Image_1_Kinetics of Phenotypic and Functional Changes in Mouse Models of Sponge Implants: Rational Selection to Optimize Protocols for Specific Biomolecules Screening Purposes.TIF by Mariana Ferreira Lanna (9717680)

“…Here, the changes in histological/morphometric, immunophenotypic and functional features of infiltrating leukocytes (LEU) were assessed in sponge implants for Swiss, BALB/c, and C57BL/6 mice. A gradual increase of fibrovascular stroma and a progressive decrease in LEU infiltration, mainly composed of polymorphonuclear cells with progressive shift toward mononuclear cells at late time-points were observed over time. …”

Image_2_Metabolic reprogramming through mitochondrial biogenesis drives adenosine anti-inflammatory effects: new mechanism controlling gingival fibroblast hyper-inflammatory state.... by Nathalie Paladines (16035533)

“…Introduction<p>Fibroblasts are the dominant stromal cells in the gingival lamina propria with a well-established relevance in regulation of inflammation, and in innate immunity. …”

Image_1_Lyme borreliosis in pregnancy and associations with parent and offspring health outcomes: An international cross-sectional survey.PDF by Katherine Leavey (697697)

“…Background<p>Lyme disease (LD) is a complex tick-borne pathology caused by Borrelia burgdorferi sensu lato bacteria. …”

Image_1_Parasitemia and Associated Immune Response in Pregnant and Non-Pregnant Beef Cows Naturally Infected With Neospora caninum.TIF by Ignacio Gual (12871562)

“…This correlates with higher antibody levels and a decrease in total leukocyte counting. The precise timing of the parasitemia may be used for diagnosis purposes and/or for design strategies to avoid vertical transmission. …”

DataSheet1_Exploring the naturally acquired response to Pvs47 gametocyte antigen.docx by Gisele Tatiane Soares da Veiga (19828473)

“…Anti-Pvs47 IgM and IgG responses in symptomatic individuals decrease over time. Furthermore, we observed a negative correlation between anti-Pvs47 IgM response and gametocytemia in samples of symptomatic patients, indicating a gametocyte-specific response. …”

Dietary sodium butyrate improves intestinal development and function by modulating the microbial community in broilers by Wei Wu (27708)

“…Furthermore, we found a striking decrease in <i>Enterobacteriaceae</i> and increases in <i>Lachnospiraceae</i> and <i>Rikenellaceae</i> in the cecal lumen of birds fed 800 mg/kg SB as well as a higher proportion of <i>Ruminococcaceae</i> and a noticeable reduction (<i>P</i><0.05) of <i>Lactobacillaceae</i> in birds treated with 400 mg/kg SB. …”

Afriplex GRT(TM) extract attenuates hepatic steatosis in an 'in vitro' model of NAFLD by Kwazi Gabuza (18397795)

“…Rooibos has been previously shown to decrease inflammation and oxidative stress in experimental models of diabetes, however, this is yet to be explored in a setting of NAFLD. …”

Transfer of OVA-expressing tumor cells into wild-type mice results in loss of antigen and induction of MHC on lymphoma cells. by Armin Gerbitz (174530)

“…<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034552#s1" target="_blank">Introduction</a> of either GFP alone (291GFP) or OVA-IRES-GFP (291OVA) into lymphoma cells resulted in loss of or strong decrease in GFP expression in outgrowing lymphomas after transfer into wild-type mice (left panel, n = 6). …”

Image_4_Deleterious Effect of High-Fat Diet on Skeletal Muscle Performance Is Prevented by High-Protein Intake in Adult Rats but Not in Old Rats.JPEG by Eleonora Poggiogalle (284998)

“…In adult rats high-protein intake combined with high-fat diet determined a lower decrease in relative isometric torque, normalized to either FFM or body weight, compared with adult rats fed a high-fat normal-protein diet. …”

Image_1_Deleterious Effect of High-Fat Diet on Skeletal Muscle Performance Is Prevented by High-Protein Intake in Adult Rats but Not in Old Rats.JPEG by Eleonora Poggiogalle (284998)

“…In adult rats high-protein intake combined with high-fat diet determined a lower decrease in relative isometric torque, normalized to either FFM or body weight, compared with adult rats fed a high-fat normal-protein diet. …”

<i>Chlamydia trachomatis</i> Pgp3 Antibody Population Seroprevalence before and during an Era of Widespread Opportunistic Chlamydia Screening in England (1994-2012) by Sarah C. Woodhall (448596)

“…A decrease in age-specific cumulative incidence following national implementation of opportunistic chlamydia screening has not yet been demonstrated. …”

Table_6_Cyclic adenosine monophosphate/phosphodiesterase 4 pathway associated with immune infiltration and PD-L1 expression in lung adenocarcinoma cells.xls by Ling Tong (632992)

“…In the cell experiment, forskolin (an adenylate cyclase activator) and zardaverine (a PDE4 inhibitor) enhance the cAMP pathway and decrease PD-L1 expression, while SQ2253 (an adenylate cyclase inhibitor) inhibits the cAMP pathway and increases PD-L1 expression of the LUAD cell lines H1299 and A549, and MYC regulation by these drugs was positively correlated with PD-L1 regulation, which verified the regulation of the cAMP/PDE4 pathway on MYC and PD-L1.…”

Phosphate Diester Hydrolysis and DNA Damage Promoted by New <i>cis</i>-Aqua/Hydroxy Copper(II) Complexes Containing Tridentate Imidazole-rich Ligands by Marciela Scarpellini (2382364)

“…Complex <b>1</b> effectively promoted the hydrolytic cleavage of double-strand plasmid DNA under anaerobic and aerobic conditions, with a rate constant of 0.28 h^-1 for the decrease of form I, which represents about a 10⁷ rate increase compared with the estimated uncatalyzed rate of hydrolysis.…”

DataSheet1_Plasmodium Circumsporozoite Protein Enhances the Efficacy of Gefitinib in Lung Adenocarcinoma Cells by Inhibiting Autophagy via Proteasomal Degradation of LC3B.PDF by Xiao Lu (355468)

“…In the OE-CSP group, autophagy was significantly inhibited, and there was a decrease in LC3B protein after exposure to gefitinib. …”

Table1_Dynamic Dust Source Regions and the Associated Natural and Anthropogenic Dust Emissions at the Global Scale.DOCX by Zhen Wang (72451)

“…The AD emissions exhibit a decreasing trend in northern China, western India, the southern side of the Sahara Desert, and the central United States from 2001 to 2018 due to the implementation of environmental protection policies and a decrease in the wind speed, with the highest rate of decline reaching −74.9 μg m⁻² s⁻¹/decade. …”

Table_1_Circular RNA Expression Profiling Identifies Glaucoma-Related Circular RNAs in Various Chronic Ocular Hypertension Rat Models.XLS by Xiaoxiao Chen (1673935)

“…The expression of hsa_circ_0023826 showed a significant decrease in glaucoma patients, while TENM4 mRNA showed no significant difference compared to cataract patients (P = 0.024 and P = 0.294, respectively). …”

DataSheet_1_Cyclic adenosine monophosphate/phosphodiesterase 4 pathway associated with immune infiltration and PD-L1 expression in lung adenocarcinoma cells.zip by Ling Tong (632992)

“…In the cell experiment, forskolin (an adenylate cyclase activator) and zardaverine (a PDE4 inhibitor) enhance the cAMP pathway and decrease PD-L1 expression, while SQ2253 (an adenylate cyclase inhibitor) inhibits the cAMP pathway and increases PD-L1 expression of the LUAD cell lines H1299 and A549, and MYC regulation by these drugs was positively correlated with PD-L1 regulation, which verified the regulation of the cAMP/PDE4 pathway on MYC and PD-L1.…”

Data_Sheet_1_An automated heart rate-based algorithm for sleep stage classification: Validation using conventional polysomnography and an innovative wearable electrocardiogram devi... by Nicolò Pini (11370516)

“…AHI and biological sex did not affect scoring, while a significant decrease of performance by age was reported across the models. …”

The prevalence of depression and associated risk factors among medical students: An untold story in Vietnam by Tung Pham (6406841)

“…<div><p>Background</p><p>Depression is a common mental health problem in medical students worldwide. …”

Data_Sheet_1_An analysis of African Swine Fever consequences on rural economies and smallholder swine producers in Haiti.docx by Ralph P. Jean-Pierre (13945596)

“…The 2021 outbreaks in the Dominican Republic and Haiti pose threats to animal health, livestock markets, and producer livelihoods. A partial equilibrium Haitian pig sector model (HPM-2021) was developed to assess the economic impacts of a 2021 Haitian ASF outbreak of a similar size to the 1980s outbreak. …”