Image_2_Prenatal Exposure to a Maternal High Fat Diet Increases Hepatic Cholesterol Accumulation in Intrauterine Growth Restricted Rats in Part Through MicroRNA-122 Inhibition of C... by Erin K. Zinkhan (5306672)

“…In vivo inhibition of miR-122 increased hepatic Cyp7a1 protein and decreased hepatic cholesterol. Our findings suggest that IUGR combined with a maternal HFD decreased cholesterol catabolism to bile acids, in part, via miR-122 inhibition of Cyp7a1.…”

Validation of expression of HIF-lα and CypA in PDAC tissues and analysis of the clinical significance. by Huan Zhang (220065)

“…Patients with negative CypA had two- and three-year survival rates of 32.3% and 20%, respectively, which significantly decreased to 12.9% and 4.3% in patients with positive CypA (P<0.001). …”

Fibroblast growth factor 23 is upregulated in the kidney in a chronic kidney disease rat model by Hidekazu Sugiura (4922620)

“…However, the 1,25(OH)₂D₃ level was increased in the HP Nx rats and decreased in the PN rats. In all three animal models, the mRNA expression of <i>αKlotho</i>, <i>NaPi-IIa</i> and <i>NaPi-IIc</i> was decreased, and the mRNA expression of <i>TGFβ1</i>, <i>collagen1a1</i>, <i>osteopontin</i> and <i>FGF23</i> was elevated in the kidney. …”

E1784K accelerates a component of slow inactivation with 1-10s time constants. by Colin H. Peters (4430245)

“…<p><b>(A1 and A2)</b> Sample inward sodium currents recorded after 20ms to 60s repolarization pulses to -90mV following either a 500ms or 64s depolarization to -30mV. …”

Function, design, and expected use of <i>Gemini</i>, a bifunctional reporter of gene expression. by Lance Martin (257830)

“…<b>C</b>) For characterization of its enzymatic and fluorescence activities across a range of input PoPS, we placed <i>Gemini</i> under the control of a medium strength RBS (BBa_B0032) and four different promoters of variable strength (in order of decreasing strength BBa_J23119, 101, 106, 115) on a low-copy vector (BBa_PSB4A5).…”

Dynamics, diversity and experimental precision in final irrigated rice testing: a time meta-analysis by Weverton Gomes da Costa (10484908)

Simulating non-small cell lung cancer with a multiscale agent-based model-2 by Zhihui Wang (88248)

“…Note that the number of proliferations is decreasing gradually and finally disappears at a phase transition between the EGF concentrations of 2.65 × 31.1 and 2.65 × 31.2 nM. …”

Consensus time <i>τ</i> as a function of system size <i>L</i>. by Pratik Mullick (12851011)

“…<i>τ</i> decreases for lower values of <i>q</i>, however it does not exhibit a systematic dependence as <i>q</i> is made larger.…”

Improved durability of Bisphenol A polycarbonate by bilayer ceramic nano-coatings alumina-zinc oxide by Abdellah Moustaghfir (10396260)

“…However, one of the limitations in the use of ZnO is the photocatalytic oxidation that could occur at interface ZnO/PC as a consequence of the photocatalytic activity of this oxide. …”

Macroscale mechanical properties as a function of DTAF concentration and applied grip-to-grip strain level. by Spencer E. Szczesny (575976)

“…<p>(A) Samples stained at high concentrations (>10 µg/ml) maintain large positive quasi-static moduli at greater applied grip-to-grip strains, suggesting that DTAF increases the tissue yield strain. …”

Germinating but Not Resting <i>A. fumigatus</i> Conidia Display β-Glucans on the Cell Surface by Tobias M Hohl (27556)

“…<div><p>(A) The mAb 744 detects β-glucans. Decreasing laminarin concentrations were coated onto ELISA plates in the presence or absence of laminarinase. 10 μg/ml mAb 744 was added to the wells and detected using an alkaline phosphatase conjugated anti-mouse IgM.…”

The competence-supportive and competence-thwarting role of athlete leaders: An experimental test in a soccer context by Katrien Fransen (80730)

Image 2_A case report of X-linked hypophosphatemia combined with primary hyperparathyroidism.jpeg by YinQiong Wu (21803309)

“…<p>Both hypophosphatemic osteomalacia and primary hyperparathyroidism (PHPT) can lead to hypophosphatemia, but their simultaneous occurrence in the same patient is exceedingly rare. This article reports a case of a 43-year-old female patient whose primary clinical manifestations included pain in the lumbosacral and scapular regions, restricted mobility, and biochemical findings of decreased serum phosphate levels with normal parathyroid hormone (PTH) levels. …”

Image 3_A case report of X-linked hypophosphatemia combined with primary hyperparathyroidism.jpeg by YinQiong Wu (21803309)

“…<p>Both hypophosphatemic osteomalacia and primary hyperparathyroidism (PHPT) can lead to hypophosphatemia, but their simultaneous occurrence in the same patient is exceedingly rare. This article reports a case of a 43-year-old female patient whose primary clinical manifestations included pain in the lumbosacral and scapular regions, restricted mobility, and biochemical findings of decreased serum phosphate levels with normal parathyroid hormone (PTH) levels. …”

Englerin A sensitivity does not correlate with any known mutations in kidney cancer cell lines. by Florian J. Sulzmaier (126653)

“…<p>Renal cell carcinoma cell lines from the NCI-60 cell panel and a glioblastoma cell line (SF-295) were arranged by decreasing sensitivity to the englerin A natural product as determined by Akee and colleagues. …”

Table 1_A case report of X-linked hypophosphatemia combined with primary hyperparathyroidism.docx by YinQiong Wu (21803309)

“…<p>Both hypophosphatemic osteomalacia and primary hyperparathyroidism (PHPT) can lead to hypophosphatemia, but their simultaneous occurrence in the same patient is exceedingly rare. This article reports a case of a 43-year-old female patient whose primary clinical manifestations included pain in the lumbosacral and scapular regions, restricted mobility, and biochemical findings of decreased serum phosphate levels with normal parathyroid hormone (PTH) levels. …”

Image 1_A case report of X-linked hypophosphatemia combined with primary hyperparathyroidism.jpeg by YinQiong Wu (21803309)

“…<p>Both hypophosphatemic osteomalacia and primary hyperparathyroidism (PHPT) can lead to hypophosphatemia, but their simultaneous occurrence in the same patient is exceedingly rare. This article reports a case of a 43-year-old female patient whose primary clinical manifestations included pain in the lumbosacral and scapular regions, restricted mobility, and biochemical findings of decreased serum phosphate levels with normal parathyroid hormone (PTH) levels. …”

A portion of Multiple Alignment showing conservation and RE_M for each column. by Khyati Kapoor (247521)

“…The alignment is coloured in a gradient from red to yellow on the basis of decreasing conservation score. …”

Numerical calculations of the analytical model for a finite protein of N = 14 undergoing thermal denaturation. by Diego U. Ferreiro (46351)

“…<p>(A) Fraction folded as a function of temperature (<i>T</i>) at increasing ε<i>^S</i> (ε<i>ⁱ</i> = 0.5, α = 2, <i>s₀</i> = 8 fixed)(black solid lines), increasing ε<i>ⁱ</i> (ε<i>^S</i> = 2.5, <i>s₀</i> = 8 fixed) (gray lines) and decreasing <i>s₀</i> (ε<i>^S</i> = 2.5, ε<i>ⁱ</i> = 0.5 fixed) (black dashed lines). …”

Effects of thermal radiation on near-limit flame spread in a low convective microgravity environment by Praveen Kumar B (11189632)

“…If there is more radiative heat loss from the flame, the limiting oxygen concentration increases, and the size of the flamelet decreases. It was observed that in the absence of gas radiation, oscillating near-limit flamelets stabilise and merge into a single flame. …”