Table_3_Identification of Robust Biomarkers for Early Predicting Efficacy of Subcutaneous Immunotherapy in Children With House Dust Mite-Induced Allergic Rhinitis by Multiple Cytok... by Shaobing Xie (11935328)

“…The potential cytokines were further validated by enzyme-linked immunosorbent assay (ELISA) in a cohort with 54 responders and 26 non-responders.…”

Data_Sheet_1_Tilianin Extracted From Dracocephalum moldavica L. Induces Intrinsic Apoptosis and Drives Inflammatory Microenvironment Response on Pharyngeal Squamous Carcinoma Cells... by Hailun Jiang (6575330)

“…Combined, these results showed that tilianin treatment increased cytotoxicity as well as the apoptotic population of FaDu cells in a dose-dependent manner. Furthermore, tilianin treatment decreased the level of anti-apoptotic markers Bcl-2 and Bcl-xL, increased the level of apoptotic factors Bad and Bax, and stimulated cytochrome c release, caspase-3 and poly ADP ribose polymerase (PARP) activation in FaDu cells. …”

<i>inx-18</i> and <i>inx-19</i> play distinct roles in ASK-ASH electrical synapse localization and function. by Lisa Voelker (7553510)

“…<p>A) <i>inx-</i>19 cDNA was expressed using <i>Psra-9</i> and fluorescent puncta in the nerve ring were counted in N2 (wild-type), <i>inx-18(ok2454)</i> and <i>inx-19(tm1896)</i> backgrounds. …”

Table_2_GLT-1 Knockdown Inhibits Ceftriaxone-Mediated Improvements on Cognitive Deficits, and GLT-1 and xCT Expression and Activity in APP/PS1 AD Mice.DOC by JunXia Gao (9464678)

“…This upregulation might be a compensatory change against the accumulated glutamate resulting from GLT-1 impairment. …”

Table 5_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls by Xue Li (285380)

“…Immunofluorescence and WB confirmed a reduction in the dopaminergic neuron count after co-DR1/2I.…”

Presentation_1_Impact of BAFF Blockade on Inflammation, Germinal Center Reaction and Effector B-Cells During Acute SIV Infection.pptx by Gwenoline Borhis (8518077)

“…From day 2 post-infection (dpi), Treated macaques received one weekly injection of BR3-Fc molecule, a soluble BAFF antagonist, for 4 weeks. Whereas, the kinetics of CD4⁺ T-cell loss and plasma viral loads were comparable in both groups, BAFF blockade delayed the peak of inflammatory cytokines (CXCL10, IFNα), impaired the renewal of plasmacytoid dendritic cells and fostered the decline of plasma CXCL13 titers after 14 dpi. …”

Presentation_2_Impact of BAFF Blockade on Inflammation, Germinal Center Reaction and Effector B-Cells During Acute SIV Infection.pptx by Gwenoline Borhis (8518077)

“…From day 2 post-infection (dpi), Treated macaques received one weekly injection of BR3-Fc molecule, a soluble BAFF antagonist, for 4 weeks. Whereas, the kinetics of CD4⁺ T-cell loss and plasma viral loads were comparable in both groups, BAFF blockade delayed the peak of inflammatory cytokines (CXCL10, IFNα), impaired the renewal of plasmacytoid dendritic cells and fostered the decline of plasma CXCL13 titers after 14 dpi. …”

Table_1_Derivation of Breast Cancer Cell Lines Under Physiological (5%) Oxygen Concentrations.DOCX by Euphemia Y. Leung (595077)

“…We have derived and grown a series of four human breast cancer cell lines under 5% oxygen, and have compared their properties to those of established breast cancer lines growing under ambient oxygen.…”

Da-Yuan-Yin decoction suppresses NETs formation, inhibits the IL-23/JAK2/STAT3 signalling pathway, and modulates metabolic profiles and gut microbiota composition in damp-heat synd... by Yun Yang (417125)

“…<p>Da-Yuan-Yin Decoction (DYY), used since the early Qing Dynasty in China for damp-heat syndrome, was evaluated for its comprehensive protective effects.</p> <p>Rats received a high-fat/high-sugar diet for 14 days, then daily exposure to high temperature/humidity (31.0 ± 0.5°C, 85%-95%) for 10 hours over 14 days. …”

Table 1_Cell-free supernatant of Levilactobacillus brevis (RAMULAB51) from coconut inflorescence sap (Neera) enhances glucose uptake and PPAR-γ in 3T3-L1 adipocytes and inhibits α-... by Chandana Kumari V B (17543976)

“…It strongly co-aggregated with Micrococcus luteus and Bacillus subtilis, showing significant antimicrobial activity with a 24 mm inhibition zone against Micrococcus luteus. …”

Expression of COX-2, IL-1β, and TOLLIP after treatment with lipopolysaccharide or IL-1β as an inflammatory stimulus. by Yu Hui Won (3331458)

“…<p>(A) Validation of COX-2 by induced inflammation with LPS in fibroblasts from ALS patients (lane 1, untreated ALS patient-derived iPSCs; lane 2, 1 μg/mL LPS-treated ALS patient-derived iPSCs; lane 3, 5 μg/mL LPS-treated ALS patient-derived iPSCs; lane 4, untreated normal-derived iPSCs; lane 5, 1 μg/mL LPS-treated normal-derived iPSCs; lane 6, 5 μg/mL LPS-treated normal-derived iPSCs). …”

Class I histone deacetylase inhibitor MS-275 attenuates vasoconstriction and inflammation in angiotensin II-induced hypertension by Yuhee Ryu (3370769)

“…</p><p>Methods and results</p><p>MS-275 inhibited the activity of HDAC1, HDAC2, and HDAC3, while RGFP966 weakly inhibited that of HDAC3 in a cell-free system. MS-275 and RGFP966 treatment reduced systolic blood pressure and thickness of the aorta wall in Ang II-induced hypertensive mice. …”

FIGURE 1 from Inhibition of PRL2 Upregulates PTEN and Attenuates Tumor Growth in <i>Tp53</i>-deficient Sarcoma and Lymphoma Mouse Models by Frederick Nguele Meke (17718099)

“…<p>PRL2 expression inversely correlates with PTEN and survival in human patients with sarcoma. <b>A,</b> Scatter plot of PRL2 mRNA data showing the increased expression of PRL2 mRNA in patients with TCGA SARC with TP53 mutations. …”

Datasheet1_Breathing pattern and pulmonary gas exchange in elderly patients with and without left ventricular dysfunction—modification with exercise-based cardiac rehabilitation an... by Prisca Eser (3873718)

“…</p>Methods<p>In this large multicentre observational longitudinal study, patients aged ≥65 years with acute or chronic coronary syndromes (ACS, CCS) without cardiac surgery who participated in a study on the effectiveness of exCR in seven European countries were included. …”

Yeast essential gene screens for modulators of αSyn toxicity. by Blagovesta Popova (14546)

“…<p><b>(A)</b> Growth assays of yeast cells expressing <i>GAL1</i>-driven αSyn-GFP from two genomically integrated copies in Y7092 background, used as query strain in the <i>Tet</i>-Promoters Hughes collection (yTHC) and decreased abundance by mRNA perturbation (DAmP) collection screens, with empty vector as control. …”

Image_1_Roles of Cadherin2 in Thyroid Cancer.tif by Yun Chen (279569)

“…Background<p>The majority of drug-resistant cells in Thyroid cancer (THCA) tend to exhibit an Epithelial mesenchymal transition (EMT) phenotype, and abnormal expression of the cell adhesion molecule Cadherin2 (CDH2) is a hallmark of EMT. However, the roles of CDH2 in THCA and its underlying mechanisms are unknown.…”

Semi-knockout YAP rescue heart function from valve thickening. by Wei Yu (43094)

“…<p>(A) Gross front view of hearts from 9-month-old <i>Tie2</i>^<i>Cre+</i><i>;Vgll4</i>^<i>fl/-</i>; <i>Tie2</i>^<i>Cre+</i><i>;Vgll4</i>^<i>fl/-</i><i>;Yap</i>^<i>fl/+</i> and <i>Vgll4</i>^<i>fl/-</i><i>;Yap</i>^<i>fl/+</i> hearts. …”

Intraplantar acid injection produced TRPV1-mediated time-dependent behavioral hyperalgesia and spinal neuron sensitization. by He Liu (67509)

“…<p>(A) Intraplantar injection of pH 5.0 PBS (10-µl), not pH 7.4 PBS (10-µl), produced thermal (top) and mechanical (bottom) hyperalgesia. …”

Data Sheet 1_Improved myocardial mitochondrial energy metabolism in rats with chronic heart failure by modifying fatty acid oxidation using an extract of sand-fired aconite (Jianch... by Hongtao Zhang (167639)

“…This study investigated myocardial mitochondrial energy metabolism as a therapeutic mechanism of SFAS in doxorubicin-induced chronic heart failure (CHF) rats.…”

Image_3_Abnormal Shift in B Memory Cell Profile Is Associated With the Expansion of Circulating T Follicular Helper Cells via ICOS Signaling During Acute HIV-1 Infection.tif by Xiaofan Lu (2319541)

“…Twenty-five study subjects were enrolled from the Beijing PRIMO clinical cohort, a prospective cohort of HIV-1-negative men who have sex with men (MSM) for the identification of cases of acute HIV-1 infection (AHI) at Beijing Youan Hospital, Capital Medical University. …”