Data_Sheet_1_Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells.xlsx by Souvarish Sarkar (8382513)

“…We validated progranulin (PGRN) as a lysosomal PD-associated protein that is downregulated by αSyn_Agg in microglia in-vivo and is expressed by microglia in post-mortem PD brain, congruent with our in vitro findings.…”

Image_2_Suppression of weed and insect populations by living cover crop mulches in organic squash production.jpg by Dylan Bruce (13913982)

“…Living mulches of Dutch white clover (Trifolium repens), annual ryegrass (Lolium multiflorum), and a mix of Dutch white clover and annual ryegrass were compared with full tillage cultivated ground and straw mulch controls for effect on yield, fruit marketability, weed and pest counts, and weed management time. …”

Immunization with an ApoB-100 Related Peptide Vaccine Attenuates Angiotensin-II Induced Hypertension and Renal Fibrosis in Mice by Tomoyuki Honjo (539273)

“…CD8+ T cells from p210 immunized mice displayed a different phenotype compared to CD8+ T cells from unimmunized controls. …”

Data Sheet 1_RvD2 mitigates TNFɑ-Induced mitochondrial reactive oxygen species through NRF2 signaling in placental trophoblasts.pdf by Taija Hahka (20983223)

“…</p>Discussion<p>These findings demonstrate that RvD2 functions as a positive regulator of endogenous antioxidant properties by enhancing NRF2 levels and mitigating mitochondrial ROS in placental trophoblasts.…”

DataSheet_1_Integration of Inflammation-Immune Factors to Build Prognostic Model Predictive of Prognosis and Minimal Residual Disease for Hepatocellular Carcinoma.pdf by Xin Xu (11989)

“…Background<p>Tumor recurrence after hepatectomy is high for hepatocellular carcinoma (HCC), and minimal residual disease (MRD) could be the underlying mechanism. A predictive model for recurrence and presence of MRD is needed.…”

Table_1.DOCX by Wei-Di He (4920472)

“…To investigate the early cold stress response of Dajiao, here we applied comparative membrane proteomics analysis for both cold-sensitive Cavendish and cold-tolerant Dajiao bananas subjected to cold stress at 10°C for 0, 3, and 6 h. A total of 2,333 and 1,834 proteins were identified in Cavendish and Dajiao, respectively. …”

Effect of recombinant human keratinocyte growth factor in inducing Ras–Raf–Erk pathway-mediated cell proliferation in emphysematous mice lung by Jai Prakash Muyal (7494032)

“…Hence, rHuKGF may prove to be a potential drug in the treatment of emphysema.…”

Myeloid cell comparison. by Xiaoke Xu (3468623)

“…This infection can lead to neurological effects and establish a viral reservoir. Given the gaps in our understanding of how these cells respond <i>in vivo</i> to acute CNS infection, we conducted single-cell RNA sequencing (scRNA-seq) on myeloid cells from the brains of three rhesus macaques 12 days after SIV infection, along with three uninfected controls. …”

Table_1_High-Throughput Analysis of Water-Soluble Forms of Choline and Related Metabolites in Human Milk by UPLC-MS/MS and Its Application.DOCX by Daniela Hampel (683851)

“…In order to enable the rapid assessment of choline intake for exclusively breastfed infants and to further investigate the associations between milk choline and maternal and infant status and other outcomes, we have developed a simplified method for the simultaneous analysis of human milk choline, glycerophosphocholine, phosphocholine, and the less abundant related metabolites betaine, carnitine, creatinine, dimethylglycine (DMG), methionine, and trimethylamine N-oxide (TMAO) using ultraperformance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS). …”

Data Sheet 1_Relay intercropped soybean promotes nodules development and nitrogen fixation by root exudates deposition.docx by Ping Lin (146330)

“…This study was conducted to investigate the relationship between crop root exudates and soybean nodule development under intercropping patterns.</p>Method<p>A two years field experiments was carried out and combined with pot experiments to quantify the effects of planting mode, i.e., relay intercropping and monocropping, and genotypes, i.e., supernodulating NTS1007(NTS), Nandou-12(ND) and Guixia-3(GX) on root exudates, rhizobium community structure, nodule development and nitrogen fixation ability.…”

Enhanced immunity against SARS-CoV-2 in returning Chinese individuals by Runyu Yuan (11843324)

“…Blood and throat swab specimens were collected from participants, and their immunity status was determined through competitive ELISA, microneutralization assay and enzyme-linked FluoroSpot assay. A total of 272 subjects were involved in the questionnaire survey, of whom 235 (86.4%) were returning Chinese individuals and 37 (13.6%) were foreigners. …”

Image_1_Femtosecond laser-assisted arcuate keratotomy for the management of corneal astigmatism in patients undergoing cataract surgery: Comparison with conventional cataract surge... by Hyunmin Ahn (3821782)

“…</p>Design<p>Retrospective comparative interventional case series.</p>Methods<p>A total of 2,498 eyes of consecutive patients who presented with 3.00 diopters (D) or under of astigmatism were included. …”

Table_1_Chromatin Remodeling Protein ZmCHB101 Regulates Nitrate-Responsive Gene Expression in Maize.xlsx by Xinchao Meng (8444169)

“…Here, we demonstrate that ZmCHB101 plays a pivotal regulatory role in nitrate-responsive gene expression. …”

DataSheet_1_Coexpression of HHLA2 and PD-L1 on Tumor Cells Independently Predicts the Survival of Spinal Chordoma Patients.docx by Chao Xia (1799434)

“…</p>Conclusion<p>These data provide a better understanding of the immunosuppressive mechanism in chordoma and may be useful for the development of combination or novel immunotherapy approaches aiming to improve therapeutic efficacy and survival.…”

Data_Sheet_1_Antioxidant Activity and the Potential Mechanism of the Fruit From Ailanthus altissima Swingle.CSV by Ya-nan Mo (11829002)

“…<p>The fruits of Ailanthus altissima Swingle (AS) possess a variety of pharmacological activities. Its antioxidant activity and the potential mode of action have not yet been investigated. …”

Image_1_Intermittent Fasting Reshapes the Gut Microbiota and Metabolome and Reduces Weight Gain More Effectively Than Melatonin in Mice.tif by Jingliang Liu (1870555)

“…</p><p>Objective: This study aimed to investigate the effects of IF on body fat and the gut microbiota and metabolome as well as a potential interaction with melatonin.</p><p>Methods: Male C57BL/6J mice (23.0 ± 0.9 g, 6 wk old) were randomly assigned into four groups (12 mice/group): control (C), intermittent fasting (F), melatonin (M), and intermittent fasting plus melatonin (MF). …”

Disease-associated mutations in human <i>TUBB3</i> disturb netrin repulsive signaling by Qiangqiang Shao (6866576)

“…<div><p>Missense mutations in the human <i>TUBB3</i> gene cause a variety of neurological disorders associated with defects in axon guidance and neuronal migration, but the underlying molecular mechanisms are not well understood. …”

DataSheet2_Salvia chinensia Benth induces autophagy in esophageal cancer cells via AMPK/ULK1 signaling pathway.ZIP by Lei Jia (303610)

“…<p>Salvia chinensia Benth (Shijianchuan in Chinese, SJC) has been used as a traditional anti-cancer herb. SJC showed good anti-esophageal cancer efficacy based on our clinical application. …”

DataSheet_1_Analysis of Adaptive Olaparib Resistance Effects on Cisplatin Sensitivity in Triple Negative Breast Cancer Cells.docx by Ambikai Gajan (3437534)

“…OlaR TNBC cells express decreased levels of PARP-1 and Pol η, a translesion-synthesis polymerase important in platinum-induced interstrand crosslink repair. …”

Image_2_Deletion of Non-histidine Domains of Histidine Kinase CHK1 Diminishes the Infectivity of Candida albicans in an Oral Mucosal Model.TIF by Yahui Feng (3897082)

“…</p>Methods<p>The domain mutants CHK25 (^ΔS_TkcCHK1/Δchk1) and CHK26 (^ΔS_TkcΔgafCHK1/Δchk1) were first constructed by the his1-URA3-his1 method and confirmed by sequencing and Southern blots. A mouse tongue infection model was used to evaluate the hyphal invasion and fungal loads in each domain mutant, full-gene deletion mutant CHK21 (chk1Δ/chk1Δ), re-constituted strain CHK23 (chk1Δ/CHK1), and wild type (WT) from day 1 to day 5. …”