

IL-5 responses to larval <i>Strongyloides stercoralis</i> antigens are decreased in patients with strongyloidiasis and HTLV-1 co-infection (n = 13) compared to HTLV-1 negative subj... by Martin Montes (372264)

Supplementary Material for: Epidemiology of Transthyretin Familial Amyloid Polyneuropathy in Portugal: A Nationwide Study by Inês M. (5678270)

“…<b><i>Results:</i></b> Over 2010–2016 period, mean incidence rates was 0.87/100,000 (95% CI 0.68–1.10) corresponding to 71 new patients yearly, that has decreased 31% in the last 7 years. …”

Validated registry of pre-dialysis chronic kidney disease: description of a large cohort by Rosalia Maria Nunes Henriques Huaira (5187425)

“…The percentage of users with a decline in the glomerular filtration rate was 33.7%. …”

Lutein as a functional ingredient in sheep milk yogurt: development, characterization and extraction recovery by Raphael Ferreira de BARROS (10463278)

“…Some differences (P < 0.05) in the same treatment occurred over time, tending to decrease lutein recovery. For all treatments, up to the end of storage, the final amount of lutein characterized the product as a nutritional source of this element. …”

Spotlight on Mitochondrial Health: A Trailblazing Fluorescent Tool for Cancer Detection and Surgical Guidance by Wei Zhang (405)

“…The mitochondrial autophagy process of disease-related cells is usually accompanied by a decrease in polarity and pH, and the fluorescence sensing effects caused by these two factors are usually contradictory. …”

Dissipative Self-Assembly of Patchy Particles under Nonequilibrium Drive: A Computational Study by Shubhadeep Nag (18888287)

“…Utilizing extensive Monte Carlo (MC) and Molecular Dynamics (MD) simulations, we provide insight into the effects of external forces that mirror natural and chemical processes on the assembly rates and the stability of the resulting assemblies comprising 8, 10, and 13 patchy particles. Implemented by a favorable bond-promoting drive in MC or a pulsed square wave potential in MD, our simulations reveal the role these external drives play in accelerating assembly kinetics and enhancing structural stability, evidenced by a decrease in the time to first assembly and an increase in the duration the system remains in an assembled state. …”

Hypoxia-inducible factor-1 alpha as a therapeutic target for primary effusion lymphoma by Prabha Shrestha (776391)

“…Moreover, HIF-1α knockdown led to a decrease in the expression of various KSHV latent genes, including LANA, vCyclin, kaposin, and miRNAs, under both normoxic and hypoxic conditions. …”

Illustration depicting how membrane proteins might incorporate into LCP in a PLI experiment. by Ellen Wallace (207446)

“…According to this model, productive incorporation from the micellar phase occurs if k₁>k₂ and interfacial concentration occurs only if diffusion is slow as compared to the incorporation step (k₁>k₃).Detergents have been shown to dramatically decrease the curvature of monoolein-based LCP <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0024488#pone.0024488-Briggs1" target="_blank">[30]</a>, likely resulting in altered mesophase arragements of protruding bilayers consisting of monoolein (green and gray) and detergent molecules (blue and gray; in our case the detergent is LDAO) that serve as portals for membrane protein incorporation. …”