SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle by Koltai, Erika

“…We report here that the levels of miR1 and miR133a decrease in hypertrophy and negatively correlate with muscle mass, SIRT1 and Nampt levels. …”
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Inequalities in Alcohol-Related Mortality in 17 European Countries: A Retrospective Analysis of Mortality Registers by Johan P. Mackenbach (147412)

“…<div><p>Background</p><p>Socioeconomic inequalities in alcohol-related mortality have been documented in several European countries, but it is unknown whether the magnitude of these inequalities differs between countries and whether these inequalities increase or decrease over time.</p><p>Methods and Findings</p><p>We collected and harmonized data on mortality from four alcohol-related causes (alcoholic psychosis, dependence, and abuse; alcoholic cardiomyopathy; alcoholic liver cirrhosis; and accidental poisoning by alcohol) by age, sex, education level, and occupational class in 20 European populations from 17 different countries, both for a recent period and for previous points in time, using data from mortality registers. …”

The proppin Bcas3 and its interactor KinkyA localize to the early phagophore and regulate autophagy by Yoko Yamada (335696)

“…<i>knkA⁻</i> and <i>bcas3⁻</i> cells showed a pronounced decrease of RFP-GFP-Atg8 in neutral early autophagosomes, indicating that KnkA and Bcas3 are required for macroautophagy/autophagy. …”

Table_1_Music Listening in Times of COVID-19 Outbreak: A Brazilian Study.pdf by Fabiana Silva Ribeiro (6427277)

“…<p>The COVID-19 outbreak required diverse strategies, such as social distancing and self-isolation, to avoid a healthcare system crisis. However, these measures have been associated with the onset or increase of anxiety and depression symptoms in the population. …”

Persistent differences between coastal and offshore kelp forest communities in a warming Gulf of Maine by Jon D. Witman (2913377)

“…<i>latissima</i> underwent a significant 36.2% decrease between 1987 and 2015 on Cashes Ledge, concurrent with a rapid warming of the GOM and invasion by the kelp-encrusting bryozoan <i>Membranipora membranacea</i>. …”

Loss of CypD protects axonal mitochondrial motility and dynamics from Aβ toxicity. by Lan Guo (278497)

“…(<b>B</b>) CypD depletion decreased the percentage of stationary mitochondria in Aβ-treated neurons. …”

A first estimate of the structure and density of the populations of pet cats and dogs across Great Britain by James Aegerter (3921485)

“…In addition, the lack of spare capacity to care for unowned cats in welfare organisations suggests that any increase in their rate of acquisition of cats, or any decrease in the rate of re-homing might provoke problems during a period of crisis.…”

Oxidative and Anti-Oxidative Stress Markers in Chronic Glaucoma: A Systematic Review and Meta-Analysis by Cédric Benoist d’Azy (2817379)

“…We demonstrated an overall increase in oxidative stress markers in glaucoma (effect size = 1.64; 95%CI 1.20–2.09), ranging from an effect size of 1.29 in serum (95%CI 0.84–1.74) to 2.62 in aqueous humor (95%CI 1.60–3.65). Despite a decrease in antioxidative stress marker in serum (effect size = –0.41; 95%CI –0.72 to –0.11), some increased in aqueous humor (superoxide dismutase, effect size = 3.53; 95%CI 1.20–5.85 and glutathione peroxidase, effect size = 6.60; 95%CI 3.88–9.31). …”

Inflammation and Gli2 Suppress Gastrin Gene Expression in a Murine Model of Antral Hyperplasia by Milena Saqui-Salces (126581)

“…Moreover, chromatin immunoprecipitation of GLI2 in AGS cells confirmed that GLI2 directly binds to the <em>GAST</em> promoter. Using a mouse model of constitutively active epithelial GLI2 expression, we found that activated GLI2 repressed <em>Gast</em> expression but induced <em>Il-1β</em> gene expression and proliferation in the gastric antrum, along with a reduction of the number of G-cells. …”

Data_Sheet_1_Variation of ewe olfactory secretome during a ram effect.PDF by Paul Cann (7593149)

“…In natural conditions, the transition between sexual rest and sexual activity in both sexes is induced by the decrease of day light. Meanwhile, specific odors emitted by a sexually active male are able to reactivate the gonadotropic axis of anovulatory ewes. …”

How significant a role can China’s forest sector play in decarbonizing its economy? by Jianyun Hou (13018981)

“…It is also crucial to put these actions into a coherent framework of C accounting. Building on these steps, we show that during 2006–2020, the sector’s biomass and soil C sequestration reached 2.589 petagrams (Pg) and 1.275 Pg respectively, and its C storage in HWPs added 0.491 Pg. …”

Effects of Bio-Inspired Surface Roughness on a Swept Back Tapered NACA 4412 Wing by Khurshid Malik (6546170)

“…Surface roughness delays the stall angle and decreases the lift. The wing with the roughness elements located at 75% to 95% of mean chord from leading edge shows minimum drag and maximum lift compared to other locations. …”

TNNI3K expression leads to systolic dysfunction in a surgically induced model of cardiomyopathy. by Ferrin C. Wheeler (259443)

“…Data is represented by mean±SEM.</p>…”

THE ROLE OF QATAR COMMUNITY PHARMACISTS IN DEPRESSION CARE: A SURVEY OF ATTITUDES, PRACTICES AND PERCEIVED BARRIERS by SHAMI, RULA

“…Out of a possible score of 5, the mean score of attitudes was 3.41, with a standard deviation of 0.94. …”
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Cardiovascular autonomic modulation and baroreflex control in the second trimester of pregnancy: A cross sectional study by Mikaela da Silva Corrêa (6697157)

“…During STAND, CG and PG decreased the mean, CI, NCI and 2UV% and increased 0V% of the HP series and augmented the SAP variance. …”

Phase 1 Study of a Sulforaphane-Containing Broccoli Sprout Homogenate for Sickle Cell Disease by Jennifer F. Doss (399190)

“…We also observed a trend toward increased mean relative mRNA levels of the NRF2 target <i>HBG1</i> (p = 0.10) from baseline to end of treatment, but without significant changes in HbF protein. …”

Effects of FGF-2 and/or a soft substratum on TGF-β-induced expression of α-SMA. by Tomoyo Matsumura (9656681)

“…The induction of α-SMA by TGF-β2 was decreased on a soft substratum in the softness-dependent manner. …”

Matlab_code_2017WR021645 by Matthias Loschko (4693123)

“…Code for paper: Accounting for the Decreasing Reaction Potential of Heterogeneous Aquifers in a Stochastic Framework of Aquifer-Scale Reactive Transport, Paper # 2017WR021645…”

A. IP₃ receptors lateral mobility in ER patches and reticular ER. by Lu Sun (194355)

“…As IP₃ receptor cluster size increases the delay in response to an IP₃ pulse decreases. <b>C.</b> Modeling Ca²⁺ release spatial and amplitude distribution from two IP₃ receptor clusters of varying size (20 and 1000) in response to a sub-threshold IP₃ pulse. …”

Detailed Diagram of the SAMCell Pipeline, with stages (a) Ground truth distance map creation for training/fine-tuning (b) Fine-tuning of the Segment Anything Model, where we choose... by Alexandra Dunnum VandeLoo (22209218)