Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Effect of zirconia nanotube coating on the hydrophilicity and mechanochemical behavior of zirconium for biomedical applications by Nezhad, Erfan Zal

“…Wear tests performed on bare and coated substrates revealed that the coated samples annealed at 400 °C had a significantly lower average coefficient of friction than the other substrates. …”
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Unanswered issues on decarbonizing the aviation industry through the development of sustainable aviation fuel from microalgae by Rony, Zahidul Islam

“…Fuel consumer behavior is also heavily influenced by factors such as fluctuating fuel prices and the need for a consistent and reliable fuel supply. Microalgae fuel is gaining popularity in the aviation industry as a potential source of energy diversification. …”
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Computational modeling of motile cilia generated cerebral flow dynamics in zebrafish embryo by Salman, Huseyin Enes

“…Background: Motile cilia are hair-like microscopic structures which move the fluids along the epithelial surfaces. Cilia cover a wide range of regions in the nervous system, such as the nasal cavity, spinal cord central canal, and brain ventricles. …”
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Concentrated Solar Power Plant for Key Locations in Doha Qatar by Elbeh, Mutaz Bargas

“…Thus, solar renewable energy technologies and concentrating solar power (CSP) has a good potential for producing green energy in Qatar. …”
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Investigation of gas-liquid flow using electrical resistance tomography and wavelet analysis techniques for early kick detection by Barooah, Abinash

“…Gas kick is a well control problem and is defined as the sudden influx of formation gas into the wellbore. …”
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SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs by Shalaby, Raed

“…The present study describes the synthesis of a series of 22 chalcone analogs. These compounds were evaluated as potential human MAO-A and MAO-B inhibitors. …”
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Surface Roughness Modelling of the Micromechanically Patterned CNT Forests by Mohd Razib , Mohd Asyraf

“…Introduction: A new method of modelling surface roughness of the resultant structure from various parameters in the microforming of CNT forests has been developed. …”
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Trends of use of SGLT2 inhibitors in Qatar by Zaghloul, Nancy

“…Background: Type 2 diabetes mellitus (T2DM) represents a growing health challenge in Qatar and worldwide. …”
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Effect of reinforcement concentration on the properties of hot extruded Al-Al2O3 composites synthesized through microwave sintering process by Reddy, M. Penchal

“…Results showed that, as the content of hard ceramic particles increases, it improves overall mechanical properties including microhardness, 0.2% yield strength, ultimate compression/tensile strength, and Young's modulus while the ductility and co-efficient of thermal expansion decreases. XRD patterns and SEM/EDS mapping images show a uniform distribution of Al2O3 particles in the Al matrix. …”
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Event-triggered based consensus of autonomous underactuated surface vessels by Mirzaei, Morteza

“…Unactuated and actuated states of considered vehicles are strongly coupled, hence a state transformation is utilized to represent the vehicle model in a cascade nonlinear system format, and consequently switching controllers are designed to make the vehicles to reach a consensus. …”
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The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe by Ammari, Lora

“…This research indicates a positive correlation between living alone and loneliness, with a greater effect on males, and identifies loneliness as an independent factor decreasing QoL. …”
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Nutritional quality and health risk of pepper fruit as affected by magnesium fertilization. by Lu, Ming

“…As a result, Mg fertilization decreased the comprehensive nutrition level of pepper by 16.6%. …”
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Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar by Abdelrahman, Doua

“…Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. Studies related to B19V prevalence in the Middle East and North Africa (MENA) region and other parts of Asia are very scarce. …”
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Iron Sulfide Scale Inhibition in Carbonate Reservoirs by Gasimli, Nijat

“…A scale inhibitor solution is introduced into a formation by applying a squeeze treatment. …”
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Dynamic Salmonella Enteritidis biofilms development under different flow conditions and their removal using nanoencapsulated thymol by Yammine, Jina

“…ML nanocapsules decreased significantly bacterial counts during the first 0.5 h, while LBL nanocapsules eliminated the remaining bacterial cells and ensured a protection from bacterial contamination for up to 5 h by releasing THY in a sustained manner over time due to the thicker shell wall structure.…”
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Effect of surfactants on the convective heat transfer and pressure drop characteristics of ZnO/DIW nanofluids: An experimental study by Qamar, Adnan

“…Convective heat transfer (HTC) and flow characteristics (pressure drop (ΔP) and friction factor (f)) of aqueous ZnO NFs' within a circular mini tube (Di = 1.0 mm, L = 330 mm) were analyzed. …”
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An enhanced performance IPT based battery charger for electric vehicles application by Abdelhamid, E.

“…IPT system has proved its capability to be a safe, convenient, and efficient electric vehicle battery charger through its features, such as operating in a harsh environment, high efficiency at reasonable power levels, and decreasing equipment maintenance through operating without any mechanical contacts. …”
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Changes in Dietary Habits and Eating Behaviors during COVID-19 Induced Confinement by alnatsheh, reem bassim

“…Among these changes, increased (p<0.05) prevalence of fruit and vegetable, immune boosters, water, and hot beverage consumption as well as decreased (p<0.05) eating in restaurants and fatty food consumption, suggesting a positive change. …”
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Microbiota-derived acetate activates intestinal innate immunity via the Tip60 histone acetyltransferase complex by Bat-Erdene, Jugder

“…Reduced expression of the histone acetyltransferase Tip60 decreased IMD signaling and blocked rescue by dietary acetate and other sources of intracellular acetyl-CoA. …”
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