MicroRNA let-7c Inhibits Cell Proliferation and Induces Cell Cycle Arrest by Targeting CDC25A in Human Hepatocellular Carcinoma by Xiuming Zhu (729756)

“…The results showed that the expression levels of let-7c were significantly decreased in HCC cell lines. Overexpression of let-7c repressed cell growth, induced cell apoptosis, led to G1 cell cycle arrest in vitro, and suppressed tumor growth in a HepG2 xenograft model in vivo. …”

Modifying the thresholds of MT and HT fibers does not have a significant effect on CAP features for different HHL scenarios. by Maral Budak (6680351)

“…<p>(A)The rate-intensity curves for different fiber types (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008499#pcbi.1008499.g002" target="_blank">Fig 2E</a> for unmodified curves) are modified to have a more clear distinction between the activity thresholds of different fiber types, as in Fig 3 of [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008499#pcbi.1008499.ref012" target="_blank">12</a>]. …”

Dual-targeting approaches show agonistic effects in cell survival decrease due to either apoptotic cell death enhancement or cooperative PI3K-Akt-mTOR pathway downregulation. by Elke Tatjana Aristizabal Prada (833927)

Loss of FAM83A expression induces apoptosis and inhibits PI3K/Akt signaling. by Courtney A. Bartel (3993173)

“…(D) Immunoblot analysis of the apoptotic marker cleaved caspase 3 and cell signaling proteins shows FAM83A knockdown induces apoptosis while decreasing PI3K/Akt signaling.…”

Relative levels of <i>islet</i> and downstream gene transcripts in morphants vs. mutants. by Rosa L. Moreno (5434796)

“…Both morphants and Ctl MO-injected embryos had significantly decreased levels of <i>islet1</i>. The largest change detected was a ~ 4-fold increase in <i>islet2a</i> levels in morphant compared to wildtype or mutant. ***, p<0.001; **, p<0.003; *, p<0.005; ANOVA with post hoc Bonferroni. …”

Genetic interactions between <i>ncp1</i> and auxin signaling mutants. by Xiaona Cui (2550136)

“…<p>(A) From left to right: adult plants of WT, <i>ncp1</i>, <i>tir1-1</i>, <i>ncp1 tir1-1</i>, <i>tir1-1 afb2-1 afb3-1</i>, <i>ncp1 tir1-1 afb2-1 afb3-1</i>. …”

Downregulated miR-29a/b/c during Contact Inhibition Stage Promote 3T3-L1 Adipogenesis by Targeting DNMT3A by Yingjie Zhu (240610)

“…In the present study, we found that the expression level of miR-29a/b/c was decreased and the expression of DNMT3A was up-regulated during CI stage, respectively. …”

a Overlay of electropherograms and by Vanessa Radtke (1674097)

Vasostatin-1: A novel circulating biomarker for ileal and pancreatic neuroendocrine neoplasms by Andrea Corsello (5172026)

“…Treatment of patients with somatostatin analogues decreased both total-CgA and VS-1. In contrast, administration of PPIs increased the plasma levels of total-CgA, but not of VS-1.…”

TM9SF4 decreases during vitamin D3-induced Mo differentiation of U937 cells, but increases during ATRA-induced G differentiation of HL-60 cells. by Rosa Paolillo (736953)

Individual well-being measured by mean PANAS-positive affect and PANAS-negative affect scores in the study period for all women. by Francesca Bardi (4593034)

Cxcr4 promotes Cyclin D1 expression through ERK signaling during DFC proliferation. by Jingwen Liu (517390)

“…<p>(A) ERK1/2 phosphorylation levels were dramatically decreased in <i>cxcr4a</i>^<i>um20</i> mutants. …”

Homozygous deletion of the orthologous murine <i>Ikzf1</i> enhancer results in significantly decreased <i>Ikzf1</i> expression, increased cell proliferation, and altered B cell dif... by Vincent U. Gant (9955199)

Decreased CD4⁺ cell cytokine production, macrophage phagocytosis and bacterial clearance in CLP-induced Atg7^f/fCD4-Cre mice. by Chih-Wen Lin (599080)

Lexis diagram of birth year and test participation. by Anders H. Hjulmand (18476019)

Map of federal study sites. by Kira Minehart (21029571)

Map of state study sites. by Kira Minehart (21029571)

Map of local study sites. by Kira Minehart (21029571)

Map of 91 federal, state, and local parks and protected area (PPA) study sites overlaid on Level 2 ecoregion. by Kira Minehart (21029571)

Alpha-smooth muscle actin (ASMA) is decreased and vimentin is increased in dilated bicuspid aortic valve (BAV)-associated aortas. by Brittany Balint (6829967)