Characterization of Genome-Wide Association-Identified Variants for Atrial Fibrillation in African Americans by Jessica T. Delaney (181642)

“…<div><h3>Background</h3><p>Despite a greater burden of risk factors, atrial fibrillation (AF) is less common among African Americans than European-descent populations. …”

DataSheet6_Single-cell transcriptome dynamics of the autotaxin-lysophosphatidic acid axis during muscle regeneration reveal proliferative effects in mesenchymal fibro-adipogenic pr... by Osvaldo Contreras (780538)

“…<p>Lysophosphatidic acid is a growth factor-like bioactive phospholipid recognising LPA receptors and mediating signalling pathways that regulate embryonic development, wound healing, carcinogenesis, and fibrosis, via effects on cell migration, proliferation and differentiation. …”

<i>osk</i> mRNA is reduced in <i>cup</i> mutants while Osk protein levels remain the same as in wild type. by Li Chin Wong (193882)

“…<p>(A) <i>osk</i> mRNA levels in pre-vitellogenic wild type ovaries and in ovaries from the three <i>cup</i> alleles, <i>cup⁸</i>, <i>cup³</i> and <i>cup¹³⁵⁵</i>, were measured by quantitative real time RT-PCR using <i>actin</i> mRNA as the control. …”

Image_2_Longitudinal Changes in Diffusion Tensor Imaging Following Mild Traumatic Brain Injury and Correlation With Outcome.tif by Bo Yin (681235)

“…Neuroimaging was obtained within 7 days post-injury for acute scans and repeated at 1 and 3 months post-injury. Using a region-of-interest-based approach, tract-based spatial statistics was used to conduct voxel-wise analysis on diffusion changes in mTBI and was compared to those of healthy matched controls, scanned during the same time period and rescanned with an interval similar to that of patients. …”

Table_2_From numbers to medical knowledge: harnessing combinatorial data patterns to predict COVID-19 resource needs and distinguish patient subsets.DOCX by Parthkumar H. Satashia (17354863)

“…New methods could also identify, upon admission, a subset of COVID-19 patients that reveal inflammation. …”

Data Sheet 2_Neonatal encephalopathy due to birth asphyxia and trauma: global trends and disparities.zip by Fengling Du (22229149)

“…Background<p>Neonatal encephalopathy due to birth asphyxia and trauma (NE-BAT) is a leading cause of neonatal mortality and long-term neurodevelopmental disabilities, particularly in low- and middle-income regions.…”

Data_Sheet_1_Alteration of pro-carcinogenic gut microbiota is associated with clear cell renal cell carcinoma tumorigenesis.docx by Bo-Yu Yang (12267206)

“…Here we aim to elucidate the association of specific gut bacteria and their metabolites with ccRCC.</p>Methods<p>In a pilot case-control study among 30 ccRCC patients (RCC group) and 30 healthy controls (Control group), 16S ribosomal RNA (rRNA) gene sequencing were analyzed from fecal samples collected prior to surgery or hospitalization. …”

Table5_Correlation Between Immune-Related Genes and Tumor-Infiltrating Immune Cells With the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer.XLSX by Yan Zhou (6523)

“…Among the many biomarkers predicting the efficacy of NAC, immune-related biomarkers, such as immune-related genes and tumor-infiltrating lymphocytes (TILs), play a key role.</p><p>Methods: We analyzed gene expression from several datasets in the Gene Expression Omnibus (GEO) database and evaluated the relative proportion of immune cells using the CIBERSORT method. …”

Table_2_The Impact of Chronic Heat Stress on the Growth, Survival, Feeding, and Differential Gene Expression in the Sea Urchin Strongylocentrotus intermedius.DOC by Yaoyao Zhan (359351)

“…Further Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways analyses revealed that these DEGs mainly enriched the functional categories of ribosome, protein processing in endoplasmic reticulum, and prion diseases. A total of 732 temperature-induced expressed genes, such as ATP5, heat shock protein 70, and heat shock protein 90, were identified as candidates that were closely correlated with heat resistance in S. intermedius. …”

DataSheet1_Huang Lian Jie Du decoction attenuated colitis via suppressing the macrophage Csf1r/Src pathway and modulating gut microbiota.docx by Shan Su (745649)

“…Introduction<p>Ulcerative colitis, a subtype of chronic inflammatory bowel disease (IBD), is characterized by relapsing colonic inflammation and ulcers. …”

Image_2_Splenic SUMO1 controls systemic inflammation in experimental sepsis.jpeg by Ayman Youssef (16537653)

“…In the spleen, endotoxemia induced a distinct temporal and substrate specificity for SUMO1 and SUMO2/3, and both were inhibited by TAK981. …”

Image_5_Insights Into the MYB-Related Transcription Factors Involved in Regulating Floral Aroma Synthesis in Sweet Osmanthus.JPEG by Xin Yan (17064)

“…In this study, we conducted a genome-wide analysis of MYB-related proteins in sweet osmanthus; 212 OfMYB-related TFs were divided into three distinct subgroups based on the phylogenetic analysis. …”

Table 1_The interaction between temperature and rainfall determines the probability of tropical forest fire occurrence in Hainan Island.docx by Xiaohua Chen (257762)

“…This study integrated ground-based fire statistics from the Hainan Forestry Department and moderate resolution imaging spectroradiometer (MODIS) fire point data to create a highly accurate forest fire dataset for Hainan Island, spanning 20 years (2000–2020). …”

DataSheet_1_The value of metabolic LncRNAs in predicting prognosis and immunotherapy efficacy of gastric cancer.xlsx by Peizhun Du (14324136)

“…Introduction<p>As a unique feature of malignant tumors, abnormal metabolism can regulate the immune microenvironment of tumors. …”

DataSheet_1_3D printed Ti-5Cu alloy accelerates osteogenic differentiation of MC3T3-E1 cells by stimulating the M2 phenotype polarization of macrophages.docx by Xin Zhao (71840)

“…In this study, we prepared Ti-5Cu alloy by three-dimensional printing technology and found that Ti-5Cu alloy presented a much smoother surface compared with Ti. In addition, the CCK-8 results indicated the Ti-5Cu alloy had no cytotoxicity to RAW264.7 cells by co-culture. …”

<b>Type 1 diabetes depends on CD4-driven expression of the transcriptional repressor, </b><b><i>Bcl6</i></b> by Dudley H. McNitt (20208081)

“…These data highlight BCL6 as a novel therapeutic target in type 1 diabetes.</p>…”

Image_1_Intracellular Complement Component 3 Attenuated Ischemia-Reperfusion Injury in the Isolated Buffer-Perfused Mouse Heart and Is Associated With Improved Metabolic Homeostasi... by M-K. Torp (12332864)

Table_1_Modulation of Fermentation Quality and Metabolome in Co-ensiling of Sesbania cannabina and Sweet Sorghum by Lactic Acid Bacterial Inoculants.docx by Tianqi Xia (5558435)

“…<p>Sesbania cannabina (SC) is a protein-rich roughage that thrives under moderate-severe saline-alkali (MSSA) soils with the potential to relieve the shortage of high nutritive forage. …”

DataSheet1_Cardioprotective and hypotensive mechanistic insights of hydroethanolic extract of Cucumis melo L. kernels in isoprenaline-induced cardiotoxicity based on metabolomics a... by Muqeet Wahid (17862647)

“…<p>Background: Cardiovascular diseases (CVD) continue to threaten health worldwide, and account for a significant portion of deaths and illnesses. …”

Table_1_Echocardiographic Prediction of Left Ventricular Dysfunction After Transcatheter Patent Ductus Arteriosus Closure in Children.DOCX by Miao Hou (340226)

“…</p><p>Conclusion: Transcatheter closure of PDA causes a significant deterioration in LV systolic function early after PDA closure, which recovered completely within 3 months of post-closure in children. …”