<i>In vitro</i> and <i>in vivo</i> Bioactivity of Stomoxyn. by Erick O. Awuoche (4603582)

“…</b> Gene-silencing validation: The relative expression of <i>stomoxyn</i> was measured from dsGFP and dsStomoxyn<i>-</i>treated <i>Gff</i> flies, showing a significant decrease in expression (<i>p</i><0.0001) in the case of dsStomoxyn<i>-</i>treated group. …”

Raw experimental data Fig 3. by Feline F. W. Benavides (13694053)

“…Additionally, we detected increased microglial activation in the olfactory bulb and hippocampus, and a decrease in the astrocytic activation status in the white matter and hippocampus of SARS-CoV-2 inoculated ferrets. …”

Data Sheet 1_Clinical isolates of Providencia rettgeri and Providencia Stuartii evades neutrophil-mediated killing by subverting neutrophil-extracellular traps.pdf by Joselyn E. Castro (22355326)

“…This decrease was abolished by fixed bacteria, and was dependent on the release of a DNase activity. …”

Table2_Location and Species Matters: Variable Influence of the Environment on the Gene Flow of Imperiled, Native and Invasive Cottontails.docx by Thomas J. McGreevy (11497954)

“…New England cottontail (Sylvilagus transitionalis) is the only native cottontail in the Northeast US, an early successional habitat specialist, and a species of conservation concern. Eastern cottontail (S. floridanus) is an invasive species in the Northeast US and a habitat generalist. …”

Data_Sheet_1_Impact of Climate Change on Hydrochemical Processes at Two High-Elevation Forested Watersheds in the Southern Appalachians, United States.pdf by Hailong Huang (1449589)

“…We find that gross primary productivity (GPP), net primary productivity (NPP), transpiration, nitrogen mineralization, and streamflow are projected to increase, while soil base saturation, and base cation concentration and ANC of streamwater are projected to decrease at the annual scale but with strong seasonal variability under a changing climate, showing the general trend of acidification of soil and streamwater despite an increase in primary productivity. …”

DataSheet_1_Human monocyte-derived suppressive cells (HuMoSC) for cell therapy in giant cell arteritis.docx by Maxime Samson (4439077)

“…</p>Results<p>Transcripts of genes implicated in vascular inflammation (CCL2, CCR2, CXCR3, HLADR), vascular remodeling (PDGF, PDGFR), angiogenesis (VEGF) and extracellular matrix composition (COL1A1, COL3A1 and FN1) were decreased in arteries treated with HuMoSCs or their supernatant. …”

<em>Lactobacillus rhamnosus</em> (<em>LGG</em>) Regulates IL-10 Signaling in the Developing Murine Colon through Upregulation of the IL-10R2 Receptor Subunit by Julie Mirpuri (109883)

“…Furthermore, <em>LGG</em>-dependent increases in IL-10R2 were associated with reductions in TNF-α, MIP-2 and disease severity in a murine model of intestinal injury in the immature colon.…”

Image 1_Global, regional and national burdens of otitis media in children and adolescents from 1990 to 2021 and its predictions to 2040.tiff by Ru Chen (186859)

“…At the national level, countries with a high burden of OM are primarily concentrated in Sub-Saharan Africa and South Asia. …”

Table_3_Metabolomics analysis of splenectomy of Nile tilapia (Oreochromis niloticus) reveals the spleen involved in regulating liver lipids and amino acids metabolism.docx by Yixi Tao (11036286)

“…After splenectomy, biochemical parameters of the liver and serum showed abnormalities, including significant increases in total cholesterol (T-CHO) and serum total bile acid (TBA) levels, alongside a significant decrease in liver TBA levels, suggesting impaired metabolic function and cholesterol deposition in the liver. …”

Data_Sheet_2_The burden of liver cirrhosis in mortality: Results from the global burden of disease study.docx by Fei Ye (339913)

“…The ASR of mortality caused by hepatitis C virus (HCV), alcohol consumption, and non-alcoholic steatohepatitis (NASH) increased with an EAPC of 0.17 (95% CI, 0.14–0.20), 0.20 (95% CI, 0.16–0.24), 1.00 (95% CI, 0.97–1.04), respectively. A decreasing trend of ASR was found among the causes of hepatitis B virus (BV) and other causes. …”

Image_3_Pharmacological Disruption of Phosphorylated Eukaryotic Initiation Factor-2α/Activating Transcription Factor 4/Indian Hedgehog Protects Intervertebral Disc Degeneration via... by Junping Bao (10931142)

“…On the contrary, further activating p-eIF2α aggravated the NP cell degeneration, with amplification of ATF4/Ihh and a higher level of ROS and apoptosis. Additionally, applying cyclopamine (CPE) to suppress Ihh was efficient to prevent NP cell apoptosis but did not decrease the ROS level. …”

Image_4_T cell receptor β repertoires in patients with COVID-19 reveal disease severity signatures.pdf by Jing Xu (15337)

“…</p>Results<p>We observed a decrease in the diversity of TCR clonotypes in COVID-19 patients compared to healthy controls. …”

Image1_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.png by Wenchao Tang (14710556)

“…</p>Results<p>Following CTD exposure, the mouse liver showed significant pathological damage and an increase in autophagic lysosomes, while the vitality of L-O2 cells showed a significant decrease. CTD led to a significant increase in the mRNA and protein levels of DDIT4 in both liver tissue and L-O2 cells, as well as a significant increase in LC3-II, Beclin1, and Bax, whereas p-mTOR and Bcl-2 were significantly decreased. …”

Table_4_The Food Additive β-Caryophyllene Exerts Its Neuroprotective Effects Through the JAK2-STAT3-BACE1 Pathway.xlsx by Yujia Zhang (757462)

“…The cell morphology altered dramatically 72 h after transfection, becoming rounder, with a decrease in cell number. BCP exhibited the potential to dramatically increase PC-12 cell viability while protecting cell morphology. …”

Data_Sheet_2_Population response of intestinal microbiota to acute Vibrio alginolyticus infection in half-smooth tongue sole (Cynoglossus semilaevis).zip by Yaotong Hao (15467570)

“…The metagenomic results suggest that a high-dose V. alginolyticus infection can significantly alter the intestinal microbiota, decrease the microbial α-diversity, and increase the bacteria from Vibrio and Shewanella, including various potential pathogens at 24 h. …”

RNAi knockdown of pex3 reduces peroxisome numbers and impairs viability. by Joseph E. Faust (580247)

“…<p>(<b>A</b>) A schematic of the pex3 genomic region shows the area targeted by the inverted repeat. …”

Data_Sheet_1_Population response of intestinal microbiota to acute Vibrio alginolyticus infection in half-smooth tongue sole (Cynoglossus semilaevis).XLSX by Yaotong Hao (15467570)

“…The metagenomic results suggest that a high-dose V. alginolyticus infection can significantly alter the intestinal microbiota, decrease the microbial α-diversity, and increase the bacteria from Vibrio and Shewanella, including various potential pathogens at 24 h. …”

UCH L1 up-regulates β-catenin signaling. by Anjali Bheda (260420)

“…<p>A. Reduction of expression of UCH L1 correlates with decrease in β-catenin protein levels. 293 cells were transfected with control GFP siRNA or two UCH L1 siRNAs in pRS vector and maintained in medium containing puromycin. …”

DataSheet_1_Reactive oxygen species-responsive supramolecular deucravacitinib self-assembly polymer micelles alleviate psoriatic skin inflammation by reducing mitochondrial oxidati... by Leiqing Yao (18533049)

“…Car@Deu@PEPS inhibited STAT3 signaling cascade with a corresponding decrease in the levels of the differentiation and proliferative markers Keratin 17 and Cyclin D1, respectively. …”

Table 1_Screening of LAB strains and their co-culture fermentation with Bacillus subtilis of Cili fruit substrate: impact on γ-aminobutyric acid enrichment, key enzyme activities,... by Angelo Uriho (20992232)

“…Compared to B. subtilis fermented substrate (Bs), a significant decrease in pH (4.89, except BsLf), increase in TTA (19.30–29.20 mL) was observed after co-culture fermentation of Cili fruit. …”