Assessment of Peripheral Airway Function following Chronic Allergen Challenge in a Sheep Model of Asthma by Joanne Van der Velden (192424)

“…Furthermore, while there was a decline in peripheral airway function with HDM exposure, this decrease was not correlated with the length of allergen challenge.…”

Distribution of the Mixture Model Posterior Probability of Infection Among Participants with a Rise in IgG. by Jo Walker (22404069)

“…Participants who experienced a decrease in IgG between visits were assumed to have not been infected and are not included in this figure. …”

Effect of a rosmarinic acid supplemented hemodialysis fluid on inflammation of human vascular endothelial cells by W-J. Wang (6513719)

“…Inhibition of proinflammatory mediator production in HUVECs by RA supplementation to HDF was significant in a dose-dependent manner. Exposure to RA-supplemented HDF resulted in a decrease in nitric oxide synthase expression and reduction of NO production in LPS-stimulated HUVECs. …”

Relative effort (+ standard deviation), estimated, when optimising for A) profit and B) ecological stability. by Johanna Jacomina Heymans (219773)

“…When optimising for ecological stability (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0020239#pone-0020239-g003" target="_blank">Figure 3B</a>) the relative effort will have to decrease significantly from that of 2003, and that effort with subsidies will be marginally higher than without.…”

A Mutation in the Mouse <i>Ttc26</i> Gene Leads to Impaired Hedgehog Signaling by Ruth E. Swiderski (650087)

“…Although IFT is required for ciliogenesis, the Ttc26 defect did not result in a decrease in the number or length of primary cilia. …”

Video_1_Functional Mobility Training With a Powered Knee and Ankle Prosthesis.MP4 by Suzanne B. Finucane (12394894)

“…<p>Limb loss at the transfemoral or knee disarticulation level results in a significant decrease in mobility. Powered lower limb prostheses have the potential to provide increased functional mobility and return individuals to activities of daily living that are limited due to their amputation. …”

Video_1_Functional Mobility Training With a Powered Knee and Ankle Prosthesis.MP4 by Suzanne B. Finucane (12394894)

“…<p>Limb loss at the transfemoral or knee disarticulation level results in a significant decrease in mobility. Powered lower limb prostheses have the potential to provide increased functional mobility and return individuals to activities of daily living that are limited due to their amputation. …”

Numerical investigation on the impact of natural convection on a multi-inlet industrial rooftop photovoltaic system by Xiaomeng Wang (348745)

“…Especially on the roofs of large industrial plants, it is necessary to install as many photovoltaic panels as possible while avoiding a significant increase in panel temperature that could lead to a decrease in efficiency. …”

Genetic variants in mitochondrial sirtuins associated with brain tumor risk: a case–control study by Maria Fazal Ul Haq (14659737)

“…Haplotype analysis and linkage disequilibrium (LD) showed a strong LD in brain tumor patients. Kaplan–Meier analysis showed that mutant allele frequency was found to be associated with a significant decrease in the survival of brain tumor patients.…”

eNOS-Dependent Antisenscence Effect of a Calcium Channel Blocker in Human Endothelial Cells by Toshio Hayashi (521209)

“…Exposure of HUVECs to high glucose (22 mM) for 3 days increased senescence-associated- β-galactosidase (SA-β-gal) activity, a senescence marker, and decreased telomerase activity, a replicative senescence marker. …”

<i>FOXO1</i> is a direct target of miR-582-5p. by Yanhua Liu (164798)

“…(C) Co-transfection of miR-582-5p mimics/mimics NC and <i>FOXO1</i> 3′UTR-luciferase reporter vector into HEK-293T cells demonstrated that significant decrease in luciferase activity was only found in reporter vector that contained a wild type sequence (FOXO1-3′UTR-wt), not in vector that contained a mutant sequence (FOXO1-3′UTR-mut) within the miR-582-5p binding site. …”

p53 acts as a gatekeeper by preventing progression of oncogenically activated cells to full malignancy. by George Hinkal (371132)

“…When p53 is deleted by tamoxifen injection at 3, 6, or 12 months or following IR treatment in CreERT2-p53^F/F mice, some oncogenic clones will progress to form a malignant cancer. For the p53^F/F mice, the median and maximal tumor latencies following p53 deletion decrease with age or with carcinogenic insult. …”

Supplementary Material for: Effects of exercise during chemo- or radiotherapy on immune markers – a systematic review by DeHoop A.M.S. (17085538)

“…The majority of markers was unaltered, but observed effects included a suppressive effect of exercise during radiotherapy on some pro-inflammatory markers, a preserving effect of exercise during chemotherapy on NK cell degranulation and cytotoxicity, a protective effect on the decrease in thrombocytes during chemotherapy, and a positive effect of exercise during chemotherapy on IgA. …”

The Potential Connectivity of Waterhole Networks and the Effectiveness of a Protected Area under Various Drought Scenarios by Georgina O’Farrill (564895)

“…The Greater Calakmul Region of the Yucatan Peninsula (Mexico) has experienced a 16% decrease in precipitation over the last 50 years, which we hypothesise has affected water resource connectivity. …”

Endothelial Dysfunction and Inflammation Precedes Elevations in Blood Pressure Induced by a High-Fat Diet by Jorge Camargo Oishi (5675510)

“…Results: Levels of pro-inflammatory cytokines began to increase after six weeks of a high-fat diet, while those of the anti-inflammatory cytokine adiponectin decreased. …”

Mouse Transplant Models for Evaluating the Oncogenic Risk of a Self-Inactivating XSCID Lentiviral Vector by Sheng Zhou (66217)

“…<div><p></p><p>Hematopoietic stem cell gene therapy requires the use of integrating retroviral vectors in order to stably transmit a therapeutic gene to mature blood cells. Human clinical trials have shown that some vector integration events lead to disrupted regulation of proto-oncogenes resulting in disordered hematopoiesis including T-cell leukemia. …”

Supplementary Material for: Effects of exercise during chemo- or radiotherapy on immune markers – a systematic review by DeHoop A.M.S. (17085538)

“…The majority of markers was unaltered, but observed effects included a suppressive effect of exercise during radiotherapy on some pro-inflammatory markers, a preserving effect of exercise during chemotherapy on NK cell degranulation and cytotoxicity, a protective effect on the decrease in thrombocytes during chemotherapy, and a positive effect of exercise during chemotherapy on IgA. …”

Predicting the Impact of Vaccination on the Transmission Dynamics of Typhoid in South Asia: A Mathematical Modeling Study by Virginia E. Pitzer (143006)

“…Vaccination was predicted to confer substantial indirect protection leading to a decrease in the incidence of typhoid in the short term, but (intuitively) typhoid incidence was predicted to rebound 5–15 years following a one-time campaign.…”

Effect of valve lesion on venous valve cycle: A modified immersed finite element modeling by Xiang Liu (119470)

“…The stiffening of the fibrotic leaflet led to a decrease in the orifice area and a stronger jet. …”

DataSheet2_A Zebrafish Model of Neurotoxicity by Binge-Like Methamphetamine Exposure.xlsx by Juliette Bedrossiantz (11736794)

“…After an initial testing at 20 and 40 mg/L for 48 h, the later METH concentration was selected for developing the model and the effects on the brain monoaminergic profile, locomotor, anxiety-like and social behaviors as well as on the expression of key genes of the catecholaminergic system were determined. A concentration- and time-dependent decrease in the brain levels of dopamine (DA), norepinephrine (NE) and serotonin (5-HT) was found in METH-exposed fish. …”