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47581
A novel approach in mucoadhesive drug delivery system to improve zidovudine intestinal permeability
Published 2022“…SDs allowed drug dissolution to occur in a controlled manner. HPMCP decreased the dissolution rates in the acid medium. …”
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47582
A role for the RNAPII-CTD and Cdk8 in Ty1 gene expression regulation.
Published 2015“…Truncation of the RNAPII-CTD alone resulted in increased Cdk8 recruitment to Ty1 elements and increased S<sub>5</sub> phosphorylation levels, a key mark for promoter clearance. The increased S<sub>5</sub> phosphorylation levels in the <i>rpb1-CTD11</i> mutant were direct or indirectly dependent on Cdk8, thus in the <i>rpb1-CTD11 cdk8Δ</i> double mutant S<sub>5</sub> phosphorylation levels were normalized resulting in decreased levels of promoter clearance.…”
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47583
SOURCES OF HEAT REJECTION IN A HDDI DIESEL ENGINE AND METHODS TO IMPROVE THERMAL EFFICIENCY
Published 2019“…By studying test cell data of heat rejection on a production Cummins ISX engine and using the data to calibrate an engine model for the simulation software GT-Suite, heat rejection values and the components which transfer the energy are exposed. …”
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47584
On modelling of resiliency events using building performance simulation: a multi-objective approach
Published 2022“…Resiliency indicators are improved by two times and the payback of upgrade packages is decreased to 14 years for a single outage event.</p>…”
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47585
<b>NWB2023_A preliminary exploration on the dynamics of international scientific mobility</b>
Published 2023“…With the help of large-scale datasets to capture longitudinal, country-level patterns of migrations in science, this paper outlines the evolution of scientific mobility over the past 100 years. There has been a dramatic growth in scientific mobility both at the global and regional levels. …”
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47586
Current Monitoring in a Microchannel with Repeated Constrictions for Accurate Detection of Sample Location in Isotachophoresis
Published 2015“…We present a new method for accurate detection of sample location in peak mode isotachophoresis (ITP). …”
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47587
Fcn2.m from Dynamics and locomotion of flexible foils in a frictional environment.
Published 2018“…When the foil is oscillated by heaving at one end but is not free to locomote, the dynamics change from periodic to non-periodic and chaotic as the heaving amplitude increases or the bending rigidity decreases. For friction coefficients lying in a certain range, the transition passes through a sequence of <i>N</i>-periodic and asymmetric states before reaching chaotic dynamics. …”
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47588
A New Genotype Imputation Method with Tolerance to High Missing Rate and Rare Variants
Published 2014“…For minor allele, the accuracy of BEAGLE and fastPHASE decreased to −0.1 and 0.03, while iBLUP still had an accuracy of 0.61.We implemented the algorithm in a publicly available software package also named iBLUP. …”
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47589
Relative localization of TAPP2, utrophin and F-actin upon chemokine stimulation. A.
Published 2013“…</b> Relative localization of TAPP2 versus F-actin was visualized and quantified using similar methods as in A (5 experiments). A significant reduction in the overall colocalization of TAPP2 and F-actin was seen in SDF-1 stimulated cells (Student <i>t</i> test: ***p<0.001). …”
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47590
A subset of octopaminergic neurons that promotes feeding initiation in <i>Drosophila melanogaster</i>
Published 2018“…Moreover, RNAi knockdown of a specific class of octopamine receptor, OAMB, selectively in sugar-sensing gustatory neurons decreased the behavioral response to sucrose. …”
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47591
Current Monitoring in a Microchannel with Repeated Constrictions for Accurate Detection of Sample Location in Isotachophoresis
Published 2015“…We present a new method for accurate detection of sample location in peak mode isotachophoresis (ITP). …”
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47592
Reducing angle of coverage increases fiber recruitment in a model of the rat vagus nerve.
Published 2019“…<p>a) Recruitment curves generated using a cuff with a 1 mm inner diameter, but with the nerve positioned at next to the contacts. …”
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47593
Associations of genetically determined iron status across the phenome: A mendelian randomization study
Published 2019“…After correcting for multiple testing, the 3 genetic instruments for systemic iron status demonstrated consistent evidence of a causal effect of higher iron status on decreasing risk of traits related to anemia (iron deficiency anemia: odds ratio [OR] scaled to a standard deviation [SD] increase in genetically determined serum iron levels 0.72, 95% confidence interval [CI] 0.64–0.81, <i>P</i> = 4 × 10<sup>−8</sup>) and hypercholesterolemia (hypercholesterolemia: OR 0.88, 95% CI 0.83–0.93, <i>P</i> = 2 × 10<sup>−5</sup>) and increasing risk of traits related to infection of the skin and related structures (cellulitis and abscess of the leg: OR 1.25, 95% CI 1.10–1.42, <i>P</i> = 6 × 10<sup>−4</sup>). …”
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47594
Corrosion behavior of API X100 steel material in a hydrogen sulfide environment
Published 2017“…It is noticed that an accumulation of a critical amount of hydrogen in the metal can result in hydrogen-induced crack initiation and propagation. …”
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47595
Critical proportion of ITL as a function of the insecticidal (<i>k</i>), and diversionnary effect ().
Published 2014“…<p>The lines show the combination of values of coverage and insecticidal probability required to achieve <i>R</i><sub>0</sub> = 1, above which <i>R</i><sub>0</sub> will be decreased below 1, for a given diversion probability (). …”
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47596
Pre-clinical interaction of ayahuasca, a brew used in spiritual movements, with morphine and propofol
Published 2018“…<div><p>ABSTRACT Ayahuasca is a beverage with psychoactive properties used in religious and ceremonial rituals by some religious groups. …”
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47597
The electrical activity recorded from a cold thermoreceptor nerve terminal at the corneal surface.
Published 2018“…During heating and cooling the frequency of NTIs was decreased and increased, respectively. <b>C</b>, overlaid traces recorded during stimulation of the ciliary nerves with a train of 25 pulses at 1 Hz. …”
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47598
Retinoic acid is a key signaling hub in the highest ranked network generated by IPA.
Published 2010“…Abbreviations of proteins identified as significantly changed from the mass spectrometry dataset (indicated in green and red) are: GGT1, gamma-glutamyltransferase 1; ACOX1, acyl-Coenzyme A oxidase 1; CYP4B1, cytochrome P450, family 4, subfamily B, polypeptide 1; ADH1C, alcohol dehydrogenase 1C; CANX, calnexin; PAH, phenylalanine hydroxylase; EEF, elongation factor; GSTA5, glutathione S-transferase alpha 5.…”
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47599
Optimization of a cationic liposomal gene delivery system and study of its endocytic pathway
Published 2023“…<div><p>Abstract A cationic liposomal gene delivery system comprising DOTAP, DOPE, and cholesterol was prepared and optimized. …”
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47600
Is dialysis water a safe component for hemodialysis treatment in São Paulo State, Brazil?
Published 2020“…Total coliform was verified at a lower frequency. We highlighted the importance of regular monitoring of dialysis water quality to prevent infections caused by dialytic procedures and to ensure that the water is a safe component of the treatment.…”