Knockdown of endogenous Nischarin expression promotes neurite outgrowth in Neuro-2a cells. by Yuemin Ding (289067)

“…Nischarin expression was determined by real time quantitative RT-PCR <b>(A)</b> and western blot assay <b>(B)</b>. Expression of the Nischarin gene and protein after transfection with Nis-shRNA1-4 decreased to some degree. …”

<i>MIR376A</i> overexpression blocked autophagy in Huh-7 cells. by Gozde Korkmaz (498139)

“…(C) Overexpression of <i>MIR376A</i> resulted in decreased autophagic flux in Huh-7 cells. …”

Image_5_The Circumferential Resection Margin Is a Prognostic Predictor in Colon Cancer.TIFF by Xin-Yi Tang (9031154)

“…X-tile software identified 0 and 30 mm as optimal cutoff values (P < 0.001) for prognosis, which was applicable only in stage II–IV patients. A 20 and 33% risk decrease were observed in patients with CRM between 0 and 30 mm [95% confidence interval (CI) = 0.76–0.84], and larger than 30 mm (95% CI = 0.62–0.71), respectively. …”

Table_2_The Circumferential Resection Margin Is a Prognostic Predictor in Colon Cancer.docx by Xin-Yi Tang (9031154)

“…X-tile software identified 0 and 30 mm as optimal cutoff values (P < 0.001) for prognosis, which was applicable only in stage II–IV patients. A 20 and 33% risk decrease were observed in patients with CRM between 0 and 30 mm [95% confidence interval (CI) = 0.76–0.84], and larger than 30 mm (95% CI = 0.62–0.71), respectively. …”

Image 5_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”

BPA is a blocker of human heart sodium channels (hNav1.5). by Andrias O. O’Reilly (148537)

“…<p>A: Dose response curve of tonic block of hNav1.5 by BPA is shown as the relative decrease of sodium current response to a square voltage step to −10 mV (see inset) at various concentrations of BPA from a V_hold of −120 mV (green circles) or −90 mV (blue circles). …”

A model predicting the effects of phosphorylating different sites on the PDFR CT on downstream signaling. by Weihua Li (144468)

“…Primarily, such phosphorylation will decrease the duration of PDFR signaling (red bars) and so reduce (for example) the delay that PDF imposes on the period of neuronal activation displayed by PDFR-responsive pacemaker groups (like the Evening cells and the DN3 [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010013#pgen.1010013.ref010" target="_blank">10</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010013#pgen.1010013.ref019" target="_blank">19</a>]). …”

Image_4_The Circumferential Resection Margin Is a Prognostic Predictor in Colon Cancer.TIFF by Xin-Yi Tang (9031154)

“…X-tile software identified 0 and 30 mm as optimal cutoff values (P < 0.001) for prognosis, which was applicable only in stage II–IV patients. A 20 and 33% risk decrease were observed in patients with CRM between 0 and 30 mm [95% confidence interval (CI) = 0.76–0.84], and larger than 30 mm (95% CI = 0.62–0.71), respectively. …”

Usability of rectal swabs for microbiome sampling in a cohort study of hematological and oncological patients by Lena M. Biehl (6589517)

“…Follow-up samples and those taken under current antibiotic exposure showed a significant decrease in alpha diversity as compared to baseline samples. …”

Image 2_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”

The Full Synaptic Filter has the best overall MSE across a range of parameters. by Jannes Jegminat (8856635)

“…<p><b>(A)</b> The MSE of the Full Synaptic Filter (red) is lower than the MSE of a gradient learning rule (grey) for a range of learning rates <i>η</i>. …”

An Essential Nuclear Protein in Trypanosomes Is a Component of mRNA Transcription/Export Pathway by Mariana Serpeloni (218260)

“…It allowed demonstrating that besides being an essential protein, its knockdown causes mRNA accumulation in the nucleus and decrease of translation levels, reinforcing that Trypanosoma-Sub2 (Tryp-Sub2) is a component of mRNA transcription/export pathway in trypanosomes.…”

Table_3_The Circumferential Resection Margin Is a Prognostic Predictor in Colon Cancer.docx by Xin-Yi Tang (9031154)

“…X-tile software identified 0 and 30 mm as optimal cutoff values (P < 0.001) for prognosis, which was applicable only in stage II–IV patients. A 20 and 33% risk decrease were observed in patients with CRM between 0 and 30 mm [95% confidence interval (CI) = 0.76–0.84], and larger than 30 mm (95% CI = 0.62–0.71), respectively. …”

Maternal complications in pregnancy and childbirth for women with epilepsy: Time trends in a nationwide cohort by Kim Christian Danielsson (8038781)

“…In WWE, folic acid supplementation increased significantly over time (p<0.005), and there was a decrease in smoking during pregnancy (p<0.005), but these changes were less pronounced than for women without epilepsy (p<0.005).…”

Table 1_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.docx by Zhiyi Wang (328693)

“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”

Electric stimulation-guided epidural analgesia for vaginal delivery: A randomized prospective study by Chung Hun Lee (6199430)

“…Successful epidural analgesia was defined as a decrease of 2 or more in the pain score and a bilateral L1-T10 sensory blockade.…”

Image_3_The Circumferential Resection Margin Is a Prognostic Predictor in Colon Cancer.TIFF by Xin-Yi Tang (9031154)

“…X-tile software identified 0 and 30 mm as optimal cutoff values (P < 0.001) for prognosis, which was applicable only in stage II–IV patients. A 20 and 33% risk decrease were observed in patients with CRM between 0 and 30 mm [95% confidence interval (CI) = 0.76–0.84], and larger than 30 mm (95% CI = 0.62–0.71), respectively. …”

Image 3_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”

Table_1_The Circumferential Resection Margin Is a Prognostic Predictor in Colon Cancer.docx by Xin-Yi Tang (9031154)

“…X-tile software identified 0 and 30 mm as optimal cutoff values (P < 0.001) for prognosis, which was applicable only in stage II–IV patients. A 20 and 33% risk decrease were observed in patients with CRM between 0 and 30 mm [95% confidence interval (CI) = 0.76–0.84], and larger than 30 mm (95% CI = 0.62–0.71), respectively. …”

Image_2_The Circumferential Resection Margin Is a Prognostic Predictor in Colon Cancer.TIFF by Xin-Yi Tang (9031154)

“…X-tile software identified 0 and 30 mm as optimal cutoff values (P < 0.001) for prognosis, which was applicable only in stage II–IV patients. A 20 and 33% risk decrease were observed in patients with CRM between 0 and 30 mm [95% confidence interval (CI) = 0.76–0.84], and larger than 30 mm (95% CI = 0.62–0.71), respectively. …”