Data_Sheet_1_Low Bone Mineral Density in Hemophiliacs.PDF by Jennifer Gebetsberger (3364280)

“…</p>Conclusion<p>Understanding the role of factor VIII and the mechanisms of decreased bone mineral density in hemophilia A is critically important, especially as non-factor replacement therapies are available, and treatment decisions potentially impact bone health.…”

High-performance thin-layer chromatogram of mouse brain ganglioside distribution in control (Ctl 1, Ctl 2) and experimental (VCS, #8566, #8568) brain tissue. by Jay S. Schneider (671374)

“…Note the increase in GM1 in VCS animals and decreased GD1a, GT1a, GT1b, and GQ1b, in striatal (CD) and hippocampus (HP) samples.…”

Kaplan-Meier graph illustrating cardiovascular mortality in the study population with ischemic heart disease, in those supplemented with selenium and coenzyme Q10 versus placebo du... by Urban Alehagen (796660)

Comparison of patients' immune status between SD and PD. by Yasuki Hijikata (4729446)

“…. *, paired t test; **, unpaired t test. (<b>A</b>) The frequency of peripheral blood Tregs in patients with SD decreased significantly after systemic CPA administration and this treatment (p = 0.0098 on day 6 and p = 0.041 on day 49). …”

Table_1_Case report: Mucous membrane pemphigoid with complicated autoantibody profile indicating the necessity of comprehensive diagnostic methods and the contribution of IgA autoa... by Weijun Liu (233776)

“…Compared with IgG autoantibodies, the levels of IgA autoantibodies against various autoantigens decreased more significantly with improvement of clinical features after the initiation of treatments. …”

Evaluation of retinal function and CLRN1-HA expression following subretinal delivery. by Astra Dinculescu (1807921)

“…<p>A. Bar graphs show the average maximum ERG b-wave amplitudes in scotopic, dark-adapted conditions of untreated wild-type control eyes, compared to AAV-treated eyes that received decreasing doses of AAV-CLRN1-HA vector (2 months post-injection). …”

MYCN protein partners identified in NB cells. by Zhihui Liu (95891)

“…We demonstrate that MYCN cooperates with WDR5 and G9a to orchestrate global gene transcription. The targeting of both these cofactors is a novel therapeutic strategy to indirectly target the oncogenic activity of <i>MYCN</i>.…”

Effect of apixaban on platelet and fibrin interactions with damaged vessels exposed to flowing blood. by Gines Escolar (310448)

“…The size of platelet aggregates was apparently decreased in samples exposed to apixaban. (<b>C</b>) Activated and non activated prothrombin complex concentrates, aPCCs and PCCs, restored levels of fibrin deposited on the subendothelium. …”

Altered vesicular cargo composition in enriched fractions of <i>Rabgef1-KO</i> retina. by Passley Hargrove-Grimes (9915365)

“…<p>(A) Summary of proteins identified from mass spectrometric analysis of vesicle enriched sub-cellular fractions from control and <i>Rabgef1</i>^<i>-/-</i> retina. …”

Video_4_Defective Neutrophil Transendothelial Migration and Lateral Motility in ARPC1B Deficiency Under Flow Conditions.mp4 by Lanette Kempers (10899027)

“…Here we show that under physiological flow conditions human ARPC1B-deficient neutrophils were able to transmigrate through TNF-α-pre-activated endothelial cells with a decreased efficiency and, once transmigrated, showed definite impairment in subendothelial crawling. …”

Video_3_Defective Neutrophil Transendothelial Migration and Lateral Motility in ARPC1B Deficiency Under Flow Conditions.mp4 by Lanette Kempers (10899027)

“…Here we show that under physiological flow conditions human ARPC1B-deficient neutrophils were able to transmigrate through TNF-α-pre-activated endothelial cells with a decreased efficiency and, once transmigrated, showed definite impairment in subendothelial crawling. …”

Image_1_Defective Neutrophil Transendothelial Migration and Lateral Motility in ARPC1B Deficiency Under Flow Conditions.tif by Lanette Kempers (10899027)

“…Here we show that under physiological flow conditions human ARPC1B-deficient neutrophils were able to transmigrate through TNF-α-pre-activated endothelial cells with a decreased efficiency and, once transmigrated, showed definite impairment in subendothelial crawling. …”

Video_1_Defective Neutrophil Transendothelial Migration and Lateral Motility in ARPC1B Deficiency Under Flow Conditions.mp4 by Lanette Kempers (10899027)

“…Here we show that under physiological flow conditions human ARPC1B-deficient neutrophils were able to transmigrate through TNF-α-pre-activated endothelial cells with a decreased efficiency and, once transmigrated, showed definite impairment in subendothelial crawling. …”

Image_2_Defective Neutrophil Transendothelial Migration and Lateral Motility in ARPC1B Deficiency Under Flow Conditions.tif by Lanette Kempers (10899027)

“…Here we show that under physiological flow conditions human ARPC1B-deficient neutrophils were able to transmigrate through TNF-α-pre-activated endothelial cells with a decreased efficiency and, once transmigrated, showed definite impairment in subendothelial crawling. …”

ODE modeling of WNT5A-EGF/AR signaling and experimental validation. by Zhiwei Ji (493628)

“…<p>(<b>A)</b> The effect of WNT5A on 22RV1 cell viability. …”

Video_2_Defective Neutrophil Transendothelial Migration and Lateral Motility in ARPC1B Deficiency Under Flow Conditions.mp4 by Lanette Kempers (10899027)

“…Here we show that under physiological flow conditions human ARPC1B-deficient neutrophils were able to transmigrate through TNF-α-pre-activated endothelial cells with a decreased efficiency and, once transmigrated, showed definite impairment in subendothelial crawling. …”

Immune pathways in <i>Ae</i>. <i>aegypti</i> mosquitoes infected by DENV. by Ju-Mei Wang (6589220)

“…<p><b>A</b>, Heatmap of transcriptional variation in expression of immune-related genes (ROS pathways and AMP genes) in DENV-infected mosquitoes. …”

Data_Sheet_1_The HDAC6 Inhibitor Trichostatin A Acetylates Microtubules and Protects Axons From Excitotoxin-Induced Degeneration in a Compartmented Culture Model.PDF by Kelsey Hanson (5147819)

“…While there were no changes to tyrosinated tubulin or MAP1B, acetylated tubulin was significantly (p < 0.05) decreased by 40% at 6 h post-treatment. To determine whether increasing microtubule acetylation prior to kainic acid exposure could prevent axon fragmentation, we investigated the effect of reducing microtubule deacetylation with the HDAC6 inhibitor, trichostatin A. …”

Rb and p53 Liver Functions Are Essential for Xenobiotic Metabolism and Tumor Suppression by Sathidpak Nantasanti (3181224)

“…We show that loss of Rb and p53 resulted in reduced Cyp3a expression decreased accumulation of protoporphyrin and consequently less ductular reaction in livers of mice fed with DDC for 3 weeks. …”

Image_9_Heat-Killed Lacticaseibacillus paracasei GMNL-653 Exerts Antiosteoporotic Effects by Restoring the Gut Microbiota Dysbiosis in Ovariectomized Mice.TIF by Jhih-Hua Jhong (4777659)

“…<p>Osteoporosis is a metabolic inflammatory disease, an imbalance occurs between bone resorption and formation, leading to bone loss. …”