Mutational landscape of TCL cell lines. by Rufino Mondejar (4025846)

Genes in the DNA damage-induced response pathway are downregulated in Siomycin A-treated GSCs. by Mutsuko Minata (553095)

“…Expression of FOXM1, MELK, Aurora A/B, and Survivin were significantly decreased by Siomycin A treatment compared with DMSO treatment.…”

Microarray assay identifies involvement of an Act1--PI3K IB subunit (PI3K-cat gamma) pathway in IL-17A-mediated signaling cascades. by Xiaoqin Guo (527376)

“…<p>(A) Gene chip assay identifies multiple genes differentially expressed in Act1 knock down and control HT-29 cells. …”

Additional representations of the protocol B template CoMFA model for carbonic anhydrase II. by Richard D. Cramer (753796)

“…<p>The upper panel shows the conventional “stdev*coeff” representation of a CoMFA model: the green shapes enclose spatial regions where affinity increases with steric bulk; the yellow shapes enclose regions where decreased steric bulk improves affinity; the red shapes enclose regions where more positive electrostatic potential improves affinity; the blue shapes enclose regions where more negative electrostatic potential improves affinity. …”

Image_1_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.JPEG by Wen-I Liao (586146)

“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”

Image_8_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.JPEG by Wen-I Liao (586146)

“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”

Image_4_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.JPEG by Wen-I Liao (586146)

“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”

N⁶-methyladenosine-dependent primary microRNA-126 processing activated PI3K-AKT-mTOR pathway drove the development of pulmonary fibrosis induced by nanoscale carbon blac... by Bin Han (45760)

“…We found that both of m⁶A modifications of pri-miRNA-126 and its binding with DGCR8 were decreased after CB treatment, which resulted in the reduction of mature miRNA-126 accompanied by accumulation of unprocessed pri-miRNA-126. …”

Table_1_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.DOCX by Wen-I Liao (586146)

“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”

Image_6_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.JPEG by Wen-I Liao (586146)

“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”

Image_7_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.JPEG by Wen-I Liao (586146)

“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”

Image_5_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.TIF by Wen-I Liao (586146)

“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”

Image_3_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.TIF by Wen-I Liao (586146)

“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”

Image_2_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.JPEG by Wen-I Liao (586146)

“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”

DataSheet_2_Immunotherapeutic Effects of Different Doses of Mycobacterium tuberculosis ag85a/b DNA Vaccine Delivered by Electroporation.pdf by Yan Liang (139654)

“…</p>Results<p>Compared with the phosphate-buffered saline (PBS) group, the CD4⁺IFN-γ⁺ T cells% in whole blood from 200 µg DNA IM group and four DNA EP groups increased significantly (P<0.05), CD8⁺IFN-γ⁺ T cells% (in 200 μg DNA EP group), CD4⁺IL-4⁺ T cells% (50 μg DNA IM group) and CD8⁺IL-4⁺ T cells% (50 μg and 100 μg DNA IM group, 100 μg and 200 μg DNA EP group) increased significantly only in a few DNA groups (P< 0.05). The CD4⁺CD25⁺ Treg cells% decreased significantly in all DNA vaccine groups (P<0.01). …”

DataSheet_1_Immunotherapeutic Effects of Different Doses of Mycobacterium tuberculosis ag85a/b DNA Vaccine Delivered by Electroporation.pdf by Yan Liang (139654)

“…</p>Results<p>Compared with the phosphate-buffered saline (PBS) group, the CD4⁺IFN-γ⁺ T cells% in whole blood from 200 µg DNA IM group and four DNA EP groups increased significantly (P<0.05), CD8⁺IFN-γ⁺ T cells% (in 200 μg DNA EP group), CD4⁺IL-4⁺ T cells% (50 μg DNA IM group) and CD8⁺IL-4⁺ T cells% (50 μg and 100 μg DNA IM group, 100 μg and 200 μg DNA EP group) increased significantly only in a few DNA groups (P< 0.05). The CD4⁺CD25⁺ Treg cells% decreased significantly in all DNA vaccine groups (P<0.01). …”

Relative abundance of (A) <i>Hypocreales</i>, (B), <i>Aspergillus</i>, (C) <i>Malasseziales</i>, and (D) Cladosporium identified in the synovial fluid of RA patients and healthy co... by Dargham Bayan Mohsen Hammad (7907630)

“…<p>Data determined by the amplification and sequencing of the ITS2 gene. (A) The relative abundance of order <i>Hypocreales</i> was increased in synovial fluid of RA patients relative to healthy control synovial fluid. …”

DataSheet_1_RelA Is an Essential Target for Enhancing Cellular Responses to the DNA Repair/Ref-1 Redox Signaling Protein and Restoring Perturbated Cellular Redox Homeostasis in Mou... by Mahmut Mijit (12283736)

“…Gene expression analysis demonstrated that Ref-1 inhibitors significantly decreased IL-8, FOSB, and c-Jun when functional RelA is present. …”

Data_Sheet_1_Non-canonical Interaction Between O-Linked N-Acetylglucosamine Transferase and miR-146a-5p Aggravates High Glucose-Induced Endothelial Inflammation.PDF by Wan-Yu Lo (444892)

“…Real time PCR analysis found that miR-146a-5p was decreased in HG- and glucosamine-stimulated HAECs. …”

Serum LRG levels in patients with DM-IP and the HC, and changes in serum LRG levels at baseline measurement and at 2, 4, and 8 weeks after the initiation of treatment. by Takaaki Ishida (525804)

“…<p>The serum LRG levels of the DM-IP patients were higher than those of the HC (A). The serum LRG levels at 2, 4, and 8 weeks after the initiation of treatment were significantly decreased in comparison with those before treatment (B). …”