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largest decrease » largest decreases (Expand Search), larger decrease (Expand Search), marked decrease (Expand Search)
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226301
Study search and selection flow diagram.
Published 2024“…</p><p>Results</p><p>Our meta-analysis included a total of 12 studies. Overall analysis indicated that ICIs plus chemotherapy could significantly improve OS (HR = 0.79; 95% CI: 0.74–0.84; <i>I</i><sup>2</sup> = 44.4%, <i>P</i> = 0.055), PFS (HR = 0.62; 95% CI: 0.59–0.67; <i>I</i><sup>2</sup> = 75.3%, <i>P</i> = 0.000), and ORR (RR = 1.48; 95% CI: 1.27–1.73; <i>I</i><sup>2</sup> = 79.0%, <i>P</i> = 0.000) when compared to chemotherapy treatments. …”
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226302
DataSheet_3_Jianpi Huayu Decoction Attenuates the Immunosuppressive Status of H22 Hepatocellular Carcinoma-Bearing Mice: By Targeting Myeloid-Derived Suppressor Cells.pdf
Published 2020“…Therefore, that the proportion of CD11b<sup>+</sup>Gr-1<sup>+</sup> cells increased in the spleen of tumor-bearing hosts may not be villainy after treatment, when these drugs suppress the immunosuppressive ability of CD11b<sup>+</sup>Gr-1<sup>+</sup> cells and promote it mature to replenish dendritic cell, at the same time. Generally, JHD may be a complementary and alternative drug for attenuating the immunosuppressive status induced by hepatocellular carcinoma, possibly by promoting differentiation and inhibiting the immunosuppressive activity of MDSCs.…”
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226303
Table 8_Clinical effect of unilateral biportal minimally invasive surgery in the treatment of patients with spinal degenerative diseases based on intelligent multimodal reconstruct...
Published 2025“…Objective<p>To explore the effect of unilateral biportal minimally invasive surgery in the treatment of patients with spinal degenerative diseases based on intelligent multimodal reconstruction technology.</p>Methods<p>A total of 100 patients with spinal degenerative diseases treated with unilateral biportal endoscopy during 2023–2024 in Orthopedics Center of our hospital were selected as research objects. …”
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226304
Table 1_TLR4 and prostaglandin pathways at the crossroads of endotoxemia-induced lipolysis.docx
Published 2025“…LPS also increased the expression of EP2, a PGE<sub>2</sub> receptor, while simultaneously reducing EP4 content. …”
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226305
Band Gap Engineering and Trap Depths of Intrinsic Point Defects in RAlO<sub>3</sub> (R = Y, La, Gd, Yb, Lu) Perovskites
Published 2021“…Calculations of the trap depths performed within the super cell approach for a number of intrinsic point defects and their complexes allowed recognizing specific trapping centers that can be responsible for the observed TSL. …”
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226306
Presentation_4_Impact of BAFF Blockade on Inflammation, Germinal Center Reaction and Effector B-Cells During Acute SIV Infection.pptx
Published 2020“…From day 2 post-infection (dpi), Treated macaques received one weekly injection of BR3-Fc molecule, a soluble BAFF antagonist, for 4 weeks. Whereas, the kinetics of CD4<sup>+</sup> T-cell loss and plasma viral loads were comparable in both groups, BAFF blockade delayed the peak of inflammatory cytokines (CXCL10, IFNα), impaired the renewal of plasmacytoid dendritic cells and fostered the decline of plasma CXCL13 titers after 14 dpi. …”
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226307
Data file cross-sectional study.
Published 2024“…Here, we investigated innate cell populations hypothesized to play a role in these two faces of the disease, in an endemic population in Gabon.…”
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226308
Image 1_TLR4 and prostaglandin pathways at the crossroads of endotoxemia-induced lipolysis.jpeg
Published 2025“…LPS also increased the expression of EP2, a PGE<sub>2</sub> receptor, while simultaneously reducing EP4 content. …”
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226309
Admixture mapping of pelvic organ prolapse in African Americans from the Women’s Health Initiative Hormone Therapy trial
Published 2017“…This region includes <i>RGMA</i>, a potent regulator of the BMP family of genes. …”
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226310
Data_Sheet_1_Tilianin Extracted From Dracocephalum moldavica L. Induces Intrinsic Apoptosis and Drives Inflammatory Microenvironment Response on Pharyngeal Squamous Carcinoma Cells...
Published 2023“…Combined, these results showed that tilianin treatment increased cytotoxicity as well as the apoptotic population of FaDu cells in a dose-dependent manner. Furthermore, tilianin treatment decreased the level of anti-apoptotic markers Bcl-2 and Bcl-xL, increased the level of apoptotic factors Bad and Bax, and stimulated cytochrome c release, caspase-3 and poly ADP ribose polymerase (PARP) activation in FaDu cells. …”
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226311
Table_1_CD73 Rather Than CD39 Is Mainly Involved in Controlling Purinergic Signaling in Calcified Aortic Valve Disease.docx
Published 2019“…Overall, the data obtained demonstrated that purinergic signaling was involved in the pathogenesis of aortic stenosis and calcification potentially acting via various cell types, wherein among enzymes, degrading extracellular ATP CD73 rather than CD39 played a prominent role.</p>…”
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226312
Data_Sheet_1_Improved Relapse-Free Survival in Patients With High Natural Killer Cell Doses in Grafts and During Early Immune Reconstitution After Allogeneic Stem Cell Transplantat...
Published 2020“…The results suggest a protective effect of high doses of NK cells in grafts and during early immune reconstitution and support the perception of NK cells as innate effector cells with anti-tumor effects in the setting of allogeneic stem cell transplantation.…”
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226313
Table_1_SRSF1 acts as an IFN-I-regulated cellular dependency factor decisively affecting HIV-1 post-integration steps.xlsx
Published 2022“…Type I interferons (IFN-I) play a crucial role in the innate immunity against HIV-1 by inducing the expression of IFN-stimulated genes (ISGs) including potent host restriction factors. …”
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226314
H-Bonding Dependent Structures of (NH<sub>4</sub><sup>+</sup>)<sub>3</sub>H<sup>+</sup>(SO<sub>4</sub><sup>2-</sup>)<sub>2</sub>. Mechanisms of Phase Transitions
Published 2003“…According to <sup>1</sup>H MAS NMR obtained for phases II and III, the nature of the acidic proton disorder is dynamic, and localization of the proton takes place in a broader range of temperatures, as can be expected from the X-ray diffraction data.…”
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226315
Synthesis of Bis-β-Diketonate Lanthanide Complexes with an Azobenzene Bridge and Studies of Their Reversible Photo/Thermal Isomerization Properties
Published 2019“…The ligand, bis-β-diketone with an azobenzene bridge (4,4′-(4,4,4-trifluoro-1,3-butanedione)azobenzene, <b>H</b><sub><b>2</b></sub><b>L</b>), was prepared for the synthesis of a series of dinuclear lanthanide complexes with the formula <b>[Ln</b><sub><b>2</b></sub><b>L</b><sub><b>3</b></sub><b>(DMSO)</b><sub><b>4</b></sub><b>]</b> (Ln = Eu<sup>3+</sup>, Gd<sup>3+</sup>, Tb<sup>3+</sup>, and DMSO = dimethyl sulfoxide). …”
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226316
Lancelet Artemis participates in DNA hairpin resolution.
Published 2025“…<p><b>(A)</b> Schematic diagrams of the GFP reporter assays and PCR assays used to measure BbeRAG1L/2L-mediated TIR excision and recombination. …”
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226317
mGluR-interacting domains on PrP<sup>C</sup>.
Published 2017“…<p><b>(A)</b> Brain homogenate from wild-type (C57BL/6J) and <i>Prnp</i><sup><i>o/o</i></sup> mice was subjected to immunoprecipitation by POM1 followed by immunoblotting using polyclonal anti-mGluR5 (right) or anti-mGluR1 (left) and anti-PrP<sup>C</sup> antibodies. …”
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226318
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226319
Video_12_Additional Improvement of Respiratory Technique on Vascular Function in Hypertensive Postmenopausal Women Following Yoga or Stretching Video Classes: The YOGINI Study.MOV
Published 2020“…</p><p>Study Design: Hypertensive postmenopausal women were recruited and randomized for 12 weeks, twice a week, of supervised yoga or stretching video classes of 75 min for 12 weeks associated or not with respiratory technique. …”
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226320
Video_4_Additional Improvement of Respiratory Technique on Vascular Function in Hypertensive Postmenopausal Women Following Yoga or Stretching Video Classes: The YOGINI Study.MOV
Published 2020“…</p><p>Study Design: Hypertensive postmenopausal women were recruited and randomized for 12 weeks, twice a week, of supervised yoga or stretching video classes of 75 min for 12 weeks associated or not with respiratory technique. …”