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Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain
Published 2022“…In addition, nicotine individually decreased expression levels of all examined protein targets, significantly for CYP1B1 (p < 0.001), CYP19A1 (p = 0.010), AhRR (p = 0.042), and ARNT (p < 0.001), compared to control. …”
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Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
Published 2017“…Maturity-onset diabetes of the young type 3 (MODY3) is a non-ketotic form of diabetes associated with poor insulin secretion. …”
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Comparative skull analysis suggests species-specific captivity-related malformation in lions (Panthera leo)
Published 2014“…Lion (Panthera leo) populations have dramatically decreased worldwide with a surviving population estimated at 32,000 across the African savannah. …”
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Effect of Bariatric Surgery on Serum Amyloid A Protein: a Systematic Review and Meta-analysis
Published 2023“…Background: Obesity is a chronic inflammatory condition and this meta-analysis evaluated the impact of bariatric surgery on SAA. …”
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Heat-stress-induced changes in enzymatic antioxidant activities and biochemical processes in bell pepper (Capsicum annuum L.) seedlings
Published 2023“…At 40 and 32 °C, HS led to a decrease in chlorophyll a (4.327 mg g–1 FW), b (1.710 mg g–1 FW), total chlorophyll (5.202 mg g–1 FW), and total carotene (1.092 mg g–1 FW) compared to the control at 25 °C (chlorophyll a 5.383 mg g–1 FW, chlorophyll b 2.358 mg g–1 FW, total chlorophyll 6.692 mg g–1 FW, and total carotene 1.817 mg g–1 FW). …”
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Necrotizing Fasciitis caused by Streptococcus pyogenes: A case report and literature review of disease diagnosis and management
Published 2017“…Background: A 55-year-old male presented to the emergency room at a local hospital complaining of chest discomfort and severe left elbow pain. …”
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The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells.
Published 2019“…Pb treatment induced oxidative stress by a) increasing the formation of reactive oxygen species and b) decreasing GSTA1 mRNA levels. …”
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S1.P170 A terpenoids-enriched fraction of Inula viscosa: its chemical composition and anti-cancerous effects against human lung cancer cells
Published 2024“…The anti-cancerous potential of ZNE and F6 was tested in vitro in MDA-MB-231 cells, a TNBC cell line. ZNE and F6 radical scavenging capacity was tested using DPPH assay, and their effects on reactive oxygen species (ROS) generation in vitro in cells by DCFDA staining. …”
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Deregulation of cell growth and apoptosis in UV-induced melanomagenesis
Published 2020“…More interestingly, p16 mutant cells increased their resistance to apoptosis at high UVB-dose, associated with decreased Bax and increased Bcl2 expression. Thus, mutant-p16 appears to dictate a deregulation of cell cycle and increased resistance to apoptosis in melanoma cells. …”
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Improved mechanical properties of recycled linear low-density polyethylene composites filled with date palm wood powder
Published 2014“…Recycled linear low-density polyethylene (RLLDPE) was blended with date palm wood powder to prepare composites in which the concentration of the filler ranged from 10 to 70wt.%. …”
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Hyperhydration-induced decrease in urinary luteinizing hormone concentrations of Male athletes in doping control analysis
Published 2019“…However, an adjustment of urinary LH concentrations by specific gravity based on a reference value of 1.020 seems to adequately correct the hyperhydration-induced decrease on the LH levels. - 2019 Human Kinetics, Inc.…”
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Mangifera indica L. kernel ethanol extract inhibits cell viability and proliferation with induction of cell cycle arrest and apoptosis in lung cancer cells
Published 2024“…Furthermore, the extract exhibited higher toxicity towards NCI-H292 cells, followed by A549 and normal MRC-5 cells in decreasing order of potency. …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. …”
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