A comparison of diversity and composition between ileal and cecal microbiotas. by Zhui Li (4237462)

Schematic of nab paclitaxel preparation via a novel method. by Yue Gao (263086)

The <i>Tnni2^K175del</i> mutation disturbed bone development of mice. by Xiaoquan Zhu (589276)

“…<p>Skeletons staining using Alcian blue for cartilage (blue) and Alizarin Red S for calcified bone (red). (A) Decreased mineralization (<i>arrows</i>) in the calvarias from <i>Tnni2^{K175del/K175del}</i> mice at E16.5 and from <i>Tnni2^+K175del</i> mice at P2 and P5 compared to their wild-type littermates, respectively. …”

Metascape pathway analysis of significant upregulated or downregulated genes in adult cholestatic liver disease (aCLD) samples (n = 3) compared to adult normal (aNormal) samples (n... by Alyssa Kriegermeier (4707226)

Effect of aging on cellular senescence in the mouse kidney. by Lihua Qiu (178071)

Subjects:

Evaluation of 309 molecules as inducers of CYP3A4, CYP2B6, CYP1A2, OATP1B1, OCT1, MDR1, MRP2, MRP3 and BCRP in cryopreserved human hepatocytes in sandwich culture by Pekka Kallunki (398041)

“…MRP2 was induced by 27 compounds followed by MDR1 (16) > BCRP (9) > OCT1 (8) > OATP1B1 (5) > MRP3 (2).</p><p>3. CYP3A4 appeared to be down-regulated (≥2-fold decrease in mRNA expression) by 53 compounds, 10 for CYP2B6, 6 for OCT1, 4 for BCRP, 2 for CYP1A2 and OATP1B1 and 1 for MDR1 and MRP2.…”

House Dust Mite Allergen Regulates Constitutive Apoptosis of Normal and Asthmatic Neutrophils via Toll-Like Receptor 4 by Do Hyung Kim (739231)

“…DP delayed cleavage of procaspase 9 and procaspase 3 and the decrease in Mcl-1 expression. Supernatant collected from DP-treated normal neutrophils inhibited the constitutive apoptosis of normal neutrophils, and S100A8 and S100A9 were identified as anti-apoptotic proteins in the supernatant. …”

Thresholds and group reproducibility. by Jan Willem Koten (17743224)

Effect of sample size on reproducibility. by Jan Willem Koten (17743224)

The dominant negative effects of G304S increase over time. by Altar Sorkaç (3391754)

“…<p>(A) <i>eat-6(rt252)</i> heterozygous animals had decreased pumping rates as young adults. …”

The changes of EFR3A expression in the organ of Corti in the animals treated with kanamycin and furosemide by western blotting. by Chen Nie (686387)

“…By the 15th day the EFR3A expression decreased to nearly normal level. …”

EAT-6 G304S mutation is analogous to ATP1A3 G316S and perturbs neuromuscular junction function. by Altar Sorkaç (3391754)

“…<p>(A) EAT-6 is homologous to ATP1A3 and glycine 304 (G304) is in a well-conserved region. …”

<i>In Vivo</i> Modelling of <i>ATP1A3</i> G316S-Induced Ataxia in <i>C</i>. <i>elegans</i> Using CRISPR/Cas9-Mediated Homologous Recombination Reveals Dominant Loss of Function Def... by Altar Sorkaç (3391754)

“…<div><p>The NIH Undiagnosed Diseases Program admitted a male patient with unclassifiable late-onset ataxia-like symptoms. …”

S1 Data - by Jan Willem Koten (17743224)

“…The mean connectivity decreased to r = 0.09 (95% CI 0.03–0.16) when test-retest reliability and auto-correlations of single time courses were considered, indicating that less than a quarter of connectivity is detectable. …”

Connectivity statistics. by Jan Willem Koten (17743224)

“…The mean connectivity decreased to r = 0.09 (95% CI 0.03–0.16) when test-retest reliability and auto-correlations of single time courses were considered, indicating that less than a quarter of connectivity is detectable. …”

Hypothetical versus random connectomes. by Jan Willem Koten (17743224)

A Gain-of-Function Mutation in <i>Tnni2</i> Impeded Bone Development through Increasing <i>Hif3a</i> Expression in DA2B Mice by Xiaoquan Zhu (589276)

“…The increased amount of hif3a resulted in impairment of angiogenesis, delay in endochondral ossification, and decrease in chondrocyte differentiation and osteoblast proliferation, suggesting that hif3a counteracted hif1a-induced <i>Vegf</i> expression in DA2B mice. …”

Reproducibility of response time and brain measures. by Jan Willem Koten (17743224)

K-means clustering was performed to cluster the genes according to their expression kinetics. by Seon-Pil Jin (17364626)

More focal female offspring produced on dishes where the prior occupant was a related female, while more conspecific offspring were produced on dishes where the female was unrelate... by Emily Rakosy (20939774)