Kit-mediated autophagy suppression driven by a viral oncoprotein emerges as a crucial survival mechanism in Merkel cell carcinoma by Hao Shi (158171)

“…</p> <p><b>Abbreviation</b>: 3-MA, 3-methyladenine; AL, autolysosome; AP, autophagosome; Baf-A1, bafilomycin A₁; BARA, β-α repeated autophagy specific domain; BH3, BCL2 homology 3 domain; CCD, coiled-coil domain; CHX, cycloheximide; Co-IP, co-immunoprecipitation; CQ, chloroquine; CTR, control; DAPI, 4′,6-diamidino-2-phenylindole; EBSS, Earle’s balanced salt solution; ECD, evolutionarily conserved domain; EEE, three-tyrosine phosphomimetic mutations Y229E Y233E Y352E; ER, endoplasmic reticulum; FFF, three-tyrosine non-phosphomimetic mutations; FFPE, formalin-fixed paraffin-embedded; FL, full-length; GIST, gastrointestinal stromal tumor; IB, immunoblotting; IHC, immunohistochemistry; KIT-HEK293, KIT stably expressing HEK293 cells; KRT20/CK20, keratin 20; LT, large T-antigen; LT339, MCPyV truncated LT antigen; LTco, codon-optimized MCPyV LT antigen; MCC, Merkel cell carcinoma; MCPyV⁻, MCPyV-negative; MCPyV, Merkel cell polyomavirus; MCPyV⁺, MCPyV-positive; PARP1, poly(ADP-ribose) polymerase 1; PCI, pan-caspase inhibitor; PI, propidium iodide; PtdIns3K, class III phosphatidylinositol 3-kinase; PtdIns3P, phosphatidylinositol-3-phosphate; RB1, RB transcriptional corepressor 1; RTKs, receptor tyrosine kinases; KITLG/SCF, KIT ligand; sT, small T-antigen; sTco, codon-optimized MCPyV sT antigen; T-B, Tat-BECN1; T-S, Tat-scrambled; TEM, transmission electron microscopy.…”

Estimated marginal mean values representative of the inter-positional differences in average time on ball and the relative frequency of ball touches and releases per minute of matc... by Emily Escreet (20552634)

Piecewise linear mixed effects regression statistics with comparison between the dengue and other febrile illness (OFI) groups. by Baptiste Vasey (8981180)

Resveratrol decreases CYP17A1 and CYP21A2 protein expression. by Nesa Marti (3851059)

“…<p>A. Gene expression profiling by qRT-PCR was performed for CYP17, CYP21 and their cofactor POR in H295R cells grown under normal conditions (GM), starvation conditions (SM), metformin (Met) (1mM) treatment and under resveratrol (RSV) (5<u>μM)</u> treatment. …”

Cells with higher expression of a housekeeping gene have a decreased expression of viral genes. by Efrat M. Cohen (3384470)

A genetic variant in human FIRE is associated with a decreased interferon response in myeloid cells. by Anaïs Assouvie (9600529)

A low dose of BCNU decreases division and promotes differentiation of O-2A/OPCs by Joerg Dietrich (35101)

A hypoglycaemic <i>milieu</i> decreases NCS viability in a dose-dependent manner. by Shiva Mansouri (2838086)

Histopathological examination of MSCs and short-term cyclosporine A (CsA) decreases allotransplant rejection. by Yur-Ren Kuo (325023)

DSB repair capacity decreases with age in non-induced lymphocytes of healthy individuals. by Sandrine Lacoste (542600)

Time-resolved EELS spectra, as a function of decreasing water vapor pressure. by Cathal Cassidy (1758703)

<i>Syx5</i> suppression in human cells decreases copper accumulation but does not affect rate of turnover. by Melanie Norgate (234832)

The mean contact distance between bulk soil and pores scales exponentially with decreasing porosity during soil compaction. by Steffen Schlüter (2889014)

Over expression of hnRNP A1 decreases and hnRNP F increases inclusion of exon 11 of an <i>INSR</i> minigene, whereas knockdown of endogenous hnRNP F and hnRNP A1 has the opposite effect. by Indrani Talukdar (195204)

Subjects:

Activation of NMDA receptors with D-serine obviously limited the decrease of p-CREB in the hippocampus of the surviving LPS-treated mice. by Shuibing Zhang (4336402)

Infection of B6 mice with wild type <i>B</i>. <i>hermsii</i> and <i>Bh</i>Δ<i>dam</i> at decreasing infectious doses of approximately 1 x 10⁵ to 10 spirochetes. by Allison E. James (2794606)

Chronic <i>Trichuris muris</i> Infection Decreases Diversity of the Intestinal Microbiota and Concomitantly Increases the Abundance of Lactobacilli by Jacob Bak Holm (734935)

The flexural lumber properties of Pinus patula Schiede ex Schltdl. & Cham. improve with decreasing initial tree spacing by Justin Erasmus (8702619)

“…<p dir="ltr">Rapid growth rates and reduced harvesting ages of South African-grown pine plantations have caused a reduction in the stiffness of structural lumber, which accounts for about 75% of all sawn wood. …”

Cells lacking Cbf11 and/or Mga2 display nutrient-responsive decrease in lipid droplet (LD) content. by Anna Marešová (14375187)

Adenosine decreases the number of releasable vesicles and release probability without changing the rate of recovery from vesicle depletion. by Shouping Wang (402959)

“…For each cell, the last 6 EPSC amplitudes were fit with a linear regression line and extrapolated to time 0 to estimate the readily releasable pool size (<i>Nq</i>). …”