Structure–Activity Studies of 1<i>H</i>‑Imidazo[4,5‑<i>c</i>]quinolin-4-amine Derivatives as A₃ Adenosine Receptor Positive Allosteric Modulators by Lucas B. Fallot (14106171)

“…We synthesized new analogues to distinguish 2-cyclopropyl antagonist <b>17</b> (orthosteric interaction demonstrated by binding and predicted computationally) from PAMs (derivatives with large 2-alkyl/cycloalkyl/bicycloalkyl groups). We predicted PAM binding at a hydrophobic site on the A₃AR cytosolic interface. …”

High glucose-containing media reduces the steady-state levels of internalized oAβ in microglia and astrocytes in mixed glia cultures. by Yung-Cheng Huang (3443450)

Electrospun Gold Nanoprism/Poly(vinyl alcohol) Nanofibers for Flexible and Free-Standing Surface-Enhanced Raman Scattering Substrates by Alei Dang (1707214)

“…Using 4-mercaptobenzoic acid (4-MBA) as the target molecule, we show that the nanofiber mat with 20 nM AuNPs exhibits high sensitivity at a concentration as low as 10^–10 M 4-MBA with an enhancement factor of 10⁷ and good uniformity over a very large area (20 cm²) with an average relative standard deviation of <0.074. …”

Smoking impact on fibrosis and cancer gene expression. by Lorise C. Gahring (271630)

“…<p>A. Representative longitudinal sections through the large lobe of the lung of mice as indicated. …”

Changes to distal lung structure of both α7 genotypes with and without CS exposure. by Lorise C. Gahring (271630)

“…In these representative sections the arrows point to AMs and in the α7^E260A:G arrow heads identify regions of increased cellularity that produce alveolar sacs of decreased size. …”

Summary statistics for <i>Varroa</i> intensity in number of mites per 300 bees and potential environmental explanatory variables, Mean (SD). Note that the standard deviation for fl... by Laura Boehm Vock (22008756)

“…Floral quality and insecticide load are more variable in southern IL in particular (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0325801#pone.0325801.g002" target="_blank">Fig 2</a>), decreasing the SD for the testing data.…”

Shifts in Abundance and Diversity of Soil Ammonia-Oxidizing Bacteria and Archaea Associated with Land Restoration in a Semi-Arid Ecosystem by Zhu Chen (3106)

“…The project converted large areas (ca 10 million ha) of steep-sloped/degraded farmland and barren land into forest and grassland resulting in ecological benefits such as a reduction in severe soil erosion. …”

MAPK inhibitors alter CK/CHK production without reducing viral protein production in either cell type. by Georgetta Cannon (623017)

“…<p>As MAPK inhibition did not substantially block FLUA protein production the decreased CK/CHK production is not due to a direct anti-viral effect of the inhibitors. …”

Blocking SLC7A11 attenuates the proliferation of esophageal squamous cell carcinoma cells by Wen-Ting Li (767461)

“…<p>The role of ferroptosis-associated gene SLC7A11 in esophageal cancer progression is largely unknown, therefore, the effects of blocking SLC7A11 on esophageal squamous cell carcinoma (ESCC) cells are evaluated. …”

Hepatic oxylipin profiles in WT and sEH-KO mice. by Ye Zhu (646531)

“…<p>(A), (B): Metabolic deficiency of sEH resulted in decreased DiHOME/EpOME- (A) as well as 14,15-DHET/14,15-EET-ratios (B). …”

Involvement of Rho GAP GRAF1 in maintenance of epithelial phenotype by Miriam Regev (3096801)

“…GRAF1 expression in several highly invasive breast cancer cell lines was low, as compared to the non-malignant MCF10A cells, while overexpressing of GRAF1 in the malignant BT-549 cell line led to a decrease of mesenchymal markers, especially the Snail-1 and 2. …”

Long non-coding RNA PMS2L2 is down-regulated in osteoarthritis and inhibits chondrocyte proliferation by up-regulating miR-34a by Fei Yang (46361)

“…From these findings, one may conclude that finding means to regulate PMS2L2 could be a promising new target in the development of regimens for the treatment of OA.…”

Renal oxylipin profiles in WT and sEH-KO mice. by Ye Zhu (646531)

“…<p>(A): The conversion of linoleic acid-derived epoxides (EpOMEs) to the corresponding vicinal diols (DiHOMEs) was reduced in sEH-KO compared to WT mice as indicated by the decreased DiHOME/EpOME-ratios. …”

Plasma oxylipin profiles in WT and sEH-KO mice. by Ye Zhu (646531)

“…<p>(A): The conversion of linoleic acid-derived epoxides (EpOMEs) to the corresponding vicinal diols (DiHOMEs) was reduced in sEH-KO compared to WT mice as indicated by the decreased DiHOME/EpOME-ratios. …”

HilD induction does not affect flagellation. by Doaa Osama Saleh (16353149)

Supplementary Material for: Change in Proportional Protein Intake in a 10-Week Energy-Restricted Low- or High-Fat Diet, in Relation to Changes in Body Size and Metabolic Factors by Stocks T. (4139956)

“…<b><i>Conclusions:</i></b> Under energy restriction, participants on a low-fat diet who had increased the percentage energy intake from protein showed the greatest reduction in weight and cholesterol, and a triglyceride reduction equally large to that of participants on a high-fat diet.…”

HilD activates expression of adhesive structures in <i>Salmonella</i> Typhimurium. by Doaa Osama Saleh (16353149)

Age-dependent changes in the thermal stability of nuclear lamin-B and CP190. by Wei-Qi Lin (2518108)

HilD induction results in membrane depolarization. by Doaa Osama Saleh (16353149)

Pharmacokinetic analysis of LY5 in mice and normal dogs. by Peter Y. Yu (4281448)