Characterisation of Genome-Wide PLZF/RARA Target Genes by Salvatore Spicuglia (204765)

“…We identify 413 specific PLZF/RARA target genes including a number encoding transcription factors involved in the regulation of haematopoiesis. …”

Table_8_Mendelian randomization in blood metabolites identifies triglycerides and fatty acids saturation level as associated traits linked to pancreatitis risk.xlsx by Jiarui Mi (11170284)

“…</p>Results<p>In the primary analysis with 249 traits, we found that plasma triglycerides were positively associated with pancreatitis risk. Intriguingly, a large number of traits associated with saturation or unsaturation of fatty acids also demonstrated causal associations. …”

DataSheet_4_Melatonin Attenuates Sepsis-Induced Small-Intestine Injury by Upregulating SIRT3-Mediated Oxidative-Stress Inhibition, Mitochondrial Protection, and Autophagy Induction... by Siqi Xu (429196)

“…We confirmed this mechanistic effect in a CLP-induced sepsis model of intestinal SIRT3 conditional-knockout mice, and found that melatonin preserved mitochondrial function and induced autophagy of small-intestine epithelial cells; these effects were dependent on SIRT3 activation. …”

UCP-1 expression in primary cultured brown adipocytes by G-CSF via p38 MAPK pathway. by Yonggu Lee (436856)

“…<p>(A) Oil red-O staining for brown adipocytes; (B) Indictors for differentiation of brown adipocytes. …”

DataSheet_7_SCM-198 Prevents Endometriosis by Reversing Low Autophagy of Endometrial Stromal Cell via Balancing ERα and PR Signals.zip by Yi-Kong Lin (12882812)

“…</p>Results<p>Increased estrogen-estrogen receptor (ER) α signaling and decreased progesterone receptor isoform B (PRB) expression synergistically led to a hypo-autophagy state in eESCs, which further inhibited the apoptosis of eESCs. …”

Image_2_Hypoxia-Inducible Factor 1α and 2α Have Beneficial Effects in Remote Ischemic Preconditioning Against Stroke by Modulating Inflammatory Responses in Aged Rats.TIF by Xiangnan Du (8552319)

“…ACF also reversed the activation of the Akt signaling pathway induced by RIPC following stroke. HIF may play a key role in RIPC, which was likely mediated by the Akt signaling pathway and systemic modulation of the inflammatory response in aged rats.…”

DataSheet_5_Melatonin Attenuates Sepsis-Induced Small-Intestine Injury by Upregulating SIRT3-Mediated Oxidative-Stress Inhibition, Mitochondrial Protection, and Autophagy Induction... by Siqi Xu (429196)

“…We confirmed this mechanistic effect in a CLP-induced sepsis model of intestinal SIRT3 conditional-knockout mice, and found that melatonin preserved mitochondrial function and induced autophagy of small-intestine epithelial cells; these effects were dependent on SIRT3 activation. …”

Table_1_Changes in the Microbial Community Structure and Soil Chemical Properties of Vertisols Under Different Cropping Systems in Northern China.docx by Xiuli Song (5955851)

“…The FS had high microbial diversity, with high relative abundances of Bacteroidetes and Zygomycota and a significantly lower relative abundance of Actinobacteria. …”

Image_2_Peri-interventional Triple Therapy With Dabigatran Improves Vasomotion and Promotes Endothelialization in Porcine Coronary Stenting Model.TIF by Rayyan Hemetsberger (5056196)

“…<p>Objective: We evaluated the short and long-term effect of peri-interventional dabigatran therapy on vasomotion, endothelialization, and neointimal formation in a porcine coronary artery stenting model.</p><p>Background: Stenting of coronary arteries induces local inflammation, impairs vasomotion and delays endothelialization.…”

Image 2_Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus.pdf by Guanfei Zhao (3815596)

“…CD8⁺ T naïve (Tn) cell MMP-Low, CD8⁺ T effector memory cell MMP-Low, CD8⁺ T central memory (Tcm) cell MMP-Low, and SCMM-CD8⁺ Tn cells demonstrated a moderate diagnostic value for SLE, with an area under the curve (AUC) above 0.8. …”

ABL Tyrosine Kinase Inhibition Variable Effects on the Invasive Properties of Different Triple Negative Breast Cancer Cell Lines by Clément Chevalier (251823)

“…ABL inhibition by the tyrosine kinase inhibitor nilotinib is a first-line treatment for this disease. Recently, ABL has also been implicated in the transforming properties of solid tumors, including triple negative (TN) breast cancer. …”

Supplementary Material for: Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovar... by Zuo T. (4522528)

“…<b><i>Background/Aims:</i></b> Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women, and it is usually characterized by chronic inflammation, oxidative stress, and altered microRNA expression. …”

Differential effects of Losartan and Atorvastatin in partial and full thickness burn wounds by Johanneke J. Akershoek (4110016)

“…Treatment with Losartan and to a lesser extent the combination therapy resulted in diminished graft take, increased wound contraction and poorer scar outcome. …”

Table_1_LncRNA TCF7 Promotes Epithelial Ovarian Cancer Viability, Mobility and Stemness via Regulating ITGB8.docx by Changlei Su (11717234)

“…It also correlates with advanced tumor features and poor prognosis in EOC, implying its potential as a target for EOC treatment.</p>…”

Data_Sheet_1_Pectin supplement alleviates gut injury potentially through improving gut microbiota community in piglets.ZIP by Guoqi Dang (14239187)

“…<p>As pectin is widely used as a food and feed additive due to its tremendous prebiotic potentials for gut health. …”

Image_2_Immunogenicity of SARS-CoV-2 mRNA intramuscular vaccination in patients with muscular disorders.jpeg by Ryousuke Kasai (14577584)

“…</p>Conclusion<p>Intensity and latency of antibody response were suppressed in patients with MDs. Although MDs may be a key contributor in predicting the antibody response to SARS-CoV-2 vaccination, SARS-CoV-2 immunization in MDs needs extensive research.…”

Table 2_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.xlsx by Yiwen Li (354034)

“…PI3K signaling pathway was identified as a central mediator of the microbiota interaction in DMIRI. …”

Table_8_Integrative Analysis of LGR5/6 Gene Variants, Gut Microbiota Composition and Osteoporosis Risk in Elderly Population.DOCX by Dong-sheng Di (11634688)

“…The rs10920362 CT/TT genotype associated with a decreased relative abundance of Actinobacteria (β = −1.32, P < 0.001), Bifidobacteriaceae (β = −1.70, P < 0.001), and Bifidobacterium (β = −1.70, P < 0.001) compared to the CC genotype.…”

image_2_Calcium-Sensing Receptor Participates in High Glucose-Induced EndMT in Primary Human Aortic Endothelial Cells.jpeg by Cheng Yuan (160315)

“…The in vitro results showed that HG significantly inhibited the expression of CD31 and increased FSP1 and α-SMA in a concentration- and time-dependent manner. Moreover, CaSR was increased in HAECs after HG treatment. …”

DataSheet_2_The value of metabolic LncRNAs in predicting prognosis and immunotherapy efficacy of gastric cancer.docx by Peizhun Du (14324136)

“…Introduction<p>As a unique feature of malignant tumors, abnormal metabolism can regulate the immune microenvironment of tumors. …”