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largest decrease » largest decreases (Expand Search), larger decrease (Expand Search), marked decrease (Expand Search)
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145701
Presentation_1_Thyroid hormone elicits intergenerational epigenetic effects on adult social behavior and fetal brain expression of autism susceptibility genes.pdf
Published 2022“…<p>Genetic mutations identified in genome-wide association studies can only explain a small percentage of the cases of complex, highly heritable human conditions, including neurological and neurodevelopmental disorders. …”
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145702
Table1_Revealing the Mechanism of Huazhi Rougan Granule in the Treatment of Nonalcoholic Fatty Liver Through Intestinal Flora Based on 16S rRNA, Metagenomic Sequencing and Network...
Published 2022“…Analysis of intestinal flora showed that HRG changed the composition of intestinal flora, which was characterized by a decrease in the Firmicutes/Bacteroidetes ratio. …”
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145703
Data_Sheet_1_Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson’s disease.docx
Published 2023“…Using PD patients’ induced-pluripotent stem cells (iPSCs), we examined TFEB activity and regulation of the ALP in dopaminergic neuronal cultures generated from iPSC lines harboring heterozygous GBA1 mutations and the CRISPR/Cas9-corrected isogenic controls. Our data showed a significant decrease in TFEB transcriptional activity and attenuated expression of many genes in the CLEAR network in GBA1 mutant neurons, but not in the isogenic gene-corrected cells. …”
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145704
High-Precision Printing Sandwich Flexible Transparent Silver Mesh for Tunable Electromagnetic Interference Shielding Visualization Windows
Published 2024“…Metal mesh-based FTCFs have emerged as a promising representative in which EMI shielding effectiveness (SE) can be enhanced by increasing the line width, reducing the line spacing, or increasing mesh thickness. …”
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145705
Data_Sheet_1_Perovskite Photodetectors Based on p-i-n Junction With Epitaxial Electron-Blocking Layers.PDF
Published 2020“…This Au-MAPbI<sub>3</sub>-MAPbBr<sub>3</sub>-MAPbBr<sub>2.5</sub>Cl<sub>0.5</sub>PSCs-C60-PCBM-Ag heterostructure can be used as excellent X-ray photodetector (XPD) due to its low dark current density of 6.97 × 10<sup>−11</sup> A cm<sup>−2</sup> at −0.5 V bias, high responsivity of 870 mA/W at −100 V bias and X-ray sensitivity as high as 59.7 μC mGy<sup>−1</sup> cm<sup>−2</sup> at −50 V bias.…”
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145706
Heat map of Altered Metabolites in the VISA, JH2, Versus its Parent VSSA, JH1.
Published 2014“…Changes in abundance are indicated by color coding with red indicative of increases in mean intracellular abundance relative to the baseline (defined by the abundance in JH1) and blue indicative of decreases in intracellular abundance on a log (2) scale. …”
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145707
Reduced VEGF lowers surfactant production.
Published 2016“…(D) Mutant mice produce significantly less pro-SPC, a downstream target of VEGF-R activation. (E) Decreased levels of pro-SPB seen in mutant mice were not significant. …”
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145708
Spleen weight in mice is significantly increased by chronic CCl<sub>4</sub> treatment.
Published 2014“…<p>A. Total body weight. Total body weight of mice is significantly decreased by a 12 week-CCl<sub>4</sub> treatment. …”
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145709
Comparison of the effect of nitrate and phosphate deprivation on fatty acids, glycerides and organic acids.
Published 2018“…<p>Hierarchical cluster analysis based on mean ratio values, log2 transformed (deprived vs. replete condition at 48 and 72 h; n = 4) from the current P deprivation experiment and a previously published N deprivation experiment [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0193335#pone.0193335.ref025" target="_blank">25</a>]. …”
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145710
Shizukaol D inhibited the growth of liver cancer cells.
Published 2016“…Cell proliferation was measured by CCK-8 assay. (A) The viability of Focusand SMMC-7721cells were decreased when the cells were treated with increasing concentration of shizukaol D for 48h.…”
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145711
Time-course of BIO effects on GSK-3β activity, Akt, AMPK and MAPK signaling in contracting myotubes.
Published 2013“…(<b>D</b>) BIO decreased Erk1/2 phosphorylation with a similar time-course in myotubes cultured either in G5 or G25. …”
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145712
Supervised analyses of SFTs based on the location and mitotic count.
Published 2013“…Samples are ordered from left to right according to the decreasing correlation coefficient of their expression profile with the mean profile of the meningeal samples. …”
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145713
Characterization of Heterogeneity and Dynamics of Lysis of Single Bacillus subtilis Cells upon Prophage Induction During Spore Germination, Outgrowth, and Vegetative Growth Using R...
Published 2020“…Major findings of this work are as follows: (i) After addition of xylose to trigger prophage induction, the intensities of Raman spectral bands associated with nucleic acids of single cells in induced cultures gradually fell to zero, in contrast to the much smaller changes in protein band intensities and no changes in nucleic acid bands in uninduced cultures; (ii) the nucleic acid band intensities from an individual induced cell exhibited a rapid decrease, following a long lag period; (iii) after the addition of nutrient-rich medium with xylose, single spores underwent a long period (228 ± 41.4 min) for germination, outgrowth, and vegetative growth, followed by a short period of cell burst in 1.5 ± 0.8 min at a cell length of 8.2 ± 5.5 μm; (iv) the latent time (<i>T</i><sub>latent</sub>) between the addition of xylose and the start of cell burst was heterogeneous in cell populations; however, the period (Δ<i>T</i><sub>burst</sub>) from the latent time to the completion of cell lysis was quite small; (v) in a poor medium with l-alanine alone, addition of xylose caused prophage induction following spore germination but with longer <i>T</i><sub>latent</sub> and Δ<i>T</i><sub>burst</sub> times and without cell elongation; (vi) spontaneous prophage induction and lysis of individual cells from spores in a minimal nutrient medium were observed without xylose addition, and cell length prior to cell lysis was ∼4.1 μm, but spontaneous prophage induction was not observed in a rich medium; (vii) in a rich medium, addition of xylose at a time well after spore germination and outgrowth significantly shortened the average <i>T</i><sub>latent</sub> time. …”
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145714
File S1 - Post-Transcriptional Regulator Hfq Binds Catalase HPII: Crystal Structure of the Complex
Published 2013“…Decomposition of hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) over time shows the decrease in absorbance at λ = 240 nm. Time = 0 indicates a point just after H<sub>2</sub>O<sub>2</sub> was added. …”
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145715
Characterization of Heterogeneity and Dynamics of Lysis of Single Bacillus subtilis Cells upon Prophage Induction During Spore Germination, Outgrowth, and Vegetative Growth Using R...
Published 2020“…Major findings of this work are as follows: (i) After addition of xylose to trigger prophage induction, the intensities of Raman spectral bands associated with nucleic acids of single cells in induced cultures gradually fell to zero, in contrast to the much smaller changes in protein band intensities and no changes in nucleic acid bands in uninduced cultures; (ii) the nucleic acid band intensities from an individual induced cell exhibited a rapid decrease, following a long lag period; (iii) after the addition of nutrient-rich medium with xylose, single spores underwent a long period (228 ± 41.4 min) for germination, outgrowth, and vegetative growth, followed by a short period of cell burst in 1.5 ± 0.8 min at a cell length of 8.2 ± 5.5 μm; (iv) the latent time (<i>T</i><sub>latent</sub>) between the addition of xylose and the start of cell burst was heterogeneous in cell populations; however, the period (Δ<i>T</i><sub>burst</sub>) from the latent time to the completion of cell lysis was quite small; (v) in a poor medium with l-alanine alone, addition of xylose caused prophage induction following spore germination but with longer <i>T</i><sub>latent</sub> and Δ<i>T</i><sub>burst</sub> times and without cell elongation; (vi) spontaneous prophage induction and lysis of individual cells from spores in a minimal nutrient medium were observed without xylose addition, and cell length prior to cell lysis was ∼4.1 μm, but spontaneous prophage induction was not observed in a rich medium; (vii) in a rich medium, addition of xylose at a time well after spore germination and outgrowth significantly shortened the average <i>T</i><sub>latent</sub> time. …”
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145716
Characterization of Heterogeneity and Dynamics of Lysis of Single Bacillus subtilis Cells upon Prophage Induction During Spore Germination, Outgrowth, and Vegetative Growth Using R...
Published 2020“…Major findings of this work are as follows: (i) After addition of xylose to trigger prophage induction, the intensities of Raman spectral bands associated with nucleic acids of single cells in induced cultures gradually fell to zero, in contrast to the much smaller changes in protein band intensities and no changes in nucleic acid bands in uninduced cultures; (ii) the nucleic acid band intensities from an individual induced cell exhibited a rapid decrease, following a long lag period; (iii) after the addition of nutrient-rich medium with xylose, single spores underwent a long period (228 ± 41.4 min) for germination, outgrowth, and vegetative growth, followed by a short period of cell burst in 1.5 ± 0.8 min at a cell length of 8.2 ± 5.5 μm; (iv) the latent time (<i>T</i><sub>latent</sub>) between the addition of xylose and the start of cell burst was heterogeneous in cell populations; however, the period (Δ<i>T</i><sub>burst</sub>) from the latent time to the completion of cell lysis was quite small; (v) in a poor medium with l-alanine alone, addition of xylose caused prophage induction following spore germination but with longer <i>T</i><sub>latent</sub> and Δ<i>T</i><sub>burst</sub> times and without cell elongation; (vi) spontaneous prophage induction and lysis of individual cells from spores in a minimal nutrient medium were observed without xylose addition, and cell length prior to cell lysis was ∼4.1 μm, but spontaneous prophage induction was not observed in a rich medium; (vii) in a rich medium, addition of xylose at a time well after spore germination and outgrowth significantly shortened the average <i>T</i><sub>latent</sub> time. …”
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145717
Integrity of AWC cilia structure is critical for proper localization of EGL-4.
Published 2009“…Calcium levels in AWC have been shown to decrease after ligand binding <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000761#pgen.1000761-Chalasani1" target="_blank">[13]</a>. …”
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145718
Experimental tasks and model framework.
Published 2023“…The visuomotor system evaluates the accuracy of the motor command with respect to the postdicted target position (<i>E</i><sub><i>post</i></sub>) in order to adapt its gains <i>ω</i><sub><i>v</i></sub>, <i>ω</i><sub><i>m</i></sub> and <i>ω</i><sub><i>cd</i></sub>. A decrease of <i>ω</i><sub><i>m</i></sub> (inward learning) is controlled by downregulating saccade peak velocity while an increase of <i>ω</i><sub><i>m</i></sub> (outward learning) is controlled by upregulation of saccade duration. …”
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145719
RBC-NOSSer1177 levels during weight reduction protocols.
Published 2015“…<p>(A) Bars showed statistically decreased RBC-NOS<sup>Ser1177</sup> phosphorylation Post 1 RWR compared to Pre 1 and 2 RWR (<i>P</i><0.05, respectively). …”
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145720
Down regulated PDI attenuates CNP-mediated cGMP activation in HMCs.
Published 2014“…<p><b>A</b>. Western blotting with RL90 antibody shows partial knockdown of PDI in HMCs. …”