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large decrease » marked decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
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224141
Table_1_10-Hydroxydec-2-Enoic Acid Reduces Hydroxyl Free Radical-Induced Damage to Vascular Smooth Muscle Cells by Rescuing Protein and Energy Metabolism.XLSX
Published 2022“…To the best of our knowledge, our results provide the first concrete evidence that 10-HDA-scavenged •OH could be a potential pharmacological application for maintaining vascular health.…”
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224142
DataSheet1_Activation of Nrf2 by Lithospermic Acid Ameliorates Myocardial Ischemia and Reperfusion Injury by Promoting Phosphorylation of AMP-Activated Protein Kinase α (AMPKα).ZIP...
Published 2021“…<p>Background: As a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, lithospermic acid (LA) has been identified as the pharmacological management for neuroprotection and hepatoprotection. …”
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224143
Image4_2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside ameliorates bleomycin-induced pulmonary fibrosis via regulating pro-fibrotic signaling pathways.jpg
Published 2022“…The main purpose of this study was to investigate the protective effect of THSG against bleomycin (BLM)-induced lung fibrosis in a murine model, and explore the underlying mechanisms of THSG in transforming growth factor-beta 1 (TGF-β1)-induced fibrogenesis using MRC-5 human lung fibroblast cells. …”
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224144
DataSheet_3_The value of metabolic LncRNAs in predicting prognosis and immunotherapy efficacy of gastric cancer.docx
Published 2023“…Introduction<p>As a unique feature of malignant tumors, abnormal metabolism can regulate the immune microenvironment of tumors. …”
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224145
Physiological and transcriptomic responses of Lanzhou Lily (<i>Lilium davidii</i>, var. unicolor) to cold stress
Published 2020“…Comparative transcriptome profiling showed that a total of 238,109 differentially expressed genes were detected. …”
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224146
Synthesis and Characterization of Ru(II)–DMSO–Cl–Chalcone Complexes: DNA Binding, Nuclease, and Topoisomerase II Inhibitory Activity
Published 2012“…The molecular assembly of complex <b>5</b> using secondary interactions provides a butterfly structure. The binding of complexes with calf thymus DNA is monitored using UV–vis spectral titrations. …”
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224147
Table_1_Molecular Mechanism of the UDP-Glucuronosyltransferase 2B20-like Gene (AccUGT2B20-like) in Pesticide Resistance of Apis cerana cerana.XLSX
Published 2020“…<p>UDP-glucuronosyltransferases (UGTs), being multifunctional detoxification enzymes, play a major role in the process of resistance to various pesticides in insects. …”
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224148
Data_Sheet_1_Alpine wetland degradation reduces carbon sequestration in the Zoige Plateau, China.docx
Published 2022“…These results suggest that the capacity of carbon sequestration in the Zoige wetlands reduced with intensification of the degradation. This study provides a reference for sustainably managing and utilizing degraded wetlands under climate change.…”
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224149
DataSheet1_Clostridium butyricum Protects Against Pancreatic and Intestinal Injury After Severe Acute Pancreatitis via Downregulation of MMP9.ZIP
Published 2022“…In addition, to investigate the association between gut microbiota and MMP9 in intestinal injury during SAP, we established MMP9 stable knockdown Caco2 and HT29 cells in vitro and generated a MMP9 knockout (MMP9−/−) mouse model of SAP in vivo.…”
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224150
Substitution of dry corn grain by rehydrated and ensiled corn grain, finely or coarsely ground, on performance of young bulls finished in feedlot
Published 2022“…The experiment was conducted in blocks by weight, and bulls were randomly assigned into four groups of five animals each in a 2 × 2 factorial scheme. The factors evaluated were particle size (finely and coarsely ground) and two grain sources (dry ground corn and rehydrated corn grain silage). …”
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224151
Expression of lncRNA RGMB-AS1 and RGMB in lung adenocarcinoma tissues.
Published 2016“…<p>(A) LncRNA RGMB-AS1 expression in lung adenocarcinoma tissues (Tumor group) was higher than in adjacent normal tissues (Normal group) (<i>P</i> < 0.05). …”
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224152
DataSheet_2_Global burden of major gastrointestinal cancers and its association with socioeconomics, 1990–2019.pdf
Published 2022“…</p>Conclusion<p>There is a profound association between socioeconomics and burden of common cancers of the gastrointestinal tract. …”
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224153
Shrimp allergen extract (SAE) immunotherapy preventing the development of allergies.
Published 2024“…SAE desensitization successfully decreased transcription of (A) <i>FcεR1α</i> mRNA (n = 6 mice per group) and (B) IL-4 mRNA—relative to NC—in the ileal tissue (n = 3 mice per group), and suppressed the production of the pro-inflammatory cytokine (C) IL-4 in serum (n = 6 mice per group). …”
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224154
Image_1_Integrative Analysis of LGR5/6 Gene Variants, Gut Microbiota Composition and Osteoporosis Risk in Elderly Population.tif
Published 2021“…The rs10920362 CT/TT genotype associated with a decreased relative abundance of Actinobacteria (β = −1.32, P < 0.001), Bifidobacteriaceae (β = −1.70, P < 0.001), and Bifidobacterium (β = −1.70, P < 0.001) compared to the CC genotype.…”
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224155
Image 1_Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus.pdf
Published 2025“…CD8<sup>+</sup> T naïve (Tn) cell MMP-Low, CD8<sup>+</sup> T effector memory cell MMP-Low, CD8<sup>+</sup> T central memory (Tcm) cell MMP-Low, and SCMM-CD8<sup>+</sup> Tn cells demonstrated a moderate diagnostic value for SLE, with an area under the curve (AUC) above 0.8. …”
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224156
The results of the microarray analysis revealed the GATA3-regulated cytokine and cytokine receptor genes in Th2 cells.
Published 2013“…<p>(<b>A</b>), The names of the selected 24 cytokine genes. …”
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224157
Data_Sheet_1_Pyruvate Might Bridge Gut Microbiota and Muscle Health in Aging Mice After Chronic High Dose of Leucine Supplementation.docx
Published 2021“…</p><p>Conclusions: Chronic high dose of leucine supplementation changed gut microbiota composition and increased pyruvate levels in the feces, which possibly provides a novel direction for promoting muscle health in aging mice.…”
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224158
Table_1_Carbon Amendments Influence Composition and Functional Capacities of Indigenous Soil Microbiomes.XLSX
Published 2020“…Mesocosms were established with soil from two field sites varying in soil organic matter content (low organic matter, LOM; high organic matter, HOM), that were amended at intervals over nine months with low or high dose solutions of glucose, fructose, malic acid, a mixture of these compounds, or water only (non-amended control). …”
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224159
Small molecule inhibitors of GSK-3β impede VEEV replication.
Published 2012“…<p><b>A</b>) U87MG astrocytes were treated with BIO (10, 5, 2.5, or 1.25 µM) and cell viability assayed 24 hours later by CellTiter Glo Assay (Promega). …”
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224160
Image9_Single-cell transcriptome dynamics of the autotaxin-lysophosphatidic acid axis during muscle regeneration reveal proliferative effects in mesenchymal fibro-adipogenic progen...
Published 2023“…<p>Lysophosphatidic acid is a growth factor-like bioactive phospholipid recognising LPA receptors and mediating signalling pathways that regulate embryonic development, wound healing, carcinogenesis, and fibrosis, via effects on cell migration, proliferation and differentiation. …”