Image_1_OCT4 and SOX2 Specific Cytotoxic T Cells Exhibit Not Only Good Efficiency but Also Synergize PD-1 Inhibitor (Nivolumab) in Treating Breast Cancer Stem-Like Cells and Drug-R... by Wei Peng (432211)

“…Besides, PD-1 inhibitor (nivolumab) improved the cytotoxic activity of OCT4&SOX2 CTLs against MCF7-BCSCs in a dose-dependent manner. In vivo, OCT4&SOX2 CTLs plus PD-1 inhibitor (nivolumab) decreased tumor volume and tumor weight while increased tumor apoptosis rate compared to OCT4&SOX2 CTLs alone, PD-1 inhibitor (nivolumab) alone, and control.…”

MicroRNA-145 Regulates Human Corneal Epithelial Differentiation by Sharon Ka-Wai Lee (216835)

“…Global gene expression was analyzed using Agilent Whole Human Genome Oligo Microarray and GeneSpring GX11.0. With a 5-fold difference compared to cells with scrambled sequences, miR-145 up-regulated 324 genes (containing genes for immune response) and down-regulated 277 genes (containing genes for epithelial development and stem cell maintenance). …”

DataSheet_1_LIM1 contributes to the malignant potential of endometrial cancer.pdf by Hiroaki Kato (446108)

“…Among the identified genes, KM plotter analysis showed that high LIM1 expression was associated with a significantly poorer prognosis in EC. Additionally, LIM1 expression was significantly higher in high-grade EC cell lines, HEC50B cells than Ishikawa cells. …”

Table_3_Hepatoma-Derived Growth Factor and DDX5 Promote Carcinogenesis and Progression of Endometrial Cancer by Activating β-Catenin.xls by Chunhua Liu (502032)

“…Immunohistochemistry analysis showed that high expression of DDX5 constituted an unfavorable factor with respect to the clinicopathological characteristics of EC tissues and that HDGF and DDX5 high expression (HDGF+/DDX5+) led to a worse prognosis for patients with EC (P < 0.001). …”

Image1_Transition of dome formation to sudden explosive eruptions at Popocatépetl, Mexico: magnetic indicators.TIF by Ana Lillian Martin-Del-Pozzo (18854692)

“…Some of the domes behaved as contained lava flows within the crater floor (pancakes) while others were more irregular-shaped. Activity decreased considerably over this 2019 interval except for the unexpected explosions in March and June, that produced ash plumes reaching up to 14,000 m a.s.l. …”

Image1_Protective effects of YCHD on the autoimmune hepatitis mice model induced by Ad-CYP2D6 through modulating the Th1/Treg ratio and intestinal flora.tif by Jiawen Wu (63886)

“…Background<p>Autoimmune hepatitis (AIH) is a chronic liver inflammatory disease mediated by autoimmune reactions, the pathogenesis of AIH is probably related to the imbalance of intestinal flora. …”

Table_1_Sex differences in heart failure patients assessed by combined echocardiographic and cardiopulmonary exercise testing.docx by Zach Rozenbaum (5367935)

“…Females diagnosed with HFpEF showed attenuated increases in end diastolic volume index (P = 0.040 for sex × time interaction), significantly elevated E/e' (P < 0.001), significantly decreased left ventricle (LV) end diastolic volume:E/e ratio (P = 0.040 for sex × time interaction), and lesser increases in A-VO₂ difference (P = 0.003 for sex × time interaction), comparing to males with HFpEF. …”

Image5_Interleukin 9 mediates T follicular helper cell activation to promote antibody responses.jpeg by Taiki Sato (394623)

“…Accumulating evidence indicates a crucial role for interleukin-9 (IL-9) in the formation of germinal centers (GCs), enhancing the generation of class-switched high-affinity antibodies. …”

Table_1_Metagenome Analysis of Intestinal Bacteria in Healthy People, Patients With Inflammatory Bowel Disease and Colorectal Cancer.xlsx by Yongshun Ma (9737837)

“…Objectives<p>Several reports suggesting that the intestinal microbiome plays a key role in the development of inflammatory bowel disease (IBD) or colorectal cancer (CRC), but the changes of intestinal bacteria in healthy people, patients with IBD and CRC are not fully explained. …”

Measures of inflammatory markers following immunization with either vehicle or DS-01. by Pavel V. Belichenko (778408)

“…<p>(A) Confocal images of GFAP (left) and CD45 immunoreactivity (right) in vehicle- and DS-01 treated 2N and Ts65Dn mice. …”

Video_5_Murine Metatarsus Bone and Joint Collagen-I Fiber Morphologies and Networks Studied With SHG Multiphoton Imaging.AVI by Martin Vielreicher (10957656)

“…Multiphoton Second Harmonic Generation (SHG) microscopy, is able to visualize the sterical topology of the collagen-I fibrillar network in 3D, in a minimally invasive and label-free manner. Penetration depths exceed those of conventional visible light imaging and can be further optimized through employing decalcification or optical clearing processing ex vivo. …”

Interleukin-18 Down-Regulates Multidrug Resistance-Associated Protein 2 Expression through Farnesoid X Receptor Associated with Nuclear Factor Kappa B and Yin Yang 1 in Human Hepat... by Xiao-cong Liu (785281)

“…We found that expression of MRP2 was repressed by IL-18 at both the mRNA and protein levels in a dose- and time-dependent manner. Furthermore, the activated NF-κB pathway increased YY1 and reduced FXR. …”

DataSheet_1_Exosomal RNA Expression Profiles and Their Prediction Performance in Patients With Gestational Diabetes Mellitus and Macrosomia.docx by Yingdi Yuan (12452193)

“…Logistic regression, receiver operating characteristic (ROC) curves, and graphical nomogram were applied to evaluate the performance of exosomal RNA (in peripheral blood) in macrosomia prediction.</p>Results<p>A total of 98 mRNAs, 372 lncRNAs, and 452 circRNAs were differentially expressed in cord blood exosomes from patients with GDM-M. …”

Nitrate and Ammonium Contribute to the Distinct Nitrogen Metabolism of <i>Populus simonii</i> during Moderate Salt Stress by Sen Meng (640516)

“…<div><p>Soil salinity is a major abiotic stressor affecting plant growth. …”

Properties of OCAM KO neurospheres. by Loïc Deleyrolle (720967)

“…<p>(<b><i>A</i></b>): Immunofluorescence detection of OCAM in KO and WT embryonic spinal cord neurospheres. …”

Image_5_Single cell analysis of short-term dry eye induced changes in cornea immune cell populations.jpg by Jehan Alam (5577734)

“…Significant changes in expression of 1,365 genes (adj p < 0.0001) were noted in rMP with increases in cytokines and chemokines (Tnf, Cxcl1, Ccl12, Il1rn), inflammatory markers (Vcam, Adam17, Junb), the TAM receptor (Mertk), and decreases in complement and MHCII genes. A differentiation trajectory from monocytes to terminal state rMP was found. …”

Table_12_Physio-biochemical and transcriptomic analysis of Bacillus amyloliquefaciens PG-4-induced salt stress tolerance in Macrotyloma uniflorum.DOCX by Yanna Wu (7675676)

“…</p>Results<p>In presence of different salt levels, PG-4 showed a high potentiality to produce several plant growth promoting metabolites such as NH₃, siderophore, 1-aminocyclopropane-1-carboxylic acid deaminase (ACC-deaminase), and hydrolytic enzymes. …”

Image_7_Implication of Melanopsin and Trigeminal Neural Pathways in Blue Light Photosensitivity in vivo.TIF by Veronika Marek (6725135)

“…The only drug that significantly decreased the blue-light aversion was the intraperitoneally injected melanopsin antagonist. …”

Image_1_Implication of Melanopsin and Trigeminal Neural Pathways in Blue Light Photosensitivity in vivo.TIF by Veronika Marek (6725135)

“…The only drug that significantly decreased the blue-light aversion was the intraperitoneally injected melanopsin antagonist. …”

DataSheet_1_Increased Circulating Cell-Free DNA in Eosinophilic Granulomatosis With Polyangiitis: Implications for Eosinophil Extracellular Traps and Immunothrombosis.docx by Teppei Hashimoto (4996412)

“…The structure of EETs showed bolder net-like chromatin threads in vitro and EETs showed greater stability against DNase than NETs. EETs provided a scaffold for platelet adhesion.</p>Conclusion<p>cfDNA was increased in EGPA, associated with disease activity. …”