DataSheet1_Switching Among Biosimilars: A Review of Clinical Evidence.docx by Eleonora Allocati (9980204)

“…This study summarizes evidence on switching between biosimilars for which there are concerns to provide future guidance. A systematic search (MEDLINE, Embase, and Cochrane Library) for studies on anti-TNF agents, assessing clinical efficacy and safety of biosimilar-to-biosimilar switch in chronic inflammatory diseases, was performed. …”

Mechanism of Mitochondrial Transcription Factor A Attenuation of CpG-Induced Antibody Production by Christopher S. Malarkey (2826386)

“…These data suggest that TFAM alters the free concentration of the CpG available to stimulate B cells by sequestering this ODN in a TFAM-CpG complex. Thus, TFAM has the potential to decrease the pathogenic consequences of exposure to natural CpG-like hypomethylated DNA <i>in vivo</i>, as well as such as that found in traumatic injury, infection, autoimmune disease and during pregnancy.…”

Data for Circadian activity in a folivorous ground squirrel: questions of entrainment and weather effects by Nina Vasilieva (6816554)

“…All squirrels exhibited a decrease in both motor and aboveground activity duration as the season progressed. …”

Is thermal stability a factor that influences environmental heterogeneity and phytoplankton distribution in tropical lakes? by Luciana Gomes Barbosa (5139065)

“…Methods Monthly measurements were performed over a five-year period in the vertical profile of a warm monomitic shallow lake (Lago Carioca) and in a deep and meromictic (Lake Dom Helvécio). …”

Dissipative Self-Assembly of Patchy Particles under Nonequilibrium Drive: A Computational Study by Shubhadeep Nag (18888287)

“…Utilizing extensive Monte Carlo (MC) and Molecular Dynamics (MD) simulations, we provide insight into the effects of external forces that mirror natural and chemical processes on the assembly rates and the stability of the resulting assemblies comprising 8, 10, and 13 patchy particles. Implemented by a favorable bond-promoting drive in MC or a pulsed square wave potential in MD, our simulations reveal the role these external drives play in accelerating assembly kinetics and enhancing structural stability, evidenced by a decrease in the time to first assembly and an increase in the duration the system remains in an assembled state. …”

The similarity metric as a function of noise shows increased order in the intermediate noise regime. by Madeline Galbraith (9205218)

“…The trends seen in the similarity metric mimic those exhibited by the correct contacts as a function of white or shot noise. While the similarity metric drops below S = 1 for the checkerboard initial condition more quickly than the fraction of correct contacts changes (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010306#pcbi.1010306.g004" target="_blank">Fig 4</a>), the steady decrease in the similarity metric is representative of the modulation and a loss of separation in the Delta values of the Sender and Receiver cell (see again <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010306#pcbi.1010306.s010" target="_blank">S7 Fig</a>).…”

Table_1_Inadequate Bioavailability of Intramuscular Epinephrine in a Neonatal Asphyxia Model.DOCX by Sara K. Berkelhamer (4232437)

“…Background<p>Over half a million newborn deaths are attributed to intrapartum related events annually, the majority of which occur in low resource settings. …”

Dissipative Self-Assembly of Patchy Particles under Nonequilibrium Drive: A Computational Study by Shubhadeep Nag (18888287)

“…Utilizing extensive Monte Carlo (MC) and Molecular Dynamics (MD) simulations, we provide insight into the effects of external forces that mirror natural and chemical processes on the assembly rates and the stability of the resulting assemblies comprising 8, 10, and 13 patchy particles. Implemented by a favorable bond-promoting drive in MC or a pulsed square wave potential in MD, our simulations reveal the role these external drives play in accelerating assembly kinetics and enhancing structural stability, evidenced by a decrease in the time to first assembly and an increase in the duration the system remains in an assembled state. …”

Dissipative Self-Assembly of Patchy Particles under Nonequilibrium Drive: A Computational Study by Shubhadeep Nag (18888287)

“…Utilizing extensive Monte Carlo (MC) and Molecular Dynamics (MD) simulations, we provide insight into the effects of external forces that mirror natural and chemical processes on the assembly rates and the stability of the resulting assemblies comprising 8, 10, and 13 patchy particles. Implemented by a favorable bond-promoting drive in MC or a pulsed square wave potential in MD, our simulations reveal the role these external drives play in accelerating assembly kinetics and enhancing structural stability, evidenced by a decrease in the time to first assembly and an increase in the duration the system remains in an assembled state. …”

Dissipative Self-Assembly of Patchy Particles under Nonequilibrium Drive: A Computational Study by Shubhadeep Nag (18888287)

“…Utilizing extensive Monte Carlo (MC) and Molecular Dynamics (MD) simulations, we provide insight into the effects of external forces that mirror natural and chemical processes on the assembly rates and the stability of the resulting assemblies comprising 8, 10, and 13 patchy particles. Implemented by a favorable bond-promoting drive in MC or a pulsed square wave potential in MD, our simulations reveal the role these external drives play in accelerating assembly kinetics and enhancing structural stability, evidenced by a decrease in the time to first assembly and an increase in the duration the system remains in an assembled state. …”

Spotlight on Mitochondrial Health: A Trailblazing Fluorescent Tool for Cancer Detection and Surgical Guidance by Wei Zhang (405)

“…The mitochondrial autophagy process of disease-related cells is usually accompanied by a decrease in polarity and pH, and the fluorescence sensing effects caused by these two factors are usually contradictory. …”

Dissipative Self-Assembly of Patchy Particles under Nonequilibrium Drive: A Computational Study by Shubhadeep Nag (18888287)

“…Utilizing extensive Monte Carlo (MC) and Molecular Dynamics (MD) simulations, we provide insight into the effects of external forces that mirror natural and chemical processes on the assembly rates and the stability of the resulting assemblies comprising 8, 10, and 13 patchy particles. Implemented by a favorable bond-promoting drive in MC or a pulsed square wave potential in MD, our simulations reveal the role these external drives play in accelerating assembly kinetics and enhancing structural stability, evidenced by a decrease in the time to first assembly and an increase in the duration the system remains in an assembled state. …”

Spotlight on Mitochondrial Health: A Trailblazing Fluorescent Tool for Cancer Detection and Surgical Guidance by Wei Zhang (405)

“…The mitochondrial autophagy process of disease-related cells is usually accompanied by a decrease in polarity and pH, and the fluorescence sensing effects caused by these two factors are usually contradictory. …”

<b>Human disturbance alters the foraging and spatiotemporal activity of a large carnivore</b> by Gonzalo Barceló (10117075)

“…Responses to human disturbance were generally consistent across sites, with pumas adjusting their temporal, spatial, and foraging axes to decrease encounters with humans. Our results suggest that human-disturbed landscapes across regions alter the primary niche axes of pumas to construct a new realized niche in human landscapes, which may have important consequences for their ecological interactions and the functional role of this large carnivore.…”

Unravelling CO Activation on Flat and Stepped Co Surfaces: A Molecular Orbital Analysis by Rozemarijn D.E. Krösschell (18604265)

“…Structure sensitivity in heterogeneous catalysis dictates the overall activity and selectivity of a catalyst whose origins lie in the atomic configurations of the active sites. …”

Is a sequence of tests during urethral pressure profilometry correlated with symptoms assessment in women? by Françoise A. Valentini (12832132)

“…<div><p>IntroductionOur purpose was, applying a strictly defined protocol for urethral profilometry, 1) to test the repeatability of same session rest maximum urethral closure pressure (MUCP) and 2) to search for correlation between women complaint and the changes in MUCP value (rest and dynamic tests).Materials and MethodsA population of 140 consecutive women referred for evaluation of lower urinary tract dysfunction was stratified in 4 groups according with the urinary symptoms: stress, urge, mixed incontinence and continent and in each group in 3 age groups (young, middle age and old). …”

A summarized schematic of the proliferation and migration of the epidermal basal cells, based on our results. by Sari Ipponjima (3133578)

“…<p>(<b>A</b>) Schematic of parallel and oblique division. …”

Single Molecule Nanospectroscopy Visualizes Proton-Transfer Processes within a Zeolite Crystal by Zoran Ristanović (1359162)

“…Interestingly, replacing <i>n</i>-heptane with 1-butanol as a solvent led to a reactivity decrease of several orders and shorter survival times of fluorescent products due to the strong chemisorption of 1-butanol onto the Brønsted acid sites. …”

The Spastic Paraplegia-Associated Phospholipase DDHD1 Is a Primary Brain Phosphatidylinositol Lipase by Jordon M. Inloes (4717320)

“…Here we use a combination of untargeted and targeted metabolomics to compare the lipid content of brain tissue from DDHD1^+/+ and DDHD1^–/– mice, revealing that DDHD1 inactivation causes a substantial decrease in the level of polyunsaturated lysophosphatidylinositol (LPI) lipids and a corresponding increase in the level of phosphatidylinositol (PI) lipids. …”

Feedback Inhibition in the PhoQ/PhoP Signaling System by a Membrane Peptide by Andrew M. Lippa (255368)

“…Interestingly, we found that elimination of MgrB-mediated feedback did not have a significant effect on the kinetics of reporter protein production and did not decrease the variability in expression among cells. …”