Long-noncoding RNA HOXA transcript at the distal tip ameliorates the insulin resistance and hepatic gluconeogenesis in mice with gestational diabetes mellitus via the microRNA-423-... by Qianqian Cao (7309022)

“…The relations among HOTTIP, miR-423-5p and WNT7A were validated. HOTTIP and WNT7A levels were decreased while miR-423-5p was elevated in GDM mice. …”

Heatmap of orthologs of known dauer genes in different life stages of <i>R</i>. <i>diutinus</i>. by Alex Dulovic (6528617)

“…Z score indicates difference in expression between the different stages, with blue indicating a negative z score (-2 to 0) and decreased expression and red indicating a positive z score (0 to 2) and increased expression.…”

DataSheet_1_WWOX-rs13338697 genotype predicts therapeutic efficacy of ADI-PEG 20 for patients with advanced hepatocellular carcinoma.docx by Yu-De Chu (817159)

“…Silencing WWOX to mimic low WWOX protein expression in HCC in patients with the WWOX-rs13338697-GG genotype, enhanced HIF1A increment under hypoxia, further decreased ASS1, and increased cell susceptibility to ADI-PEG 20.…”

The effects of A1M-treatment on gene expression in white blood cells, placenta and kidney tissue. by Lena Wester-Rosenlöf (515985)

“…The median value of the starved+placebo group was set to 100% and the results are expressed as percentage of the median value. The A1M treatment caused significant increase in SOD2 mRNA expression in white blood cells (p = <0.043) and a decreased expression of s-Flt1 mRNA (p = <0.012). …”

Expression of <i>Foxf1a</i> and <i>Foxf2</i> in <i>shh^−/−</i> and <i>Tbx5^+/−</i> mutants embryos at E9.5. by Andrew D. Hoffmann (651875)

“…<i>Tbx5</i> heterozygotes expressed <i>Foxf1a</i> at decreased levels specifically in the posterior SHF tissues (C, D), whereas <i>Foxf2</i> expression patterns were unchanged (G, H). …”

Biased qPCR results for medium-copy <i>HOX</i> transcripts after Whole Transcriptome Amplification (WTA). by Carolin Coenen (815878)

“…<p>Similar to RT-PCR analysis, the same cDNA of the respective human bone marrow-derived multipotent stromal cell (BM-MSC) line (biological triplicates, n = 3) synthesized by standard reverse transcription (RT samples) and Whole Transcriptome Amplification (WTA samples) was used for qPCR analysis. (A-C) The WTA samples revealed a significantly decreased expression level of the medium-copy <i>HOX</i> genes like <i>HOXA9</i>, <i>HOXB7</i> and <i>HOXD8</i> in comparison to RT samples. …”

Expression level of <i>HOX</i> genes in human bone marrow-derived multipotent stromal cells (BM-MSCs). by Carolin Coenen (815878)

“…<p>The expression level of seven medium-, and low copy <i>HOX</i> transcripts is documented for biological and technical replicates of BM-MSC lines (n = 3) by 2^-ΔCT value related to <i>GAPDH</i>. (A) <i>HOX</i> genes are weakly expressed in human BM-MSCs compared to high-copy transcripts like <i>RPL13A</i> showing an expression level of about 10⁻¹ related to <i>GAPDH</i>. …”

Protective functions of G-CSF in combination stimulus depends on activity of MAPK and Akt signaling cascades. by Jingjing Su (718308)

“…<p>The addition of ERK1/2 or Akt inhibitors (30 nM PD98059, 20 μM LY294002) 30 min before combination stimulus almost completely abrogated the protective functions of G-CSF (100 nM) following combination stimulus by decreasing cell viability (A) and increasing caspase-3 activity (B). …”

The effect of glibenclamide on channel activity at +20, 0 and -20 mV. by Sajjad Salari (736104)

“…The addition of 50 μM glibenclamide resulted in a decreased current jump amplitude and a reduction in P_o. 100 μM glibenclamide caused a total channel inhibition at +20 and 0 mV (n = 5), but was ineffective at -20 mV. …”

Downregulation of Th1 response by co-infusion of donor-derived MSCs and Treg cells in aGVHD model. by Eun-Sol Lee (737390)

“…<p>(A) Th1 and Th2 cells were examined by flow cytometry at 12 days after BMT. …”

Transcriptional profiling of SHF from <i>shh^−/−</i> embryos. by Andrew D. Hoffmann (651875)

“…<p>(A) Microdissection for isolation of SHF tissues. …”

DNA damage checkpoint recovery in <i>Bacillus subtilis</i>. by Peter E. Burby (619463)

“…After DNA repair is complete and YneA expression decreases, YneA is cleared and cell division proceeds.…”

<i>siRBBP6</i> transfection into gastric cancer cells. by Tamami Morisaki (656222)

“…<p>(A), OCUM-12/SP and OCUM-2MD3/SP showed higher level of <i>RBBP6</i> mRNA expression than their parent cells, OCUM-12 and OCUM-2MD3. …”

DataSheet1_The crosstalk between MYC and mTORC1 during osteoclastogenesis.pdf by Seyeon Bae (740790)

“…The mammalian target of rapamycin (mTOR) is a kinase, and aberrant mTOR complex 1 (mTORC1) signaling is associated with altered bone homeostasis. …”

Acute D3 treatment conveys STM impairment that mainly affects hippocampal-dependent spatial memory consolidation. by Sylvia Josephy-Hernandez (6871478)

“…<p><b>(A)</b> Mice were trained in the Morris Water Maze (MWM) with three trials per day for 5 consecutive days. …”

Reduction of IL-17 after co-administration of donor-derived MSCs and Treg cells. by Eun-Sol Lee (737390)

“…<p>Recipient mice were evaluated at different time points after BMT. (A) The percentage of CD4⁺ IL-17⁺ cells and CD4⁺ IL-6⁺ cells were identified by flow cytometry at 12 days after BMT (<i>n</i> = 6). …”

Table_1_Kinetic, Structural, and Mutational Analysis of Acyl-CoA Carboxylase From Thermobifida fusca YX.DOCX by Kiran-Kumar Shivaiah (9972827)

“…Mutating this D427 residue resulted in alterations in the substrate specificity of the TfAcCCase, increasing proficiency for carboxylating acetyl-CoA, while decreasing carboxylation proficiency with propionyl-CoA and butyryl-CoA. …”

Image_1_MiR-185-5p Protects Against Angiogenesis in Polycystic Ovary Syndrome by Targeting VEGFA.tif by Jingzan Wei (9121817)

“…<p>Polycystic Ovary Syndrome (PCOS) is a heterogeneous endocrine disease with high incidences in women of reproductive age. …”

table1_Regulatory Master Genes Identification and Drug Repositioning by Integrative mRNA-miRNA Network Analysis for Acute Type A Aortic Dissection.docx by Junjun Fang (10017167)

“…<p>Acute type A aortic dissection (ATAAD) is a life-threatening disease. …”

Proteomic Comparison of 3D and 2D Glioma Models Reveals Increased HLA‑E Expression in 3D Models is Associated with Resistance to NK Cell-Mediated Cytotoxicity by Weiqi He (698658)

“…The resistance of the 3D-cultured tumor cells to NK cell lysis was mediated by the HLA-E/NKG2A interaction because the administration of antibodies that block either HLA-E or NKG2A completely eliminated this resistance and significantly decreased tumor formation. …”