Regulation of endogenous p42.3 expression by miR-29a. by Yun Cui (342642)

“…The expression levels of p42.3 and cyclin B1 protein decreased significantly after MKN-45 cells were treated with si-p42.3 or miR-29a mimics while the level of CHK2 protein increased dramatically. …”

RAINFALL REGIME ON FINE ROOT GROWTH IN A SEASONALLY DRY TROPICAL FOREST by EUNICE MAIA DE ANDRADE (4894216)

“…Considering the concerns about the resilience of SDTF to climate changes, the objective of this study was to evaluate the effect of the rainfall regime on fine root growth in a SDTF. The experiment started at the end of the wet season (July 2015), when fine roots were evaluated and ingrowth cores were implemented. …”

miR-29a modulates neuronal differentiation of MSCs by targeting REST. by Ping Duan (312653)

“…<p>(A) Lentiviral infection of miR-29a inhibitor decreases miR-29a expression in MSCs. …”

SCN to EEG: a graphic summary of the NTP model for NREM sleep structure. by Helli Merica (208808)

“…The box for the S-P population is in grayscale to indicate that the vertical axis is different from that of the colored patterns following: it indicates the fraction of neurons in each equivalent firing-rate mode (β, σ and δ) corresponding to the cascade (relatively silent→moderate firing-rate→fast firing-rate) rather than the cascade (fast firing-rate→moderate firing-rate→relatively silent) in the colored patterns. Thus the mean firing-rate in the S-P population (grayscale) progressively increases with time, while in the W-P population (colour) it decreases.…”

Effects of isobavachalcone treatment on BV-2 cells and Neuro-2a cells. by Haoran Jing (3621779)

“…C: Isobavachalcone decreased microglial-induced neuro-2a death in a co-culture system. …”

Inc exhibits key properties of a Cul3 adaptor in neurons in vivo. by Qiuling Li (390393)

“…<p><b>(A)</b> Co-immunoprecipitation of 3×FLAG-Inc and 3×FLAG-3×HA-Cul3 from male whole animal lysates. …”

Description of the role of the pharmacist in a multiprofessional team focused on the care of hospitalized elderly by Isabela Vaz Leite Pinto (12817700)

“…Twenty one (87.5%) patients required pharmaceutical interventions and 20 (83.3%) required pharmaceutical interventions by the physician. A total of 163 pharmaceutical interventions were carried out, representing a mean of 6.79 interventions/patient and 82.2% acceptance. …”

(A,B) Time (C,D) and memory required to run the whole pipeline. by Alex Váradi (11508172)

“…Using more threads decreased the running time proportionally. On the left plots (A,C) the size of symbols is proportional to the reference genome size. …”

Underfeeding during the early postnatal period induces a permanent growth delay. by Lyvianne Decourtye (3633343)

“…Moreover, this was associated with a non—significant tendency of decreased expression levels of GHRH receptor (GHRH-R) (<b>G</b>) (n = 5 per group), and of GH (<b>H</b>) (n = 5–7 per group) in 10 day-old underfed male pups. …”

Increased MMAB level in mitochondria as a novel biomarker of hepatotoxicity induced by Efavirenz by Zhimi Tan (4633714)

“…Finally, knockdown of MMAB by shRNA induced increases in the β-Alanine (β-Ala) production levels and decrease in ALDH3A2 expression.</p><p>Conclusions</p><p>A mitochondrial proteomic study was performed to study the proteins related to EFV-inducted liver toxicity. …”

Identification of PFD0495c as a candidate gene linked to sphingolipid synthesis. by Pamela A. Tamez (222157)

“…(ii) Dendrogram of microarray data sets from two biological replicates showing that of the five conserved genes of the Hiller secretome validated to be exported <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000118#ppat.1000118-vanOoij1" target="_blank">[15]</a>, only two are regulated by PPMP: 3-fold increase in PFD0495c(**), 2-fold decrease in PFC0435w(*). …”

Development of a novel bioreactor and systems for suspension cell culture in biopharmaceutical production by Rajesh Sharma (6183845)

“…The heat flow data (metabolic heat) from the treated and normal cells showed a distinct decrease in the heat generation profile which indicated that the treated cells were viable but not as active as the normal (non-treated) cells. …”

The DNA methyltransferase DNMT3A contributes to autophagy long-term memory by Patricia González-Rodríguez (760839)

“…In fact, DNA-methylation mediated by <i>de novo</i> DNA methyltransferase DNMT3A of <i>MAP1LC3</i> loci upon autophagy stimulation leads to the observed long-term decrease of <i>MAP1LC3</i> isoforms at transcriptional level. …”

Overdiagnosis and overtreatment of thyroid cancer: A population-based temporal trend study by Sabrina Jegerlehner (4110049)

“…The mortality slightly decreased. These findings suggest that a substantial and growing part of the detected thyroid cancers are overdiagnosed and overtreated.…”

Metformin reduces ECM remodeling, EMT, and metastasis in a PDAC mouse model. by Joao Incio (834672)

“…<p>(A) Expression of genes associated with extra-cellular matrix (ECM) remodeling, epithelial-to-mesenchymal transition (EMT) and inflammation in AK4.4 tumors from control and metformin-treated mice. …”

Structure–Activity Relationship of Antischistosomal Ozonide Carboxylic Acids by Jianbo Wu (165270)

“…It was possible to increase solubility, decrease protein binding, and maintain the high antischistosomal activity in mice infected with juvenile and adult Schistosoma mansoni by incorporating a weak base functional group in these compounds. …”

File S1 - Increase in Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) Had a Strong Impact on the Development of Type 2 Diabetes in Japanese Individuals with Impaired I... by Akiko Morimoto (623003)

“…<p><b>Combined supporting information file. Table S1. ORs for the development of type 2 diabetes according to baseline IIS status and another category of ΔHOMA-IR (decrease, ≤−0.20; stable, ±0.19; moderate increase, 0.20–0.39; and large increase, ≥0.40).…”

Number of subjects in each slope/speed class. by Arthur H. Dewolf (4537918)

Migration assay wound closure following transfection with pre-miR-21 is consistent with control results. by Sara E. Martin del Campo (683602)

Raman spectra of myelin sheath of sciatic nerve fiber. by Natalia N. Rodionova (4452793)