Gait, Cognition and Associated Risk Factors: Insights from SHARE and TILDA by Fiachra J Maguire (1374951)

“…The primary hypothesis for this objective is that there is a measureable decrease in cognitive function in those who demonstrated slow gait at an earlier stage in the study. …”

Surface Modifications of an Organic Polymer-Based Microwire Platform for Sustained Release of an Anti-Inflammatory Drug by Chuan Liu (367528)

“…Quantitative real-time polymerase chain reaction (qRT-PCR) was used to assess the mRNA expression of certain inflammatory-related genes. In general, a decrease in fold-change expression was observed for all genes tested for Dex-loaded wires compared with controls (functionalized but no drug). …”

Influence of <i>k</i>₁ on the homeostatic behavior of the m7 ping-pong controller when <i>E</i>₁ binds first to free enzyme <i>Ez</i>. by Qaiser Waheed (5095328)

“…(c) A decrease of <i>k</i>₆ from 5.0 to 1.0 while <i>k</i>₁ is kept at 100.0 gives a general improvement of the homeostatic performance of the ping-pong controller, except for the higher end <i>k</i>₅ range between 900–1000, where <i>A</i>_<i>ss</i> becomes constant (indicated by the red circle). …”

Histopathological analyses of hearts and aortic walls. by Victoria Campuzano (185466)

“…<p>(A) Treatments with both losartan and apocynin effectively contributed to a normal heart weight relative to body weight, in DD mice. …”

Effects of aging and exposure to high-fat diet on spatial strategy use in the Barnes maze. by James P. Kesby (811190)

“…<p>Spatial (<b>A,D,G</b>), serial (<b>B,E,H</b>) and mixed/random (<b>C,F,I</b>) strategy use by adult and aged mice on control diet (CD) and high-fat diet (HFD) on the Barnes maze acquisition days (a1-a5), retention day (Ret) and reversal learning days (Rv1-Rv2). …”

LRP1 overexpression in LRP1 hypothalamic knockdown mice rescues leptin signaling and metabolic phenotype. by Qiang Liu (166143)

“…<p>(A–D) <i>Lrp1</i> floxp mice were injected bilaterally in the hypothalamus with Cre lentivirus, Cre lentivirus plus mLRP2 lentivirus, or control GFP lentivirus. …”

Meiotic defects in GC-Dcr1 and GC-Dgcr8 mutant testes. by Céline Zimmermann (558274)

“…<p>(A–D) Anti-γH2AX (green), present in the entire nucleus in early meiotic stages and located to the XY body during the pachytene stage, indicates a decreased number of tubules containing XY body positive cells in GC-Dcr1 and GC-Dgcr8 mutant testes compared to controls at P12. …”

Effect of COMP-Ang-1 on Cx26, Cx32, Cx43 and TNFα expression in sciatic nerves. by Joanna Kosacka (330426)

“…<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0032881#s3" target="_blank">Results</a> are presented as mean ±SEM. * p≤0.05, ** p≤0.01, *** p≤0.001, according to the one-way analysis of variance together with the Newman-Keuls test (n = 4).…”

MDMA-induced axotomy of serotonergic neurons in the striatum. by Chuang-Hsin Chiu (796893)

“…Data are presented as mean and S.D. values (** <i>p</i><0.01). There was a statistically significant reduction in the OD ratio after MDMA treatment.…”

CO suppression of LPS-induced IL-1β transcription, mRNA expression, and protein production. by Maneesha Chhikara (256460)

“…<p>(A) Nuclear run-on assays in THP-1 cells (2×10⁷) showed that CO represses IL-1β transcription by almost 98% within 30 min of LPS stimulation (p = 0.001) and the effect decreased to 67% at 60 min (p = 0.01). …”

Time-dependent changes of LC3, Beclin 1 and p62 expression in the penumbra following ischemia. by Li Gao (131516)

“…The expression of p62 decreased significantly at 6 h and lasted until 48 h, with a maximum reduction at 24 h postischemia. …”

<i>mPINC</i> expression declines during lactogenic hormone induced differentiation of HC11 cells. by Amy N. Shore (148122)

“…Data are presented as mean ± SEM (n = 3). (A) qPCR shows <i>mPINC1.0</i> and <i>mPINC1.6</i> expression decreases following 24 and 72 hrs of hormone treatment. …”

Analyses of GC and GS levels in the cortex and liver by LC/MS. by Ying Sun (23237)

“…<p>(A) Cortex GC and GS levels in IFG treated 4L;C* did not show significant reduction relative to the untreated mice. …”

Sertraline inhibits depression-like behavior and plasma Hcy content in CUMS rats. by Shen Chengfeng (640478)

“…<p>Sucrose preference, open field test scores, 5-HT level in the hippocampus and total plasma Hcy were measured as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0106625#pone-0106625-g001" target="_blank">Figure 1</a>. …”

DHA treatment and genotype modulate active properties of EC deep layer neurons. by Dany Arsenault (229311)

“…<p>(A, B) Examples of recording trace showing voltage response to a 3-s depolarizing current at the excitation threshold (top trace) and 80±5 pA above the rheobase (bottom trace) from the same neuron of each group. …”

High frequency power can predict neuronal cell type from single spikes. by Corey J. Keller (2625202)

“…Two channels were used for the training set. D) <i>Top panel</i>: Mean waveform traces extracted from time periods where the ratio of power in the high (3000-3500Hz) to low (500-600Hz) frequency bands were increased (red trace) and decreased (blue trace) as classified by the method illustrated in (C). …”

Table 1_The sound of complaints.docx by Maël Mauchand (21758654)

“…<p>Complaining is a social act in which a speaker often verbally conveys feelings of suffering to gain empathy from listeners. …”

Photomicrographs depicting typical regions of analysis for the NAc core, shell, dorsolateral striatum (DLS) and dorsomedial striatum (DMS). by Jing Li (10611)

“…Data are expressed as mean ± S.E.M. * <i>p</i><0.05, *** <i>p</i><0.001 indicates a significant difference from ethanol naïve; # <i>p</i><0.05, ## <i>p</i><0.01 indicates a significant difference from sham. …”

Expression of CD27 on lymphocytes isolated from various tissues of rhesus macaques detected by flow cytometry. by Chanjuan Shen (700402)

“…<p>(A) Representative plots generated from whole blood samples showing gating strategy for analysis of CD27+ lymphocytes isolated from all tissues. …”

An <i>Smc1b</i> hypomorphic mutation affects synapsis and recombination. by Brenda Murdoch (47263)

“…(B) Similarly, mean genome-wide MLH1 values ± SE were markedly decreased in homozygotes (20.7.9±0.21) by comparison with controls and heterozygotes (27.3±0.32 and 26.5±0.33, respectively) (F = 118.2; <i>p</i><0.0001). …”