The Impact of Prophylactic Dexamethasone on Nausea and Vomiting after Thyroidectomy: A Systematic Review and Meta-Analysis by Zhenhong Zou (645858)

“…The meta-analysis demonstrated a significant decrease in the incidence of PONV (RR 0.52, 95% CI 0.43 to 0.63, <i>P</i><0.00001), the need for rescue anti-emetics (RR 0.42, 95% CI 0.30 to 0.57, <i>P</i><0.00001), post-operative pain scores (WMD –1.17, 95% CI –1.91 to –0.44, <i>P</i> = 0.002), and the need for rescue analgesics (RR 0.65, 95% CI 0.50–0.83, <i>P</i> = 0.0008) in patients receiving dexamethasone compared to placebo, with or without concomitant antiemetics. …”

Ras Effector Mutant Expression Suggest a Negative Regulator Inhibits Lung Tumor Formation by Guillaume Vandal (469742)

“…Surprisingly there was a significant decrease in tumor number and penetrance with each KRAS effector domain mutant relative to controls, suggesting that KRAS directly activates effectors with tumor suppressive functions.…”

<i>In Vivo</i> MRI Assessment of Hepatic and Splenic Disease in a Murine Model of Schistosmiasis by Brice Masi (798438)

“…The area fraction of increased T₂ correlated (r_S = 0.83) with the area fraction of Sirius Red stained collagen in histological sections. A continuous liver T₂* decrease was also measured while brown pigments in macrophages were detected at histology. …”

Citrulline a More Suitable Substrate than Arginine to Restore NO Production and the Microcirculation during Endotoxemia by Karolina A. P. Wijnands (162718)

“…Jejunal tissues in the L-Citrulline-supplemented group showed, compared to the endotoxemic and L-Arginine-supplemented endotoxemic group, an increase in degree of phosphorylation of eNOS (Ser 1177) and a decrease in iNOS protein level. In conclusion, L-Citrulline supplementation during endotoxemia and not L-Arginine reduced intestinal microcirculatory dysfunction and increased intracellular NO production, likely via increased intracellular citrulline and arginine availability.…”

Immunocontraceptive target repertoire defined by systematic identification of sperm membrane alloantigens in a single species by Nathaly Cormier (4775262)

“…Consequently, sperm membrane alloantigens are potential targets for contraceptives that act by blocking the proteins’ functions in gamete interactions. Here we used a targeted proteomics approach to identify the major alloantigens in swine sperm membranes and lipid rafts, and thereby systematically defined the repertoire of these sperm-specific proteins in a single species. …”

Table 6_Assessment of ovarian dysfunction induced by environmental toxins: a systematic review.xlsx by Lu An (3432230)

“…Long-term exposure to particulate matter (PM)2.5 and PM10 is associated with a substantial decrease in ovarian reserve, while heavy metals (e.g., lead and cadmium) also demonstrate reproductive toxicity. …”

Table 1_Assessment of ovarian dysfunction induced by environmental toxins: a systematic review.docx by Lu An (3432230)

“…Long-term exposure to particulate matter (PM)2.5 and PM10 is associated with a substantial decrease in ovarian reserve, while heavy metals (e.g., lead and cadmium) also demonstrate reproductive toxicity. …”

Effects of anaesthesia on a model for acoustic context effects on cortical neuron responses to natural sounds. by Luciana López-Jury (8601540)

“…(<b>A</b>) The decrease of the cortical input firing rate was implemented by systematically decreasing the average input rate parameter, ν, by a factor of 1.0 (awake model) to 0.5 in steps of 0.05. …”

Tutl functions as a downstream effector of Cut-mediated regulation of da neuron dendrite development. by Mikolaj J. Sulkowski (177479)

“…(<b>H</b>) Quantitative analyses reveal a modest, yet statistically significant, decrease in overall dendritic length in animals carrying one copy of the <i>tutl^ex383</i> mutant allele relative to Cut ectopic overexpression alone. …”

Image1_The fruit fly Drosophila melanogaster as a screening model for antiseizure medications.JPEG by Florian P. Fischer (14457072)

“…</p>Results<p>In case of eas^2F mutants, treatment with the sodium channel blockers phenytoin and lamotrigine resulted in a robust reduction of seizure probability, whereas flies treated with lacosamide showed a decrease in seizure duration. …”

Table 2_Assessment of ovarian dysfunction induced by environmental toxins: a systematic review.xlsx by Lu An (3432230)

“…Long-term exposure to particulate matter (PM)2.5 and PM10 is associated with a substantial decrease in ovarian reserve, while heavy metals (e.g., lead and cadmium) also demonstrate reproductive toxicity. …”

Schematic draw of a proposed pathway for morphine- and CGP-induced regulation of midbrain and autonomic ganglions. by Igor Santana Melo (8556096)

“…Opioid receptors are expressed in PAG [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0229761#pone.0229761.ref051" target="_blank">51</a>], hypothalamus [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0229761#pone.0229761.ref052" target="_blank">52</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0229761#pone.0229761.ref053" target="_blank">53</a>], submandibular ganglia [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0229761#pone.0229761.ref018" target="_blank">18</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0229761#pone.0229761.ref046" target="_blank">46</a>] and superior cervical [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0229761#pone.0229761.ref041" target="_blank">41</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0229761#pone.0229761.ref042" target="_blank">42</a>] ganglia. …”

Cloning and Functional Analysis of FLJ20420: A Novel Transcription Factor for the BAG-1 Promoter by Hongyu Liu (103192)

“…The increased expression of FLJ20420 corresponded to a significant decrease in BAG-1 protein expression in the primary lung cancers, relative to the paired normal lung tissue controls (p = 0.0001). …”

Table_1_Industrial fishing and its impacts on food security: a systematic review.XLSX by Samantha D. Farquhar (19431634)

“…Overall, four principal themes related to the perceived positive and negative and direct and indirect impacts of industrial fishing on food security were identified: (1) Industrial fishing activities provide jobs to local populations of which earnings are used to purchase other food items; (2) Industrial fishing activities provide fisheries products to local markets which are used as a common food source; (3) Industrial fishing activities damage the environment, leading to a decrease in the availability of catch for food or livelihood; (4) Industrial fishing activities outcompete local users and export catch to distant markets, thereby decreasing available food to local communities. …”

Data and code from: Ecosystem functional response across precipitation extremes in a sagebrush steppe by Andrew Tredennick (99797)

“…</div><div>Goal is to quantify the impact of a 50% increase/decrease of precipitation on:</div><div><br></div><div>* ANPP through time</div><div>* Relationship of ANPP to soil moisture</div><div>* Species composition</div><div><br></div><div><b>Running the code</b><br></div><div><br></div><div>To fully run this code you will need R and a number of R packages.…”

Childhood blood eosinophils and symptoms of allergic disorders: a cross-sectional study in Southern China by Xiangqing Hou (12415879)

“…</p> <p>The association of eosinophils with allergic asthma/rhinitis was positively nonlinear, with a plateau at levels of Q₄ (≥0.51, 10⁹/L). …”

Frequency difference (FD) plot of G tracts in the intron downstream of internal cassette exons. A. by Erming Wang (110480)

“…FD is defined as the difference between the observed frequency of GGG in introns, calculated in a 30-nt window, and the mean frequency of GGG in 10 random permutations of the sequence in the same window, with an offset of 3nt between successive windows, as described <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0051266#pone.0051266-Yeo3" target="_blank">[10]</a>. …”

Effect of ACE inhibitors on the binding of a set of anti-ACE mAbs to blood ACE. by Maxim N. Petrov (118931)

“…<p>The binding of a set of 17 mAbs to the N and C domains of human sACE to the human serum ACE was determined using plate precipitation assay <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049290#pone.0049290-Danilov4" target="_blank">[32]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049290#pone.0049290-Danilov9" target="_blank">[49]</a> with ZPHL as a substrate. …”

In-Car Nocturnal Blue Light Exposure Improves Motorway Driving: A Randomized Controlled Trial by Jacques Taillard (125714)

“…<div><p>Prolonged wakefulness greatly decreases nocturnal driving performance. The development of in-car countermeasures is a future challenge to prevent sleep-related accidents. …”

miR-18a reduces cell HRR frequency and enhances cell radiation sensitivity. by Libing Song (203669)

“…<p><b>A,</b> DSB-induced HRR assay indicated that the overexpression of miR-18a decreased the spontaneous HR frequency in HT1080-1885 cells. …”