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large decrease » marked decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
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224621
Influence of let-7b on cell proliferation and apoptosis.
Published 2012“…<p><b>A</b>, proliferation assay via Cell-Light™ EdU DNA Cell Proliferation Kit showing decreased proliferation rate of MDA-MB-435 and SK-MES-1 cells treated with let-7b compared to the cells treated with random let-7b or control. …”
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224622
Table 4_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.xlsx
Published 2024“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”
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224623
DataSheet2_Lateral impact response of circular hollow steel tubes with mid-span localized penetrating notches.docx
Published 2023“…The results showed that under a lateral impact load, the mid-span of the CHST column presented global bending failure patterns accompanied by local indentation deformation in the impact region and local buckling deformation at the bottom of the fixed end. …”
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224624
Data_Sheet_1_RETRACTED: Endothelial-Monocyte Activating Polypeptide II Suppresses the In Vitro Glioblastoma-Induced Angiogenesis by Inducing Autophagy.DOCX
Published 2024“…<p>The obstacle in delivering therapeutics to glioblastoma (GBM) is tumor-induced angiogenesis which leads to the formation of abnormal vessels and a dysfunctional blood-tumor barrier. Here, we elucidated the effect of endothelial-monocyte activating polypeptide II (EMAP II) on the GBM-induced angiogenesis as well as its potential mechanisms. …”
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224625
DataSheet3_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.zip
Published 2021“…To investigate the effects of SQ, we established the experimental passive Heymann nephritis (PHN) rat model induced by anti-Fx1A antiserum in vivo and doxorubicin hydrochloride (ADR)-injured apoptotic podocyte model in vitro. …”
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224626
DataSheet1_Scutellarein ameliorates dextran sulfate sodium-induced ulcerative colitis by inhibiting colonic epithelial cell proinflammation and barrier disruption.DOC
Published 2024“…Introduction<p>Scutellarein (Scu) is a natural occurring flavonoid found in multiple traditional Chinese medicines such as Oroxylum indicum (L.) …”
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224627
Image_3_Effect of four fluoroquinolones on the viability of bladder cancer cells in 2D and 3D cultures.tif
Published 2023“…</p>Results and Discussion<p>All tested fluoroquinolones in 2D culture decreased the viability of both tested cell lines in a dose- and timedependent manner. …”
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224628
Table_1_Detection of BDNF-Related Proteins in Human Perilymph in Patients With Hearing Loss.XLSX
Published 2019“…These BDNF regulated proteins were correlated to the presence of residual hearing (RH) prior to implantation and to the performance data with the cochlear implant after 1 year. There was overall a decreased level of expression of BDNF-regulated proteins in profoundly hearing-impaired patients compared to patients with some RH. …”
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224629
Data_Sheet_1_SIRT6 Promotes Osteogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells Through Antagonizing DNMT1.docx
Published 2021“…Sirtuin protein 6 (SIRT6) is a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase that plays important roles in cell differentiation. …”
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224630
Elements including metals in the atomizer and aerosol of disposable electronic cigarettes and electronic hookahs
Published 2017“…</p><p>Conclusion</p><p>These data show that EC/EH aerosols contain a mixture of elements, including heavy metals, with concentrations often significantly higher than in conventional cigarette smoke. …”
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224631
Data_Sheet_1_Effective enhancement of the immunomodulatory capacity of canine adipose-derived mesenchymal stromal cells on colitis by priming with colon tissue from mice with colit...
Published 2024“…</p>Methods<p>The capacity of canine adipose-derived MSCs (cADSCs) primed with colon tissue homogenates from mice with experimentally induced colitis or a combination of tumor necrosis factor-α and interferon-γ to inhibit T-cell proliferation was analyzed, along with their own apoptosis, proliferation, cell surface marker expression, and transcriptome. …”
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224632
Table 2_Anti-Müllerian hormone, sex steroids, and metabolic profile in cord blood of pregnancies with type 2 diabetes and gestational diabetes.docx
Published 2025“…Only pregnancies carrying a female offspring were included. AMH, sex steroids, and metabolic function biomarkers, including glucose, insulin, IGF-1, and adiponectin (APN) were measured. …”
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224633
Data_Sheet_1_Suppression of Phytochrome-Interacting Factors Enhances Photoresponses of Seedlings and Delays Flowering With Increased Plant Height in Brachypodium distachyon.zip
Published 2021“…Therefore, this study determines a molecular mechanism underlying phytochrome-mediated PIF regulation in Brachypodium, i.e., sequestration, and also elucidates the functions of BdPIL1 and BdPIL3 in the growth and development of the monocot plant.…”
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224634
Image_1_Hypoxia-Inducible Factor 1α and 2α Have Beneficial Effects in Remote Ischemic Preconditioning Against Stroke by Modulating Inflammatory Responses in Aged Rats.TIF
Published 2020“…ACF also reversed the activation of the Akt signaling pathway induced by RIPC following stroke. HIF may play a key role in RIPC, which was likely mediated by the Akt signaling pathway and systemic modulation of the inflammatory response in aged rats.…”
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224635
Thymosin Beta 4 Protects Cardiomyocytes from Oxidative Stress by Targeting Anti-Oxidative Enzymes and Anti-Apoptotic Genes
Published 2012“…<div><h3>Background</h3><p>Thymosin beta-4 (Tβ4) is a ubiquitous protein with many properties relating to cell proliferation and differentiation that promotes wound healing and modulates inflammatory mediators. …”
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224636
The GOAT-Ghrelin System Is Not Essential for Hypoglycemia Prevention during Prolonged Calorie Restriction
Published 2012“…<div><h3>Objective</h3><p>Ghrelin acylation by ghrelin O-acyltransferase (GOAT) has recently been reported to be essential for the prevention of hypoglycemia during prolonged negative energy balance. Using a unique set of four different genetic loss-of-function models for the GOAT/ghrelin/growth hormone secretagogue receptor (GHSR) system, we thoroughly tested the hypothesis that lack-of-ghrelin activation or signaling would lead to hypoglycemia during caloric deprivation.…”
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224637
Image_2_Peri-interventional Triple Therapy With Dabigatran Improves Vasomotion and Promotes Endothelialization in Porcine Coronary Stenting Model.TIF
Published 2021“…<p>Objective: We evaluated the short and long-term effect of peri-interventional dabigatran therapy on vasomotion, endothelialization, and neointimal formation in a porcine coronary artery stenting model.</p><p>Background: Stenting of coronary arteries induces local inflammation, impairs vasomotion and delays endothelialization.…”
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224638
Targeted Deletion of <em>Nrf2</em> Reduces Urethane-Induced Lung Tumor Development in Mice
Published 2011“…<div><p>Nrf2 is a key transcription factor that regulates cellular redox and defense responses. …”
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224639
Image_1_Residual OXPHOS is required to drive primary and metastatic lung tumours in an orthotopic breast cancer model.tif
Published 2024“…Background<p>Fast adaptation of glycolytic and mitochondrial energy pathways to changes in the tumour microenvironment is a hallmark of cancer. Purely glycolytic ρ<sup>0</sup> tumour cells do not form primary tumours unless they acquire healthy mitochondria from their micro-environment. …”
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224640
Table_3_Genome-Wide Analysis of NF-Y Genes in Potato and Functional Identification of StNF-YC9 in Drought Tolerance.docx
Published 2021“…However, little is known about this family in potato. In the present study, a total of 41 StNF-Y genes were identified in the potato genome. …”