Image_2_Longitudinal Cytokine Profile in Patients With Mild to Critical COVID-19.tif by Lowell Ling (8433594)

“…The secondary objective was to assess the associations between cytokines and clinical endpoints in critically ill patients. A total of 40 adult patients (mild = 8, moderate = 15, severe/critical = 17) hospitalized with COVID-19 were included in this study. …”

Data_Sheet_1_Macrophages-Related Genes Biomarkers in the Deterioration of Atherosclerosis.docx by Yue Zheng (601811)

“…The hub DEMRGs and their interactions were analyzed using NetworkAnalyst 3.0 and for validation, the expressions of hub DEMRGs were analyzed using the GSE135055 and GSE116250 datasets as well as atherosclerosis and MI mice model.</p>Results<p>A total of 509 differentially expressed genes (DEGs) were correlated with the abundance of macrophages and were identified as DEMRGs (Pearson correlation coefficients (PCC) > 0.6), which were mainly enriched in extracellular structure organization, lysosomal membrane, MHC protein complex binding, and so on. …”

Image_1_Effects of Coix Seed Extract, Bifidobacterium BPL1, and Their Combination on the Glycolipid Metabolism in Obese Mice.tif by Wei Zhang (405)

“…Male C57BL/6J mice were fed a high-fat diet for 8 weeks to establish an obesity model. …”

Seq and cell summary. by Xiaoke Xu (3468623)

“…This infection can lead to neurological effects and establish a viral reservoir. Given the gaps in our understanding of how these cells respond <i>in vivo</i> to acute CNS infection, we conducted single-cell RNA sequencing (scRNA-seq) on myeloid cells from the brains of three rhesus macaques 12 days after SIV infection, along with three uninfected controls. …”

Image_5_Global, regional, and national years lived with disability due to blindness and vision loss from 1990 to 2019: Findings from the Global Burden of Disease Study 2019.TIF by Shasha Li (139491)

“…Purpose<p>This study aimed to provide a comprehensive assessment of burden estimates and the secular trend of blindness and vision loss, as measured by years lived with disability (YLDs), at the global, regional, and national levels.…”

Mode of action of the antimicrobial peptide Mel4 is independent of <i>Staphylococcus aureus</i> cell membrane permeability by Muhammad Yasir (3555896)

“…<div><p>Mel4 is a novel cationic peptide with potent activity against Gram-positive bacteria. …”

Table3_Placental circadian lincRNAs and spontaneous preterm birth.xlsx by Guoli Zhou (225819)

“…<p>Long non-coding RNAs (lncRNAs) have a much higher cell- and/or tissue-specificity compared to mRNAs in most cases, making them excellent candidates for therapeutic applications to reduce off-target effects. …”

Liraglutide Increases FGF-21 Activity and Insulin Sensitivity in High Fat Diet and Adiponectin Knockdown Induced Insulin Resistance by Mengliu Yang (120445)

“…<div><h3>Background</h3><p>Liraglutide is a glucagon-like peptide-1 analogue that stimulates insulin secretion and improves β-cell function. …”

Experimental timeline overview. by Leriana Garcia Reis (12646978)

“…Our previous analysis of these mice found HF diet decreased number of pups born, but increased litter growth rate to postnatal (PN) d12. …”

S2 Raw data - by Fang Xu (138747)

“…</p><p>Conclusion</p><p>Our results demonstrated that ononin may ameliorate cartilage damage and inflammatory response in OA rats by downgrading MAPK and NF-κB pathways, thus identifying ononin as a potential novel drug to treat OA.</p></div>…”

Prevalence of SARS-CoV-2 antibodies among Belgian nursing home residents and staff during the primary COVID-19 vaccination campaign by Eline Meyers (14183825)

“…Sampling occurred between 1 February and 24 March 2021, in a randomly sampled population that received none, one or two BNT162b2 vaccine doses.…”

Image 1_Increases in the susceptibility of human endometrial CD4+ T cells to HIV-1 infection post-menopause are not dependent on greater viral receptor expression frequency.jpeg by Landon G. vom Steeg (13794506)

“…Here, we evaluated how menopause-associated changes in CD4⁺ T cell numbers and subsets as well as HIV coreceptor expression, particularly CCR5, in the endometrium (EM), endocervix (CX), and ectocervix (ECX) may alter HIV infection susceptibility. Using a tissue-specific mixed cell infection model, we demonstrate that while no changes in CD14⁺ macrophage infection susceptibility were observed, CD4⁺ T cell HIV-1 infection frequency increases following menopause in the EM, but not CX nor ECX. …”

Table5_α-Mangostin Alleviated HIF-1α-Mediated Angiogenesis in Rats With Adjuvant-Induced Arthritis by Suppressing Aerobic Glycolysis.XLSX by Tian-Tian Jiang (11857058)

“…<p>A previously validated anti-rheumatic compound α-mangostin (MAN) shows significant metabolism regulatory effects. …”

Increased Thymic Cell Turnover under Boron Stress May Bypass TLR3/4 Pathway in African Ostrich by Hai-bo Huang (751364)

“…<div><p>Previous studies revealed that thymus is a targeted immune organ in malnutrition, and high-boron stress is harmful for immune organs. …”

Table_3_Preliminary prediction of semen quality based on modifiable lifestyle factors by using the XGBoost algorithm.docx by Mingjuan Zhou (12880019)

“…Then, machine learning with the XGBoost algorithm was applied to establish a primary prediction model by using the collected data. …”

Demographic characteristics of the two groups. by Tao Yuan (443733)

“…This study aimed to examine the effects of kinesio taping (KT) on lower limb biomechanical characteristics during the Y-balance anterior reach task in individuals with CAI.</p><p>Methods</p><p>A total of 30 participants were recruited, comprising 15 individuals with CAI and 15 healthy controls. …”

Image_1_The Impact of BKI-1294 Therapy in Mice Infected With the Apicomplexan Parasite Neospora caninum and Re-infected During Pregnancy.TIFF by Pablo Winzer (544721)

“…In this study, mice were first vaccinated with a sublethal dose of N. caninum tachyzoites and were treated with BKI-1294. …”

Image4_Comprehensive analysis of m7G modification patterns based on potential m7G regulators and tumor microenvironment infiltration characterization in lung adenocarcinoma.TIF by Shouzheng Ma (12264398)

“…Nonetheless, the potential regulatory role of N7-methylguanosine (m⁷G) modification in shaping and impacting the TME remains unclear.</p><p>Methods: A comprehensive analysis was performed to explore the m⁷G modification patterns based on 24 potential m⁷G regulators in 817 lung adenocarcinoma (LUAD) patients, and the TME landscape in distinct m⁷G modification patterns were evaluated. …”

Data_Sheet_2_Global, Regional, and National Burden of Cancer in Children Younger Than 5 Years, 1990–2019: Analysis of the Global Burden of Disease Study 2019.docx by Hui-Ming Ren (12898484)

“…Although all of the SDI regions displayed a steady drop in deaths and DALYs between 1990 and 2019, the low-middle and low SDI regions showed increasing trends of incidence and prevalence. …”

P1^SCSMV directly binds to the stem-loop region of <i>NbbZIP60U</i> through via NLS region <i>in vitro</i>. by Kun Zhang (108291)

“…<p><b>(A).</b> CBB staining of the purified recombinant GST-tagged GFP, P1^SCSMV, and P1^SCSMV-nls mutant. …”