Novel DNA Aptamer for CYP24A1 Inhibition with Enhanced Antiproliferative Activity in Cancer Cells by Madhu Biyani (12427332)

“…Overexpression of the vitamin D3-inactivating enzyme CYP24A1 (cytochrome P450 family 24 subfamily and hereafter referred to as CYP24) can cause chronic kidney diseases, osteoporosis, and several types of cancers. …”

In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway by Kuttikrishnan, Shilpa

“…FOXM1 and BUB1B expression exhibited a dose-dependent reduction in NSP-B-treated CTCL cells.FOXM1 silencing decreased cell viability and increased apoptosis via BUB1B downregulation. …”
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Inactivation of <i>Francisella tularensis</i> Gene Encoding Putative ABC Transporter Has a Pleiotropic Effect upon Production of Various Glycoconjugates by Vera Dankova (1392487)

“…In contrast to <i>ΔpglA</i>, inactivation of <i>FTS_1402</i> had a pleiotropic effect, leading to alteration in glycosylation and, importantly, to decrease in lipopolysaccharide, capsule, and/or capsule-like complex production, which were reflected by distinct phenotypes in host–pathogen associated properties and virulence potential of the two mutant strains. …”

Palladium(II), Platinum(II), and Iridium(I) Complexes of 2-Phosphino-1-dimethylaminoferrocenes: A Survey of Structure and Catalysis by Costa Metallinos (2328832)

“…The new complexes displayed a structural trend relating a decrease in heteroatom-metal bond length with an increase in ligand bite angle on going from Ir to Pd and Pt. …”

Image2_Uncovering structural variants associated with body weight and obesity risk in labrador retrievers: a genome-wide study.TIF by Michal Antkowiak (17011314)

“…Obesity status was based on a 5-point body condition score (BCS) and the obese dog group included all dogs with a BCS of 5, along with dogs with the highest body weight within the BCS 4 group. …”

Resistant parasites exhibit deficient binding and uptake of UDA-FITC. by Víctor M. Castillo-Acosta (699651)

“…B) Microscopy images of fixed cells showing the decrease in UDA-labeling of UDA15a and UDA15b cells in comparison to parental <i>T</i>. …”

Image1_Uncovering structural variants associated with body weight and obesity risk in labrador retrievers: a genome-wide study.TIF by Michal Antkowiak (17011314)

“…Obesity status was based on a 5-point body condition score (BCS) and the obese dog group included all dogs with a BCS of 5, along with dogs with the highest body weight within the BCS 4 group. …”

DICER+AGO2 enzymes cleave fluorogenic substrates into duplex products that are unstable at T>25°C. by Mark A. Bernard (608655)

“…<p>Enzymatic activity (37°C) is shown for the dsRNA DICER substrates (BoGD664AS * GD664S, <b>A</b>; BoGD664AS-dAdG * GD664S, <b>C</b>; BoPD664S * PD664AS, <b>E</b>; BoPD664S-dAdG * PD664AS, <b>G</b>) and fluorogenic siRNA BoPsi664 (BoPsi664S * Psi664AS; <b>I</b>) by AGO2 (120 nM) + DICER (30 nM) but not by <i>E</i>. …”

Inactivation of <i>Francisella tularensis</i> Gene Encoding Putative ABC Transporter Has a Pleiotropic Effect upon Production of Various Glycoconjugates by Vera Dankova (1392487)

“…In contrast to <i>ΔpglA</i>, inactivation of <i>FTS_1402</i> had a pleiotropic effect, leading to alteration in glycosylation and, importantly, to decrease in lipopolysaccharide, capsule, and/or capsule-like complex production, which were reflected by distinct phenotypes in host–pathogen associated properties and virulence potential of the two mutant strains. …”

Frequency of sexual activity and number of sexual partners based on erectile functioning (IIEF-5 score of 16 or less was a reference for erectile dysfunction). by Mikolaj Przydacz (3621878)

S1 Data - Prognostic nomogram integrated with inflammatory marker ratios for assessing in-hospital mortality risk in patients with acute type A aortic dissection by Xiao-Chai Lv (22378891)

Predicted plots of species that exhibited a change in detection rate between vegetation types or different trajectories over time within vegetation types. by Maldwyn John Evans (17061173)

Impact of the interaction between sewage pH and CPAM dosage on sewage turbidity. (a) Contour diagram; (b) 3D surface diagram. by Peng Zhao (128233)

The pathway analysis of 348 genes in the cytokine-cytokine receptor interaction pathway (Fig 6A) using the KEGG pathway database and DAVID software. by Souma Suzuki (18554923)

The global changes of prevalence (A-C), DALYs (D-F), and mortality (G-I) rates of IBD among WCBA from 1990 to 2021. by Jiefeng Zhao (9090305)

(A) Hypothetical model showing how the ERK-METTL3 axis suppresses α-herpesvirus proliferation through the antiviral innate immune pathway. by Lucai Wang (22050158)

Scatter plots of photo score by ColorDx green cone score (A), red cone score (B), and blue cone score (C). by Richard C. Trevino (22676460)

Feeds composition and nutritional value of the diet fed to Nellore steers with and without access to shade finished in feedlot during spring in a tropical environment. by M. Jordana Rivero (14610947)

Impact of group 1 and group 2 drugs on hyperglycemia based on HbA1c levels before and after 3 months of administration. by Nadia Gul (249538)

Summary of subgroup analysis results. by Junyin Pan (20700411)

“…The results showed that dietary anthocyanins significantly improved various lipid and glycemic markers:</p><p>HDL-C: increased by 0.05 mmol/L (95% CI: 0.01 to 0.10, p = 0.026), LDL-C: decreased by 0.18 mmol/L (95% CI: -0.28 to -0.08, p = 0.000), Triglycerides (TGs): reduced by 0.11 mmol/L (95% CI: -0.20 to -0.02, p = 0.021), Total cholesterol (TC): lowered by 0.34 mmol/L (95% CI: -0.49 to -0.18, p = 0.000), Fasting blood glucose (FBG): reduced by 0.29 mmol/L (95% CI: -0.46 to -0.12, p = 0.001), Glycated hemoglobin (HbA1c): decreased by 0.43% (95% CI: -0.74 to -0.13, p = 0.005). …”