Image_2_Transmembrane Peptides as a New Strategy to Inhibit Neuraminidase-1 Activation.jpg by Camille Albrecht (9774560)

“…Accumulative data have shown that inhibition of neuraminidases, such as NEU1 sialidase, may be a promising pharmacological target, and selective inhibitors of NEU1 are therefore needed to better understand the biological functions of this sialidase. …”

Supplemental materials for Effects of age on human skeletal muscle: A systematic review and meta-analysis by Christopher Lee (19739632)

“…<p dir="ltr">Human studies examining the cellular mechanisms behind sarcopenia, or age-related loss of skeletal muscle mass and function, have produced inconsistent results. A systematic review and meta-analysis were performed to determine the aging effects on protein expression, size and distribution of fibers with various myosin heavy chain (MyHC) isoforms. …”

Table_1_EMDR in pediatric hospital setting: a case report of an adolescent with cancer.pdf by Sabrina Ciappina (18237379)

“…</p>Results<p>By using EMDR protocol the patient reported a decrease of emotional activation after a few EMDR sessions.…”

Potent Sensitisation of Cancer Cells to Anticancer Drugs by a Quadruple Mutant of the Human Deoxycytidine Kinase by Safiatou T. Coulibaly (816058)

“…Importantly, a remarkable effect is also observed in treatments with the anticancer compound cytarabine (AraC), for which a 10,000 fold decrease in IC50 occurred. …”

Glycine promotes longevity in <i>Caenorhabditis elegans</i> in a methionine cycle-dependent fashion by Yasmine J. Liu (6433946)

“…In this study we show that this is coupled to a decrease in gene expression of enzymes important for glycine catabolism. …”

Effect of GluA2 RNAi on the dendritic morphology of E11 chicken lumbar motoneurons. by Yone J. Yoon (296191)

“…<p><i>A</i><b><i>–D</i></b><i>)</i> Infection of chicken embryos with the RCASBP(B)-RFP-GluA2 RNAi construct causes a significant decrease in the dendritic complexity of E11 motoneurons. …”

Assessment of Peripheral Airway Function following Chronic Allergen Challenge in a Sheep Model of Asthma by Joanne Van der Velden (192424)

“…Furthermore, while there was a decline in peripheral airway function with HDM exposure, this decrease was not correlated with the length of allergen challenge.…”

Distribution of the Mixture Model Posterior Probability of Infection Among Participants with a Rise in IgG. by Jo Walker (22404069)

“…Participants who experienced a decrease in IgG between visits were assumed to have not been infected and are not included in this figure. …”

Effect of a rosmarinic acid supplemented hemodialysis fluid on inflammation of human vascular endothelial cells by W-J. Wang (6513719)

“…Inhibition of proinflammatory mediator production in HUVECs by RA supplementation to HDF was significant in a dose-dependent manner. Exposure to RA-supplemented HDF resulted in a decrease in nitric oxide synthase expression and reduction of NO production in LPS-stimulated HUVECs. …”

Relative effort (+ standard deviation), estimated, when optimising for A) profit and B) ecological stability. by Johanna Jacomina Heymans (219773)

“…When optimising for ecological stability (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0020239#pone-0020239-g003" target="_blank">Figure 3B</a>) the relative effort will have to decrease significantly from that of 2003, and that effort with subsidies will be marginally higher than without.…”

A Mutation in the Mouse <i>Ttc26</i> Gene Leads to Impaired Hedgehog Signaling by Ruth E. Swiderski (650087)

“…Although IFT is required for ciliogenesis, the Ttc26 defect did not result in a decrease in the number or length of primary cilia. …”

Video_1_Functional Mobility Training With a Powered Knee and Ankle Prosthesis.MP4 by Suzanne B. Finucane (12394894)

“…<p>Limb loss at the transfemoral or knee disarticulation level results in a significant decrease in mobility. Powered lower limb prostheses have the potential to provide increased functional mobility and return individuals to activities of daily living that are limited due to their amputation. …”

Video_1_Functional Mobility Training With a Powered Knee and Ankle Prosthesis.MP4 by Suzanne B. Finucane (12394894)

“…<p>Limb loss at the transfemoral or knee disarticulation level results in a significant decrease in mobility. Powered lower limb prostheses have the potential to provide increased functional mobility and return individuals to activities of daily living that are limited due to their amputation. …”

Numerical investigation on the impact of natural convection on a multi-inlet industrial rooftop photovoltaic system by Xiaomeng Wang (348745)

“…Especially on the roofs of large industrial plants, it is necessary to install as many photovoltaic panels as possible while avoiding a significant increase in panel temperature that could lead to a decrease in efficiency. …”

Genetic variants in mitochondrial sirtuins associated with brain tumor risk: a case–control study by Maria Fazal Ul Haq (14659737)

“…Haplotype analysis and linkage disequilibrium (LD) showed a strong LD in brain tumor patients. Kaplan–Meier analysis showed that mutant allele frequency was found to be associated with a significant decrease in the survival of brain tumor patients.…”

eNOS-Dependent Antisenscence Effect of a Calcium Channel Blocker in Human Endothelial Cells by Toshio Hayashi (521209)

“…Exposure of HUVECs to high glucose (22 mM) for 3 days increased senescence-associated- β-galactosidase (SA-β-gal) activity, a senescence marker, and decreased telomerase activity, a replicative senescence marker. …”

<i>FOXO1</i> is a direct target of miR-582-5p. by Yanhua Liu (164798)

“…(C) Co-transfection of miR-582-5p mimics/mimics NC and <i>FOXO1</i> 3′UTR-luciferase reporter vector into HEK-293T cells demonstrated that significant decrease in luciferase activity was only found in reporter vector that contained a wild type sequence (FOXO1-3′UTR-wt), not in vector that contained a mutant sequence (FOXO1-3′UTR-mut) within the miR-582-5p binding site. …”

p53 acts as a gatekeeper by preventing progression of oncogenically activated cells to full malignancy. by George Hinkal (371132)

“…When p53 is deleted by tamoxifen injection at 3, 6, or 12 months or following IR treatment in CreERT2-p53^F/F mice, some oncogenic clones will progress to form a malignant cancer. For the p53^F/F mice, the median and maximal tumor latencies following p53 deletion decrease with age or with carcinogenic insult. …”

Supplementary Material for: Effects of exercise during chemo- or radiotherapy on immune markers – a systematic review by DeHoop A.M.S. (17085538)

“…The majority of markers was unaltered, but observed effects included a suppressive effect of exercise during radiotherapy on some pro-inflammatory markers, a preserving effect of exercise during chemotherapy on NK cell degranulation and cytotoxicity, a protective effect on the decrease in thrombocytes during chemotherapy, and a positive effect of exercise during chemotherapy on IgA. …”

The Potential Connectivity of Waterhole Networks and the Effectiveness of a Protected Area under Various Drought Scenarios by Georgina O’Farrill (564895)

“…The Greater Calakmul Region of the Yucatan Peninsula (Mexico) has experienced a 16% decrease in precipitation over the last 50 years, which we hypothesise has affected water resource connectivity. …”