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47861
A Modular Multilevel Voltage-Boosting Marx Pulse-Waveform Generator for Electroporation Applications
Published 2019“…At start up, all the arm's SM capacitors are resonantly charged in parallel from 0 V, simultaneously via directing diodes, to a voltage in excess of the source voltage. After the first pulse delivery, the energy of the SM capacitors decreases due to the generated pulse. …”
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47862
Image3_Artemis inhibition as a therapeutic strategy for acute lymphoblastic leukemia.jpeg
Published 2023“…<p>As effective therapies for relapse and refractory B-cell acute lymphoblastic leukemia (B-ALL) remain problematic, novel therapeutic strategies are needed. Artemis is a key endonuclease in V(D)J recombination and nonhomologous end joining (NHEJ) of DNA double-strand break (DSB) repair. …”
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47863
Metabolic Fingerprints of Altered Brain Growth, Osmoregulation and Neurotransmission in a Rett Syndrome Model
Published 2007“…This approach provided a “metabolic window” to brain characteristics in <em>Mecp2</em>-null mice (n = 4), revealing (i) the first metabolic evidence of astrocyte involvement in RS (decreased levels of the astrocyte marker, <em>myo</em>-inositol, vs. wild-type mice; p = 0.034); (ii) reduced choline phospholipid turnover in <em>Mecp2</em>-null vs. wild-type mice, implying a diminished potential of cells to grow, paralleled by globally reduced brain size and perturbed osmoregulation; (iii) alterations of the platelet activating factor (PAF) cycle in <em>Mecp2</em>-null mouse brains, where PAF is a bioactive lipid acting on neuronal growth, glutamate exocytosis and other processes; and (iv) changes in glutamine/glutamate ratios (p = 0.034) in <em>Mecp2</em>-null mouse brains potentially indicating altered neurotransmitter recycling.…”
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47864
Image_1_A Bibliometric Analysis of Atrophic Gastritis From 2011 to 2021.PNG
Published 2022“…Background<p>Atrophic gastritis (AG), which is characterized by a decreased number or disappearance of the glandular structures and secretory dysfunction, is linked to chronically inflamed stomach. …”
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47865
Image_4_Efficacy of an environmental enrichment intervention for endometriosis: a pilot study.pdf
Published 2023“…Introduction<p>We have previously shown that Environmental Enrichment (EE), a multi-modal psychosocial intervention consisting of increased social interaction, novelty, and open spaces, improved disease presentation, anxiety, and immune-related disturbances in the rat model of endometriosis. …”
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47866
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47867
Table_1_Relationship Between the Pyroptosis Pathway and Epilepsy: A Bioinformatic Analysis.xlsx
Published 2022“…</p>Methods<p>Weighted gene co-expression network analysis (WGCNA) was used to construct a signed co-expression network from expression data to screen gene sets closely related to epilepsy. …”
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47868
Ylide-Substituted Phosphines with a Cyclic Ylide-Backbone: Angle Dependence of the Donor Strength
Published 2021“…Density functional theory calculations revealed that the small angle results in an increased s-character of the lone pair at the ylidic carbon atom and leads to a polarization of the C–P bond toward the carbon atom, thus decreasing the electron density at the phosphorus atom. …”
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47869
DataSheet1_Mathematical Modeling of a Supramolecular Assembly for Pyrophosphate Sensing.PDF
Published 2021“…<p>The power of sensing molecules is often characterized in part by determining their thermodynamic/dynamic properties, in particular the binding constant of a guest to a host. In many studies, traditional nonlinear regression analysis has been used to determine the binding constants, which cannot be applied to complex systems and limits the reliability of such calculations. …”
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47870
Table_4_Relationship Between the Pyroptosis Pathway and Epilepsy: A Bioinformatic Analysis.docx
Published 2022“…</p>Methods<p>Weighted gene co-expression network analysis (WGCNA) was used to construct a signed co-expression network from expression data to screen gene sets closely related to epilepsy. …”
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47871
Image1_Artemis inhibition as a therapeutic strategy for acute lymphoblastic leukemia.jpg
Published 2023“…<p>As effective therapies for relapse and refractory B-cell acute lymphoblastic leukemia (B-ALL) remain problematic, novel therapeutic strategies are needed. Artemis is a key endonuclease in V(D)J recombination and nonhomologous end joining (NHEJ) of DNA double-strand break (DSB) repair. …”
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47872
Image_1_Efficacy of an environmental enrichment intervention for endometriosis: a pilot study.pdf
Published 2023“…Introduction<p>We have previously shown that Environmental Enrichment (EE), a multi-modal psychosocial intervention consisting of increased social interaction, novelty, and open spaces, improved disease presentation, anxiety, and immune-related disturbances in the rat model of endometriosis. …”
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47873
Figures for "Sonic Hedgehog Acts as a Macrophage Chemoattractant During Regeneration of the Gastric Epithelium"
Published 2021“…The recruitment of macrophages plays a central role in the regenerative process. The mechanism that regulates macrophage recruitment in response to gastric injury is largely unknown. …”
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47874
HBV Infection in Relation to Consistent Condom Use: A Population-Based Study in Peru
Published 2011“…Consistent condom use was associated with decreased risk of anti-HBc. Findings from this study emphasize the need of primary prevention programs (vaccination) especially in the jungle population, and imply that condom use promotion might be a potential strategy to prevent HBV infection.…”
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47875
Granulocyte Colony-Stimulating Factor Reduces Fibrosis in a Mouse Model of Chronic Pancreatitis
Published 2014“…<div><p>Background</p><p>Chronic pancreatitis (CP) is a necroinflammatory process resulting in extensive pancreatic fibrosis. …”
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47876
Interaction between two anaesthesia effects leads to a compensatory mechanism in the outcome of the model.
Published 2023“…<p>(<b>A</b>) Difference between context effect, c.e. …”
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47877
Image2_Artemis inhibition as a therapeutic strategy for acute lymphoblastic leukemia.jpeg
Published 2023“…<p>As effective therapies for relapse and refractory B-cell acute lymphoblastic leukemia (B-ALL) remain problematic, novel therapeutic strategies are needed. Artemis is a key endonuclease in V(D)J recombination and nonhomologous end joining (NHEJ) of DNA double-strand break (DSB) repair. …”
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47878
Filament turnover allows active networks to exert sustained stress on a fixed boundary.
Published 2017“…<p><b>A)</b> Snapshots from simulations of active networks with fixed boundaries and different rates of filament turnover. …”
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47879
PfMFR3: A Multidrug-Resistant Modulator in <i>Plasmodium falciparum</i>
Published 2021“…Disruption of <i>pfmfr3</i> and testing against a panel of antimalarial compounds showed decreased sensitivity to MMV085203 and GNF-Pf-3600 as well as other compounds that have a mitochondrial mechanism of action. …”
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47880
Image_3_Efficacy of an environmental enrichment intervention for endometriosis: a pilot study.tiff
Published 2023“…Introduction<p>We have previously shown that Environmental Enrichment (EE), a multi-modal psychosocial intervention consisting of increased social interaction, novelty, and open spaces, improved disease presentation, anxiety, and immune-related disturbances in the rat model of endometriosis. …”