A small proportion of Talin molecules transmit forces at developing muscle attachments in vivo by Sandra B. Lemke (6519788)

“…Reducing Talin levels at late stages of muscle development results in muscle–tendon rupture in the adult fly, likely as a result of active muscle contractions. We therefore propose that a large pool of adhesion molecules is required to share high tissue forces. …”

Image_1_The Circumferential Resection Margin Is a Prognostic Predictor in Colon Cancer.TIFF by Xin-Yi Tang (9031154)

“…X-tile software identified 0 and 30 mm as optimal cutoff values (P < 0.001) for prognosis, which was applicable only in stage II–IV patients. A 20 and 33% risk decrease were observed in patients with CRM between 0 and 30 mm [95% confidence interval (CI) = 0.76–0.84], and larger than 30 mm (95% CI = 0.62–0.71), respectively. …”

Image 4_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”

CFTR Is a Negative Regulator of NFκB Mediated Innate Immune Response by Neeraj Vij (48990)

“…We verified these results <em>in vivo</em> by comparing survival, body weight and pro-inflammatory cytokine response to <em>P. aeruginosa</em> LPS in CFTR knock out (CFKO) mice as compared to wild type controls. There was a significant (p<0.05) decrease in survival and body weight, an elevation in IL-1β in whole lung extract (p<0.01), as well as a significant increase in phosphorylated IκB, an inducer of NFκB mediated signaling in the CFKO mice.…”

Image 1_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”

Temperature-Induced Phase Transitions of Vivianite: In Situ Analysis of a Redox-Driven Crystallization by Alice Paskin (10017280)

“…Rietveld refinements of the two crystalline endmembers (vivianite and graftonite) revealed a unit cell volume decrease of ∼3.1% during the transformation, which was observed by in situ electron microscopic observations as an overall shrinking of the initial vivianite crystals. …”

Diabetes, Drug Treatment and Mortality in COVID-19: A Multinational Retrospective Cohort Study by Jennifer E. Nyland (11412878)

“…Use of DPP-4 inhibitors was associated with a reduction in respiratory complications (24.0% vs 29.2%; RR, 0.82 [95% CI, 0.74-0.90]; <i>P</i> <.001), and continued use of DPP-4 inhibitors after hospitalization was associated with a decrease in mortality compared with those who discontinued use (9% vs 19%; RR, 0.45 [95% CI, 0.28-0.72]; <i>P</i> <.001). …”

DNA double strand break repair is disrupted in aged <i>fog-2</i> feminized germlines. by Erik Toraason (5724689)

Effects of E2 administration on hemodynamic parameters in OVX rats. by Zahra Hajializadeh (15353940)

Image_1_A Pro-Inflammatory Gut Microbiome Characterizes SARS-CoV-2 Infected Patients and a Reduction in the Connectivity of an Anti-Inflammatory Bacterial Network Associates With S... by Johanna Reinold (11716253)

“…The gut microbiome in SARS-CoV-2 infected patients was characterized by a lower bacterial richness and distinct differences in the gut microbiome composition, including an enrichment of the phyla Proteobacteria and Bacteroidetes and a decrease of Actinobacteria compared to SARS-CoV-2 negative patients. …”

<i>CSF1</i> Is a Novel p53 Target Gene Whose Protein Product Functions in a Feed-Forward Manner to Suppress Apoptosis and Enhance p53-Mediated Growth Arrest by Gregory Azzam (453222)

“…Moreover, we show that increased CSF1/CSF1R signaling in P72 cells feeds back on the p53 pathway to enhance p53 phosphorylation, levels, and transactivation of target genes, particularly the cyclin-dependent kinase inhibitor p21 (<i>CDKN1A</i>). This leads to an increase in p53-mediated growth arrest, along with a concomitant decrease in apoptosis. …”

Image_3_A Pro-Inflammatory Gut Microbiome Characterizes SARS-CoV-2 Infected Patients and a Reduction in the Connectivity of an Anti-Inflammatory Bacterial Network Associates With S... by Johanna Reinold (11716253)

“…The gut microbiome in SARS-CoV-2 infected patients was characterized by a lower bacterial richness and distinct differences in the gut microbiome composition, including an enrichment of the phyla Proteobacteria and Bacteroidetes and a decrease of Actinobacteria compared to SARS-CoV-2 negative patients. …”

Image_2_A Pro-Inflammatory Gut Microbiome Characterizes SARS-CoV-2 Infected Patients and a Reduction in the Connectivity of an Anti-Inflammatory Bacterial Network Associates With S... by Johanna Reinold (11716253)

“…The gut microbiome in SARS-CoV-2 infected patients was characterized by a lower bacterial richness and distinct differences in the gut microbiome composition, including an enrichment of the phyla Proteobacteria and Bacteroidetes and a decrease of Actinobacteria compared to SARS-CoV-2 negative patients. …”

Determinants of Performance of Health Systems Concerning Maternal and Child Health: A Global Approach by Carlos Eduardo Pinzón-Flórez (714364)

“…In order to research on the strength of the association between the annual maternal and child mortality in 154 countries and social determinants: corruption, democratization, income inequality and cultural fragmentation, we used a mixed linear regression model for repeated measures with random intercepts and a conglomerate-based geographical analysis, between 2000 and 2010.…”

Particulate metal exposures induce plasma metabolome changes in a commuter panel study by Chandresh Nanji Ladva (5770811)

“…Features associated with environmental exposures or biological endpoints were identified with a linear mixed effects model and annotated through human metabolic pathway analysis in mummichog.…”

Table_1_Feasibility pilot study of a Japanese teaching kitchen program.docx by Megu Y. Baden (9712437)

“…Background<p>This pilot study examined the feasibility of a new lifestyle modification program involving a “Teaching Kitchen” in Japan. …”

Antibiotic use on German pig farms - A longitudinal analysis for 2011, 2013 and 2014 by Malin Hemme (5478719)

“…The study yielded significant time changes with p-values below 0.001 in antibiotic administration with a decreasing median TF in piglets from 3.8 in the first half of 2011 (IQR = 1.1–10.6) to 1.7 in the second half of 2014 (IQR = 0.2–4.5) and in fattening pigs from 5.1 in the first half of 2011 (IQR = 0.2–15.4) to 0.7 in the second half of 2014 (IQR = 0.1–6.7). …”

Table_1_Feasibility pilot study of a Japanese teaching kitchen program.docx by Megu Y. Baden (9712437)

“…Background<p>This pilot study examined the feasibility of a new lifestyle modification program involving a “Teaching Kitchen” in Japan. …”

Table_1_Feasibility pilot study of a Japanese teaching kitchen program.docx by Megu Y. Baden (9712437)

“…Background<p>This pilot study examined the feasibility of a new lifestyle modification program involving a “Teaching Kitchen” in Japan. …”

UEV-2 is required for ‘youthful’ DNA repair. by Erik Toraason (5724689)