Image1_A Role of Caveolae in Trabecular Meshwork Mechanosensing and Contractile Tone.JPEG by Michael L. De Ieso (12254687)

“…Elevation of pMLC levels following Cav1 knockdown occurred in cells on a soft surface (137 ± 7%, n = 24, p < 0.0001), but not on a hard surface (122 ± 17%, n = 12, p = 0.22). …”

Image 7_Atypical bilateral papilledema during the puerperium: a case report.jpeg by Ligang Jiang (5664820)

“…</p>Case report<p>A 28-year-old woman, 3 days post-operative from a cesarean section, presented at the hospital with decreased vision in her right eye. …”

Erythropoietin Levels in Elderly Patients with Anemia of Unknown Etiology by Zachary Gowanlock (2838965)

“…</p><p>Conclusions</p><p>We have shown that erythropoietin levels are inappropriately low in anemia of unknown etiology, even after adjusting for confounders. This suggests that decreased erythropoietin production may play a key role in the pathogenesis of anemia of unknown etiology.…”

Differential reinforcement of two neurons (within a simulated network of 4000 neurons, the two rewarded neurons are denoted as A and B), corresponding to the experimental results s... by Robert Legenstein (243392)

“…The firing rate of neuron A (blue line) increases while it is positively reinforced in the first half of the simulation and decreases in the second half when its spiking is negatively reinforced. …”

<i>Tg</i>G6PDH1, <i>Tg</i>G6PDH2, <i>Tg</i>6PGDH1, <i>Tg</i>RuPE and <i>Tg</i>TAL are dispensable for parasite growth and virulence, while <i>Tg</i>G6PDHs are required for defendin... by Ningbo Xia (13584299)

A Modular Multilevel Voltage-Boosting Marx Pulse-Waveform Generator for Electroporation Applications by Elgenedy M.A.

“…At start up, all the arm's SM capacitors are resonantly charged in parallel from 0 V, simultaneously via directing diodes, to a voltage in excess of the source voltage. After the first pulse delivery, the energy of the SM capacitors decreases due to the generated pulse. …”
Get full text
Get full text

Image3_Artemis inhibition as a therapeutic strategy for acute lymphoblastic leukemia.jpeg by Heather A. Ogana (11774297)

“…<p>As effective therapies for relapse and refractory B-cell acute lymphoblastic leukemia (B-ALL) remain problematic, novel therapeutic strategies are needed. Artemis is a key endonuclease in V(D)J recombination and nonhomologous end joining (NHEJ) of DNA double-strand break (DSB) repair. …”

Metabolic Fingerprints of Altered Brain Growth, Osmoregulation and Neurotransmission in a Rett Syndrome Model by Angèle Viola (30605)

“…This approach provided a “metabolic window” to brain characteristics in <em>Mecp2</em>-null mice (n = 4), revealing (i) the first metabolic evidence of astrocyte involvement in RS (decreased levels of the astrocyte marker, <em>myo</em>-inositol, vs. wild-type mice; p = 0.034); (ii) reduced choline phospholipid turnover in <em>Mecp2</em>-null vs. wild-type mice, implying a diminished potential of cells to grow, paralleled by globally reduced brain size and perturbed osmoregulation; (iii) alterations of the platelet activating factor (PAF) cycle in <em>Mecp2</em>-null mouse brains, where PAF is a bioactive lipid acting on neuronal growth, glutamate exocytosis and other processes; and (iv) changes in glutamine/glutamate ratios (p = 0.034) in <em>Mecp2</em>-null mouse brains potentially indicating altered neurotransmitter recycling.…”

Image_1_A Bibliometric Analysis of Atrophic Gastritis From 2011 to 2021.PNG by Tai Zhang (1398820)

“…Background<p>Atrophic gastritis (AG), which is characterized by a decreased number or disappearance of the glandular structures and secretory dysfunction, is linked to chronically inflamed stomach. …”

Image_4_Efficacy of an environmental enrichment intervention for endometriosis: a pilot study.pdf by Grace De Hoyos (17124586)

“…Introduction<p>We have previously shown that Environmental Enrichment (EE), a multi-modal psychosocial intervention consisting of increased social interaction, novelty, and open spaces, improved disease presentation, anxiety, and immune-related disturbances in the rat model of endometriosis. …”

A Proteomic Approach Identifies Candidate Early Biomarkers to Predict Severe Dengue in Children by Dang My Nhi (2136469)

Table_1_Relationship Between the Pyroptosis Pathway and Epilepsy: A Bioinformatic Analysis.xlsx by Lu Xia (1509745)

“…</p>Methods<p>Weighted gene co-expression network analysis (WGCNA) was used to construct a signed co-expression network from expression data to screen gene sets closely related to epilepsy. …”

Ylide-Substituted Phosphines with a Cyclic Ylide-Backbone: Angle Dependence of the Donor Strength by Julian Löffler (11232988)

“…Density functional theory calculations revealed that the small angle results in an increased s-character of the lone pair at the ylidic carbon atom and leads to a polarization of the C–P bond toward the carbon atom, thus decreasing the electron density at the phosphorus atom. …”

DataSheet1_Mathematical Modeling of a Supramolecular Assembly for Pyrophosphate Sensing.PDF by Fereshteh Emami (11860259)

“…<p>The power of sensing molecules is often characterized in part by determining their thermodynamic/dynamic properties, in particular the binding constant of a guest to a host. In many studies, traditional nonlinear regression analysis has been used to determine the binding constants, which cannot be applied to complex systems and limits the reliability of such calculations. …”

Table_4_Relationship Between the Pyroptosis Pathway and Epilepsy: A Bioinformatic Analysis.docx by Lu Xia (1509745)

“…</p>Methods<p>Weighted gene co-expression network analysis (WGCNA) was used to construct a signed co-expression network from expression data to screen gene sets closely related to epilepsy. …”

Image1_Artemis inhibition as a therapeutic strategy for acute lymphoblastic leukemia.jpg by Heather A. Ogana (11774297)

“…<p>As effective therapies for relapse and refractory B-cell acute lymphoblastic leukemia (B-ALL) remain problematic, novel therapeutic strategies are needed. Artemis is a key endonuclease in V(D)J recombination and nonhomologous end joining (NHEJ) of DNA double-strand break (DSB) repair. …”

Image_1_Efficacy of an environmental enrichment intervention for endometriosis: a pilot study.pdf by Grace De Hoyos (17124586)

“…Introduction<p>We have previously shown that Environmental Enrichment (EE), a multi-modal psychosocial intervention consisting of increased social interaction, novelty, and open spaces, improved disease presentation, anxiety, and immune-related disturbances in the rat model of endometriosis. …”

Figures for "Sonic Hedgehog Acts as a Macrophage Chemoattractant During Regeneration of the Gastric Epithelium" by Jayati Chakrabarti (9670175)

“…The recruitment of macrophages plays a central role in the regenerative process. The mechanism that regulates macrophage recruitment in response to gastric injury is largely unknown. …”

HBV Infection in Relation to Consistent Condom Use: A Population-Based Study in Peru by Antonio Bernabe-Ortiz (90790)

“…Consistent condom use was associated with decreased risk of anti-HBc. Findings from this study emphasize the need of primary prevention programs (vaccination) especially in the jungle population, and imply that condom use promotion might be a potential strategy to prevent HBV infection.…”

Granulocyte Colony-Stimulating Factor Reduces Fibrosis in a Mouse Model of Chronic Pancreatitis by Wey-Ran Lin (615284)

“…<div><p>Background</p><p>Chronic pancreatitis (CP) is a necroinflammatory process resulting in extensive pancreatic fibrosis. …”