M₁/M₄‑Preferring Muscarinic Cholinergic Receptor Agonist Xanomeline Reverses Wake and Arousal Deficits in Nonpathologically Aged Mice by Jason K. Russell (14467955)

“…The purpose of the present study was to provide the first assessment of the effects of the direct-acting M₁/M₄-preferring muscarinic cholinergic receptor agonist xanomeline on sleep/wake architecture and arousal in young and nonpathologically aged mice, in comparison with the AChEI donepezil, when dosed in either the active or inactive phase of the circadian cycle. Xanomeline produced a robust reversal of both wake fragmentation and disruptions in arousal when dosed in the active phase of nonpathologically aged mice. …”

Table1_Insulin-like peptide 8 (Ilp8) regulates female fecundity in flies.XLSX by Haomiao Li (2743693)

“…</p><p>Discussion: Our findings support a universal role of insect Ilp8 in female fecundity, and also provide novel clues for understanding the modes of action of Ilp8.…”

Data_Sheet_1_Effect of the Boron Concentration in Irrigation Water on the Elemental Composition of Edible Parts of Tomato, Green Bean, Potato, and Cabbage Grown on Soils With Diffe... by Márk Rékási (10966542)

“…The data on the effect of B on the elemental composition in the edible parts of vegetables are scarce. A greenhouse pot experiment investigated the effect of irrigation water containing 0.1 and 0.5 mg/L B on the biomass, elemental (e.g., B, Mg, K, Fe, Cu, and Zn) composition, and photosynthetic parameters of tomato (Solanum lycopersicum), green bean (Phaseolus vulgaris), potato (Solanum tuberosum), and cabbage (Brassica oleracea) plants grown on 10 kg of sand, silty sand, or silty soil. …”

The effects of pravastatin on the normal human placenta: Lessons from <i>ex-vivo</i> models by Adelina Balan (3749380)

“…This data is reassuring and important for clinicians that consider the treatment of high-risk patients with pravastatin, a treatment that exposes some normal pregnancies to the drug.…”

Table3_Insulin-like peptide 8 (Ilp8) regulates female fecundity in flies.XLS by Haomiao Li (2743693)

“…</p><p>Discussion: Our findings support a universal role of insect Ilp8 in female fecundity, and also provide novel clues for understanding the modes of action of Ilp8.…”

Image_4_Modulation of intestinal IL-37 expression and its impact on the epithelial innate immune response and barrier integrity.tif by Laura Kröhn (17011479)

“…However, higher IL37 expression correlated with a reduced proinflammatory cytokine response in murine colonic organoids. …”

DataSheet1_Degradation of 17 Benzodiazepines by the UV/H2O2 Treatment.docx by Wen-Dan You (11579059)

“…The degradation of alprazolam, a typical benzodiazepine, during the UV/H₂O₂ treatment was increased with the increasing H₂O₂ dosage. …”

Role of SIRT-2 in the endotoxin tolerant RAW cells. by Xianfeng Wang (120153)

“…<p><u>A: RAW cells undergo endotoxin tolerance as early as 4h after LPS stimulation:</u> To study endotoxin tolerance in RAW cells, we stimulated cells with LPS (100ng/ml) and re-stimulated with another LPS challenge (100ng/ml) at 0, 4, 6, 8, and 24 hour time points for four hour. …”

Table 1_Alterations in sulcal depth and associated functional connectivity in schizophrenia with auditory verbal hallucinations.docx by Zhenru Guo (21811247)

“…Sulcal depth may represent a promising biomarker for early diagnosis.</p>…”

Image1_Ablation Patterns of the Debris Covered Tongue of Halong Glacier Revealed by Short Term Unmanned Aerial Vehicle Surveys.jpeg by Wanqin Guo (450937)

“…The surface ablation rates show a clear negative exponential relationship with the measured debris thicknesses, well in accordance with previous studies. …”

DataSheet_1_The Protective Effect of Magnesium Lithospermate B on Hepatic Ischemia/Reperfusion via Inhibiting the Jak2/Stat3 Signaling Pathway.pdf by Ning Zhang (23771)

“…Second, we investigated the protein level of p-Jak2/Jak2 and p-Stat3/Stat3 using Western blotting and found that MLB could significantly inhibit the activation of the Jak2/Stat3 signaling pathway, which was further verified by AG490 in a mouse model. Finally, the effect of MLB on the Jak2/Stat3 pathway was further assessed in an in vitro model of RAW 264.7 cells; 1 µg/ml LPS induced the secretion of inflammatory mediators, including IL-6, TNF-α, and activation of the Jak2/Stat3 signaling pathway. …”

Reactive Organic Gases from Vehicle Evaporative Emissions: Rates, Compositions, and Temperature Effects by Jun Lu (36049)

“…This study quantifies evaporative volatile organic compound emissions from China 3 to China 6 standard vehicles using a variable temperature sealed housing evaporative determination system. …”

Image1_HR-MS Based Untargeted Lipidomics Reveals Characteristic Lipid Signatures of Wilson’s Disease.TIF by Yixiao Zhi (11736269)

“…<p>Background and Aims: The diagnosis of Wilson’s disease (WD) is challenging by clinical or genetic criteria. A typical early pathological change of WD is the increased liver lipid deposition and lowered serum triglyceride (TG). …”

DataSheet1_SOCS3 is Related to Cell Proliferation in Neuronal Tissue: An Integrated Analysis of Bioinformatics and Experiments.docx by Yeuni Yu (8951993)

“…Gliomas are subdivided according to a combination of microscopic morphological, molecular, and genetic factors. …”

Data_Sheet_1_Insights Into the MYB-Related Transcription Factors Involved in Regulating Floral Aroma Synthesis in Sweet Osmanthus.FASTA by Xin Yan (17064)

“…In this study, we conducted a genome-wide analysis of MYB-related proteins in sweet osmanthus; 212 OfMYB-related TFs were divided into three distinct subgroups based on the phylogenetic analysis. …”

Image_5_Wheat F-box Protein TaFBA1 Positively Regulates Plant Drought Tolerance but Negatively Regulates Stomatal Closure.tif by Jie An (543888)

“…In addition, TaFBA1 was found to be a negative regulator of ABA-induced stoma movement; mRNA transcription of certain ABA signaling-related genes was lower in TaFBA1 OE plants than in WT plants following ABA treatment. …”

Effects of three sesquiterpene compounds from volatile oil of <i>Dalbergia odorifera</i> T. Chen on pERK1/2, ERK1/2, PPARγ and HO-1 expression in LPS-stimulated RAW264.7 macrophage... by Xiang Li (114679)

“…<p>(A). LPS co-incubation induced significant increase of pERK1/2 expression, the ratio of pERK1/2 to ERK1/2 was higher than that in the control group (*<i>p</i><0.05). 50 µM ENL attenuated the increased ratio of pERK1/2 to ERK1/2, while 50 µM SDL suppressed this ratio compared to LPS treated alone (#<i>p</i><0.05), and RDL had no effect on the increased ratio. …”

Table 4_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.xlsx by Zhuowen Hu (20431616)

“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”

DataSheet2_Lateral impact response of circular hollow steel tubes with mid-span localized penetrating notches.docx by Xiaoli Huang (309237)

“…The results showed that under a lateral impact load, the mid-span of the CHST column presented global bending failure patterns accompanied by local indentation deformation in the impact region and local buckling deformation at the bottom of the fixed end. …”

Data_Sheet_1_RETRACTED: Endothelial-Monocyte Activating Polypeptide II Suppresses the In Vitro Glioblastoma-Induced Angiogenesis by Inducing Autophagy.DOCX by Zhiqing Li (174007)

“…<p>The obstacle in delivering therapeutics to glioblastoma (GBM) is tumor-induced angiogenesis which leads to the formation of abnormal vessels and a dysfunctional blood-tumor barrier. Here, we elucidated the effect of endothelial-monocyte activating polypeptide II (EMAP II) on the GBM-induced angiogenesis as well as its potential mechanisms. …”