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48681
Table1_Thyroid dysfunction and sarcopenia: a two-sample Mendelian randomization study.docx
Published 2024“…</p>Results<p>The MR analysis indicated that hyperthyroidism could lead to a significant decrease in ALM in the extremities (OR = 1.03; 95% CI = 1.02 to 1.05; P < 0.001). …”
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48682
DataSheet1_A Zebrafish Model of Neurotoxicity by Binge-Like Methamphetamine Exposure.PDF
Published 2021“…After an initial testing at 20 and 40 mg/L for 48 h, the later METH concentration was selected for developing the model and the effects on the brain monoaminergic profile, locomotor, anxiety-like and social behaviors as well as on the expression of key genes of the catecholaminergic system were determined. A concentration- and time-dependent decrease in the brain levels of dopamine (DA), norepinephrine (NE) and serotonin (5-HT) was found in METH-exposed fish. …”
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48683
Comprehensive Analysis of the Naturally Processed Peptide Repertoire: Differences between HLA-A and B in the Immunopeptidome
Published 2015“…After viral infection, the number of unique self-peptides eluted significantly decreased compared to uninfected cells, paralleled by a decrease in the number of source proteins. …”
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48684
Table_1_A Pilot Study on Serial Nerve Ultrasound in Miller Fisher Syndrome.DOCX
Published 2020“…<p>Objective: Miller Fisher syndrome (MFS) is predominantly a clinical diagnosis, with classic triad of ophthalmoplegia, ataxia, and generalized reduced reflexes. …”
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48685
Doses of enzyme complex in a high-energy diet on performance and carcass traits of feedlot steers
Published 2018“…Each gram of product added to the diet led to a decrease of 0.0818 kg in daily dry matter intake (DMI), whereas fat thickness at the ribs and at the hindquarter increased by 0.3850 and 0.080 mm, respectively. …”
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48686
Image_1_Transmembrane Peptides as a New Strategy to Inhibit Neuraminidase-1 Activation.jpg
Published 2020“…Accumulative data have shown that inhibition of neuraminidases, such as NEU1 sialidase, may be a promising pharmacological target, and selective inhibitors of NEU1 are therefore needed to better understand the biological functions of this sialidase. …”
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48687
Synthesis and Preclinical Validation of Novel Indole Derivatives as a GPR17 Agonist for Glioblastoma Treatment
Published 2021“…The <b>CHBC</b>–GPR17 interaction leads to a rapid decrease of cAMP and Ca<sup>2+</sup>. <b>CHBC</b> exhibits the cytotoxicity effect on GBM cells in a dose-dependent manner with an IC<sub>50</sub> of 85 μM, whereas the known agonist MDL29,951 showed a negligible effect. …”
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48688
Nitrogen addition increases aboveground silicon and phytolith concentrations in understory plants of a tropical forest
Published 2021“…The significant accumulation of Si in the leaves and the unaltered plant-available Si concentrations in the soil were associated with enhanced plant Si uptake and decreased soil phytolith return due to increased phosphorus <a>(P) limitation</a>, soil acidification, and decreased leaf C:N ratios caused by N addition.…”
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48689
Social and Demographic Effects of Anthropogenic Mortality: A Test of the Compensatory Mortality Hypothesis in the Red Wolf
Published 2011“…When involving the death of a breeder, anthropogenic mortality was also additive to natural rates of breeding pair dissolution, resulting in a net decrease in the annual preservation of existing breeding pairs. …”
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48690
<i>Chk1</i>+/− mice show a disruption in enucleation of erythrocytes in the bone marrow.
Published 2010“…The P2 gated cells, the majority of which should be immature erythrocytes with their nuclei still intact show a decrease in nucleated cells with a concurrent increase in enucleated cells in the <i>Chk1+/−</i> whole bone marrow. …”
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48691
Increased Immunogenicity and Protective Efficacy of Influenza M2e Fused to a Tetramerizing Protein
Published 2012“…Most importantly, vaccination with M2e-NSP4 caused a significant decrease in lung virus load early after challenge with influenza A virus and maintained its efficacy against a lethal challenge even at very low vaccine doses. …”
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48692
BioMAP biomarker profiles for (A) ruxolotinib, (B) fedratinib, (C) momelotinib, and (D) pacritinib.
Published 2019“…Biomarker key activities are described as modulated if these activities increase in some systems, but decrease in others. Cytotoxicity is indicated on the profile plot by a thin black arrow above the X-axis, and antiproliferative effects are indicated by a thick grey arrow. …”
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48693
A comprehensive meta-analysis on evidence of Mediterranean diet and cardiovascular disease: Are individual components equal?
Published 2017“…We performed a meta-analysis to explore the association in prospective studies and randomized control trials (RCTs) between Mediterranean diet adherence and CVD incidence and mortality. …”
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48694
A Tale of Two Morphs: Modeling Pollen Transfer, Magic Traits, and Reproductive Isolation in Parapatry
Published 2014“…In a different pollination scenario, however, precise pollen transfer causes a decrease in adaptive divergence by promoting asymmetric gene flow. …”
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48695
Identification of <i>Abhd2</i> as a driver of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) in liver.
Published 2023“…<p>(<b>A</b>) LOD profiles for <i>Abhd2</i> expression and abundance of several phospholipids in liver identify a common quantitative trait locus (QTL) at ~79 Mbp on chromosome 7. …”
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48696
Modulation of TLX and PNR transcriptional activities by ccrp1, ccrp2 and ccrp3. A.
Published 2014“…<p>Transfections of TLX LBD repress the UAS promoter leading to a decrease in luciferase activities compared to the control (cells transfected with empty GAL4 vector). …”
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48697
Poincaré maps for the best no-FIC (A1) and post-FIC (B1) MMF fit.
Published 2024“…A decrease in number of nodes in a single regime or an increase in the number of nodes in two or three regimes is considered a richer repertoire of behaviors as a result of implementing dFIC.…”
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48698
Clinical efficacy and safety of mesenchymal stem cell transplantation for osteoarthritis treatment: A meta-analysis
Published 2017“…We demonstrated that MSC treatment could significantly decrease VAS and increase IKDC scoresafter a 24-month follow-up compared with controls (<i>P</i><0.05). …”
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48699
Machine Learning for Two-Phase Flow Separation in a Liquid–Liquid Interface Manipulation Separator
Published 2023“…Two-phase flow separation is a key step in various downstream purification processes. …”
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48700
Incidence of lower extremity amputations in the diabetic compared with the non-diabetic population: A systematic review
Published 2017“…Study designs, statistical methods, definitions of major and minor amputations, as well as the methods to identify patients with diabetes differed greatly, explaining in part these considerable differences. Some studies found a decrease in incidence of LEA as well as relative risks over time. …”