Nuclear translocation of Atox1 potentiates activin A-induced cell migration and colony formation in colon cancer by Arundhati Jana (157555)

“…<div><p>Background</p><p>Colorectal cancer remains a deadly cancer due to metastatic disease. To understand the molecular mechanisms of metastasis in colon cancer, we investigated whether the copper chaperone antioxidant-1 (Atox1) protein plays a role in this process. …”

image_2_Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics.jpeg by Shao Thing Teoh (5297732)

“…We found that sialic acid metabolism is upregulated in highly metastatic breast tumors. Knocking out a key gene in sialic acid metabolism, Cmas, inhibits synthesis of the activated form of sialic acid, cytidine monophosphate-sialic acid and decreases the formation of lung metastases in vivo. …”

Raw data for Figure 3B: Mesoangioblasts and HIDEMs suppress T cell proliferation in a dose dependent manner by Ou Li (101542)

Table_2_Efficacy and Safety of Faecal Microbiota Transplantation for Acute Pancreatitis: A Randomised, Controlled Study.DOC by Ling Ding (302098)

“…Eligible participants were randomly assigned to receive faecal transplant (n = 30) or normal saline (n = 30) via a nasoduodenal tube once and then again 2 days later. …”

ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer by Tom G. Keulers (4804599)

“…Besides oxygen, delivery of glucose was hampered in hypoxic regions <i>in vivo</i>, which increases the reliance of cells on other carbon sources (e.g., L-glutamine). We observed decreased intracellular L-glutamine levels in ATG12-deficient cells during hypoxia and increased cell killing after L-glutamine depletion, indicating a central role for ATG12 in maintaining L-glutamine homeostasis. …”

Data_Sheet_1_Altered Vascular Adaptations to Pregnancy in a Rat Model of Advanced Maternal Age.pdf by Mazhar Pasha (11197767)

“…We previously demonstrated vascular dysfunction and abnormal pregnancy outcomes in a rat model of advanced maternal age. However, vascular adaptations to pregnancy in aging were not studied. …”

Alcohol consumption and survival after breast cancer diagnosis in Japanese women: A prospective patient cohort study by Yuko Minami (7861412)

“…In the Cox model, ever-drinking was associated with a decreased risk of all-cause (HR: 0.75; 95% CI: 0.54–1.05) and breast cancer-specific death (HR: 0.68; 95% CI: 0.46–0.99). …”

image_8_Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics.jpeg by Shao Thing Teoh (5297732)

“…We found that sialic acid metabolism is upregulated in highly metastatic breast tumors. Knocking out a key gene in sialic acid metabolism, Cmas, inhibits synthesis of the activated form of sialic acid, cytidine monophosphate-sialic acid and decreases the formation of lung metastases in vivo. …”

image_9_Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics.jpeg by Shao Thing Teoh (5297732)

“…We found that sialic acid metabolism is upregulated in highly metastatic breast tumors. Knocking out a key gene in sialic acid metabolism, Cmas, inhibits synthesis of the activated form of sialic acid, cytidine monophosphate-sialic acid and decreases the formation of lung metastases in vivo. …”

Table_1_Efficacy and Safety of Faecal Microbiota Transplantation for Acute Pancreatitis: A Randomised, Controlled Study.DOCX by Ling Ding (302098)

“…Eligible participants were randomly assigned to receive faecal transplant (n = 30) or normal saline (n = 30) via a nasoduodenal tube once and then again 2 days later. …”

image_5_Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics.jpeg by Shao Thing Teoh (5297732)

“…We found that sialic acid metabolism is upregulated in highly metastatic breast tumors. Knocking out a key gene in sialic acid metabolism, Cmas, inhibits synthesis of the activated form of sialic acid, cytidine monophosphate-sialic acid and decreases the formation of lung metastases in vivo. …”

image_3_Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics.jpeg by Shao Thing Teoh (5297732)

“…We found that sialic acid metabolism is upregulated in highly metastatic breast tumors. Knocking out a key gene in sialic acid metabolism, Cmas, inhibits synthesis of the activated form of sialic acid, cytidine monophosphate-sialic acid and decreases the formation of lung metastases in vivo. …”

Video2_A platform for automated and label-free monitoring of morphological features and kinetics of spheroid fusion.AVI by Thomas Deckers (5465186)

“…For both cell pools, the technology was able to characterize the fusion rate and quality in an automated manner and allowed us to demonstrate that an increased chondrogenic maturity was linked with a decreased fusion rate. The platform is also applicable to other spheroid types, enabling an increased understanding of tissue fusion. …”

Video1_A platform for automated and label-free monitoring of morphological features and kinetics of spheroid fusion.AVI by Thomas Deckers (5465186)

“…For both cell pools, the technology was able to characterize the fusion rate and quality in an automated manner and allowed us to demonstrate that an increased chondrogenic maturity was linked with a decreased fusion rate. The platform is also applicable to other spheroid types, enabling an increased understanding of tissue fusion. …”

table_1_Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics.xlsx by Shao Thing Teoh (5297732)

“…We found that sialic acid metabolism is upregulated in highly metastatic breast tumors. Knocking out a key gene in sialic acid metabolism, Cmas, inhibits synthesis of the activated form of sialic acid, cytidine monophosphate-sialic acid and decreases the formation of lung metastases in vivo. …”

Video3_A platform for automated and label-free monitoring of morphological features and kinetics of spheroid fusion.AVI by Thomas Deckers (5465186)

“…For both cell pools, the technology was able to characterize the fusion rate and quality in an automated manner and allowed us to demonstrate that an increased chondrogenic maturity was linked with a decreased fusion rate. The platform is also applicable to other spheroid types, enabling an increased understanding of tissue fusion. …”

table_3_Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics.xlsx by Shao Thing Teoh (5297732)

“…We found that sialic acid metabolism is upregulated in highly metastatic breast tumors. Knocking out a key gene in sialic acid metabolism, Cmas, inhibits synthesis of the activated form of sialic acid, cytidine monophosphate-sialic acid and decreases the formation of lung metastases in vivo. …”

image_6_Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics.jpeg by Shao Thing Teoh (5297732)

“…We found that sialic acid metabolism is upregulated in highly metastatic breast tumors. Knocking out a key gene in sialic acid metabolism, Cmas, inhibits synthesis of the activated form of sialic acid, cytidine monophosphate-sialic acid and decreases the formation of lung metastases in vivo. …”

A Long-Term Assessment of the Variability in Winter Use of Dense Conifer Cover by Female White-Tailed Deer by Glenn D. DelGiudice (421270)

“…<div><p>Backgound</p><p>Long-term studies allow capture of a wide breadth of environmental variability and a broader context within which to maximize our understanding of relationships to specific aspects of wildlife behavior. …”

image_1_Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics.jpeg by Shao Thing Teoh (5297732)

“…We found that sialic acid metabolism is upregulated in highly metastatic breast tumors. Knocking out a key gene in sialic acid metabolism, Cmas, inhibits synthesis of the activated form of sialic acid, cytidine monophosphate-sialic acid and decreases the formation of lung metastases in vivo. …”