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62801
Computational modeling of the bimodal distribution of RPs and altered parameters of the resting ion channels on the distribution of RPs.
Published 2015“…(<b><i>A</i></b>) The initial parameter inputs included simultaneously the four conductances with randomly generated variations around the means derived from (rounded) whole-cell measurements of single SMA cells. …”
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62802
Immobility results in an increase in the transcriptional status and immunodetection of Atrogin-1 and MuRF-1 in the early phase of disuse muscle atrophy.
Published 2012“…<p><b>A & B</b>. The mRNA level of Atrogin-1 and MuRF-1 was determined using qRT-PCR and significant increases were found in the early phase (2–4 days) of immobility, in both young and old skeletal muscle. …”
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62803
Scoparone suppresses anchorage-independent growth <i>in</i><i>vitro</i> and xenograft tumor growth of DU145 cells in nude mice.
Published 2013“…<p>A. Scoparone inhibits anchorage-independent growth of DU145 cells. …”
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62804
Separating Fusion from Rivalry
Published 2014“…<div><p>Visual fusion is the process in which differing but compatible binocular information is transformed into a unified percept. Even though this is at the basis of binocular vision, the underlying neural processes are, as yet, poorly understood. …”
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62805
Negative regulation of <i>sNPF/NPY</i> by insulin signaling.
Published 2012“…<p>(A, B) Insulin treatment increased FoxO1 phosphorylation and decreased <i>NPY</i> expression in mouse hypothalamic GT1-7 cells while insulin with AKT inhibitor co-treatment slightly decreased FoxO1 phosphorylation and increased <i>NPY</i> expression. …”
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62806
Effects of miR-143 on PTGS2 expression in AECs and AMCs.
Published 2013“…<p>A, qRT-PCR analysis shows that 50 nM of miR-143 mimic transfection significantly increases miR-143 expression, while transfection with 200 nM of miR-143 inhibitor has no effect in AECs. …”
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62807
Uric acid contributes to the survival of termite worker under laboratory conditions.
Published 2017“…<p>(A) Survival rates of termite workers following allopurinol administration for 10 days. …”
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62808
Antioxidant Activity of Fermented Soybean Extract
Published 2004“…The results demonstrate that the fermented soybean extract has strong antioxidant activity against unsaturated fatty acid peroxidation compared to vitamin C and Trolox. By the means of the test system developed by Y. Toshiki et al., it is shown that the fermented soybean extract can function both as an antioxidant and as a free radical acceptor that can convert free radicals into harmless substances through an energy-decreasing procedure. …”
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62809
Techniques, challenges, and opportunities in mobile thematic map design for data journalism
Published 2025“…This work shows that news cartographers solve mobile thematic map design challenges through iterative design processes that draw from years of expertise, not a strict set of guidelines.</p> <p></p><p>News cartographers currently design mobile thematic maps based on generalized best practices, but are uncertain what choices do and do not work for their readers</p><p>Many news cartographers design maps simultaneously for desktop and mobile, rather than prioritizing one over the other</p><p>News cartographers are decreasing their use of interactive maps, given that they expect news readers want to consume information as fast as possible</p><p>News maps are produced under time constraints that can be limiting on creativity and novelty, and without time for user testing</p><p></p> <p>News cartographers currently design mobile thematic maps based on generalized best practices, but are uncertain what choices do and do not work for their readers</p> <p>Many news cartographers design maps simultaneously for desktop and mobile, rather than prioritizing one over the other</p> <p>News cartographers are decreasing their use of interactive maps, given that they expect news readers want to consume information as fast as possible</p> <p>News maps are produced under time constraints that can be limiting on creativity and novelty, and without time for user testing</p>…”
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62810
EV71 infection induces neurodegeneration via activating TLR7 signaling and IL-6 production
Published 2019“…However, the mechanisms underlying the regulation of TLR7-mediated brain pathogenesis upon EV71 infection remain largely elusive. Here we reveal a novel mechanism by which EV71 infects astrocytes in the brain and induces neural pathogenesis <i>via</i> TLR7 and interleukin-6 (IL-6) in C57BL/6 mice and in human astroglioma U251 cells. …”
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62811
Type 2 Diabetes Subgroups, Risk for Complications, and Differential Effects Due to an Intensive Lifestyle Intervention
Published 2021“…ILI focused on weight loss through decreased caloric intake and increased physical activity. …”
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62812
Exploring the barriers and incentive architecture for modifying smoke exposures among asthmatics
Published 2020“…<i>Results</i>: Home smoking restrictions were a frequently referenced strategy for decreasing SHSe, but interviewees (<i>n</i> = 22) described the complex social pressures that undermine reduction efforts. …”
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62813
Properties of acetylcholine-induced [Ca<sup>2+</sup>]i elevation in SH-SY5Y cells.
Published 2020“…Compared with the outcome of acetylcholine treatment alone, the [Ca<sup>2+</sup>]i was steeply elevated but was quickly decreased. In both (A) and (B), a representative of 5 independent trials is shown. …”
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62814
Image_3_The Molecular Mechanism Underlying Pro-apoptotic Role of Hemocytes Specific Transcriptional Factor Lhx9 in Crassostrea hongkongensis.jpg
Published 2018“…RNA interference of ChLhx9 dramatically decreased the apoptosis rate of hemocytes when compared with a control group, which strongly implies its pro-apoptotic role in hemocytes. …”
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62815
Table_1_The Molecular Mechanism Underlying Pro-apoptotic Role of Hemocytes Specific Transcriptional Factor Lhx9 in Crassostrea hongkongensis.DOCX
Published 2018“…RNA interference of ChLhx9 dramatically decreased the apoptosis rate of hemocytes when compared with a control group, which strongly implies its pro-apoptotic role in hemocytes. …”
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62816
<sup>31</sup>P NMR spectroscopy indicates an energy deficit in 6-week-old <i>mdx</i> mice.
Published 2014“…The inorganic phosphate, phosphocreatine, and three phosphate group peaks for ATP are labeled and marked by a tick mark. Graphs are aligned by parallel lines connecting the ATP peaks; phosphocreatine and inorganic phosphate showed differences between wild-type and <i>mdx</i> mice and are highlighted by a red box. …”
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62817
Image_1_The Molecular Mechanism Underlying Pro-apoptotic Role of Hemocytes Specific Transcriptional Factor Lhx9 in Crassostrea hongkongensis.JPEG
Published 2018“…RNA interference of ChLhx9 dramatically decreased the apoptosis rate of hemocytes when compared with a control group, which strongly implies its pro-apoptotic role in hemocytes. …”
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62818
Image_1_PKM2 Interacts With the Cdk1-CyclinB Complex to Facilitate Cell Cycle Progression in Gliomas.tiff
Published 2022“…Moreover, PKM2 knock-down decreased Cdk1 activity while introducing a constitutively active Cdk1 reversed the effects of PKM2 knock-down on cell cycle progression. …”
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62819
Data_Sheet_2_The Molecular Mechanism Underlying Pro-apoptotic Role of Hemocytes Specific Transcriptional Factor Lhx9 in Crassostrea hongkongensis.XLS
Published 2018“…RNA interference of ChLhx9 dramatically decreased the apoptosis rate of hemocytes when compared with a control group, which strongly implies its pro-apoptotic role in hemocytes. …”
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62820
<i>Gli3</i>-deficient mice exhibit increased behavioral responses to sweet, umami, and bitter tastants.
Published 2018“…Compared to <i>Gli3</i><sup><i>WT</i></sup> mice, <i>Gli3</i><sup><i>CKO</i></sup> mice display increased lick responses over a range of concentrations to the appetitive stimuli (sucrose, sucralose, and MSG) and decreased lick responses to the aversive stimuli (denatonium and citric acid). …”