The effects of metformin, donepezil, insulin glargine, and glibenclamide on serum biomarkers: Glucose, HbA1c, lipid profile, IL6, TNFa, amyloid β 42, total plasma tau, and NFL. by Shatw Khalid Ali (13020885)

Subjects:

The transcriptional activity of hepatocyte nuclear factor 4 alpha is inhibited <i>via</i> phosphorylation by ERK1/2 by Borbála Vető (3429854)

“…In addition, 24-hour activation of the pathway further decreased HNF4α chromatin binding to specific loci in ChIP-qPCR experiments, which confirms the previous reports on the decreased expression of the <i>HNF4a</i> gene due to ERK1/2 activation. …”

Establishing a cost-per-result of laboratory-based, reflex Cryptococcal antigenaemia screening (CrAg) in HIV+ patients with CD4 counts less than 100 cells/μl using a Lateral Flow A... by Naseem Cassim (671952)

“…One-way sensitivity analyses including increasing or decreasing test volumes by 60% revealed a cost-per-result range of $3.84 to $6.03.…”

Fold binding force (A, B, C) and total binding events (D, E, F) of perlecan domain IV (A, D), laminin (B, E), and fibronectin (C, F) attached to an AFM tip engaged to either LNECFP... by Keith H. Jansson (571788)

“…<p><b>A</b>. When the AFM tip is coated with perlecan domain IV, vector control 2BECFP cells exhibit a 40% decrease in binding force relative to LNECFP cells (top panel, P<0.05), and sustain nearly 700 less binding events than their LNECFP counterparts (bottom panel). …”

Impact of lean manufacturing tools on maintenance management at a manufacturing plant in the Western Cape by Gershwin Cornelius (20719184)

“…By proper utilisation of these lean tools, organisations can increase productivity via understanding the lean tools and with corrective actions which do not include hefty machine investments</p><p dir="ltr">The primary research objectives of this study are the following:</p><p dir="ltr">• To determine if a common trend between MTTR and OEE within a manufacturing plant in the Western Cape</p><p dir="ltr">• To determine whether an increase in MTTR results in a decrease in OEE within a manufacturing plant in the Western Cape.…”

Steady-state fluorescence studies provide additional support to the A region Model 3. by Sylvain Maenner (255271)

“…<p>In (A, B, and C), the binding sites of oligonucleotides P1 to P6 used in the FRET experiments are shown for the three 2-D structures of the A region corresponding to Models 1, 2, and 3. …”

Supplementary Material for: Arteriovenous Access Monitoring with Ultrasound Dilution in a Pediatric Hemodialysis Unit by Ashoor I.F. (4149550)

“…<b><i>Conclusions:</i></b> A noninvasive UD screening algorithm of AV access flow is very sensitive in detecting hemodynamically significant stenosis and can decrease AV access thrombosis rates.…”

Electrochemistry as a Complementary Technique for Revealing the Influence of Reducing Agent Concentration on AgNPs. by Sapokazi Timakwe (14127576)

“…This process ended up in the formation of large aggregates that decrease the active surface area and therefore result in a significant decrease in their unique properties. …”

Effect of Si sources and Si application methods on (a) shoot fresh weight (g), (b) shoot dry weight (g), (c) root fresh weight (g), and (d) root dry weight (g) of maize. by Inzamam Ul Haq (11668620)

Data_Sheet_1_Functional characterization of Vibrio alginolyticus T3SS regulator ExsA and evaluation of its mutant as a live attenuated vaccine candidate in zebrafish (Danio rerio)... by Weijie Zhang (145595)

“…Besides, the ΔexsA showed a weakened swarming phenotype and an ~100-fold decrease in virulence to zebrafish. …”

Mutations Affecting Potassium Import Restore the Viability of the <i>Escherichia coli</i> DNA Polymerase III <i>holD</i> Mutant by Adeline Durand (2294566)

“…These findings show that the Δ<i>holD</i> mutant is rescued by a decrease in K⁺ import. The effect of <i>trk</i> inactivation is additive with the previously identified Δ<i>holD</i> suppressor mutation <i>lexAind</i> that blocks the SOS response indicating an SOS-independent mechanism of suppression. …”

<i>N</i>⁶-methyladenosine modification and the YTHDF2 reader protein play cell type specific roles in lytic viral gene expression during Kaposi's sarcoma-associated herp... by Charles R. Hesser (5147309)

“…Transcriptome-wide m⁶A-sequencing of the KSHV-positive renal carcinoma cell line iSLK.219 during lytic reactivation revealed the presence of m⁶A across multiple kinetic classes of viral transcripts, and a concomitant decrease in m⁶A levels across much of the host transcriptome. …”

Oral administration of <i>Lactobacillus paracasei</i> L9 attenuates PM_2.5-induced enhancement of airway hyperresponsiveness and allergic airway response in murine model... by Xifan Wang (1741579)

“…<div><p>This study investigated allergy immunotherapy potential of <i>Lactobacillus paracasei</i> L9 to prevent or mitigate the particulate matter 2.5 (PM_2.5) enhanced pre-existing asthma in mice. Firstly, we used a mouse model of asthma (a 21-day ovalbumin (OVA) sensitization and challenge model) followed by PM_2.5 exposure twice on the same day of the last challenge. …”

Immunohistochemical (IHC) staining for MMP11 and PYGL reveals changes consistent with the transcriptomic biomarker. by Elizabeth S. Borden (18983447)

“…<b>(A)</b> BN with uniform strong staining of nevus melanocytes in the epidermis and a staining gradient in the dermis with a progressive decrease in staining deeper in the dermis. …”

Alternate Wetting and Drying Limits Arsenic in Porewater and Rice Grain under Severe Future Climate Conditions by Aria H. Duncan (22445853)

“…Grain total As concentrations decreased by 1.5× with AWD under a 33 °C climate and by 1.3× under a 38 °C climate. …”

Alternate Wetting and Drying Limits Arsenic in Porewater and Rice Grain under Severe Future Climate Conditions by Aria H. Duncan (22445853)

“…Grain total As concentrations decreased by 1.5× with AWD under a 33 °C climate and by 1.3× under a 38 °C climate. …”

Alternate Wetting and Drying Limits Arsenic in Porewater and Rice Grain under Severe Future Climate Conditions by Aria H. Duncan (22445853)

“…Grain total As concentrations decreased by 1.5× with AWD under a 33 °C climate and by 1.3× under a 38 °C climate. …”

Alternate Wetting and Drying Limits Arsenic in Porewater and Rice Grain under Severe Future Climate Conditions by Aria H. Duncan (22445853)

“…Grain total As concentrations decreased by 1.5× with AWD under a 33 °C climate and by 1.3× under a 38 °C climate. …”

Alternate Wetting and Drying Limits Arsenic in Porewater and Rice Grain under Severe Future Climate Conditions by Aria H. Duncan (22445853)

“…Grain total As concentrations decreased by 1.5× with AWD under a 33 °C climate and by 1.3× under a 38 °C climate. …”

Alternate Wetting and Drying Limits Arsenic in Porewater and Rice Grain under Severe Future Climate Conditions by Aria H. Duncan (22445853)

“…Grain total As concentrations decreased by 1.5× with AWD under a 33 °C climate and by 1.3× under a 38 °C climate. …”