Neurotransmitter release profile for a CA3-CA1 synapse with a single active zone and seven docked vesicles. by Suhita Nadkarni (47927)

“…<p>(<b>A</b>) Release data histogram in 10 ms bins for a synapse with intrinsic release probability of p_r = 0.2 (48 channels at <i>l_c</i> = 250 nm). …”

The effect of CA1 administration of orexin-A on hippocampal expression of COX-2 and BDNF in a rat model of orofacial pain by Razieh Kooshki (5887496)

“…However, an increased expression of COX-2 and decreased expression of BDNF was observed in the hippocampus of animals that received capsaicin or SB-334867-A (80 nM) plus capsaicin. …”

Effect of High-pressure Torsion on Corrosion Behavior of a Solution-treated Al-Mg-Sc Alloy in a Saline Solution by Michelle Dias Alves Lage (7823684)

“…The passive current density decreased after HPT processing, indicating a more protective oxide layer was formed on the surface of the HPT-processed alloy. …”

Salutaxel, a Conjugate of Docetaxel and a Muramyl Dipeptide (MDP) Analogue, Acts as Multifunctional Prodrug That Inhibits Tumor Growth and Metastasis by Xiaoming Wen (1302228)

“…Salutaxel (<b>3</b>) is a conjugate of docetaxel (<b>7</b>) and a muramyl dipeptide (MDP) analogue. …”

Immunofluorescence staining of LDLR and AnxA2 in tissues of WT and <i>AnxA2</i>^−/− mice. by Nabil G. Seidah (148050)

“…The corresponding LDLR staining of <i>AnxA2^−/−</i> mice tissues is significantly decreased in the adrenal and ileum while it shows less variation in the liver (right panels).…”

Supplementary Material for: Untreated Classic Galactosemia – a rare cause of adult-onset progressive cerebellar ataxia: A case report. by Karafyllis I. (17918261)

“…An important finding that enabled us to solve the diagnostic conundrum was the elevated CDT levels in the lack of alcohol-related symptoms, which also occur in untreated carbohydrate metabolism disorders, sometimes with ataxia as a leading symptom. The decreased erythrocyte galactose-1-phosphate uridyltransferase (GALT) enzyme activity and the elevated erythrocyte galactose-1-phosphate (Gal-1P) concentration led to the final diagnosis of galactosemia, a rare metabolic disorder. …”

Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design by Gergő Dargó (3138048)

“…We also verified our findings by testing five modified analogues designed by structural considerations. Significant decreases in their HSA binding proved that the UV-pH titration method combined with an in silico support can be used as a medicinal chemistry tool to assist rational molecular design.…”

Unilateral acute posterior multifocal placoid pigment epitheliopathy in a patient with a strongly positive purified protein derivative test by Thiago Cabral (7367231)

“…<div><p>ABSTRACT A 27-year-old man presented with a complaint of decreased visual acuity in the right eye. …”

Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design by Gergő Dargó (3138048)

“…We also verified our findings by testing five modified analogues designed by structural considerations. Significant decreases in their HSA binding proved that the UV-pH titration method combined with an in silico support can be used as a medicinal chemistry tool to assist rational molecular design.…”

R code from Global warming intensifies the interference competition by a poleward-expanding invader on a native dragonfly species by Koki Nagano (17381329)

Overexpression of miR-195-3p and miR-206 does not significantly decrease Dicer 3’UTR expression in the absence of Mov10. by Monica C. Lannom (11772729)

Differential proteomes of WT and Δ<i>tktA</i>, Δ<i>rpe and ΔrpiA</i> mutants. by Héloise Rytter (11218693)

“…Proteins undergoing the same modulation in Δ<i>tktA</i>, Δ<i>rpe</i> and Δ<i>rpiA</i> mutants but not in Δ<i>talA</i> are highlighted in color (blue and red for decreased increased in the mutant, respectively).…”

The importance of electrotonic distance for burst firing and the impact of dendritic topology illustrated with a fully asymmetrical and a fully symmetrical tree. by Ronald A. J. van Elburg (80591)

“…Because the distance between soma and terminal segment is smaller in the symmetrical than in the asymmetrical tree, the membrane potential evolution in the symmetrical tree has less spatial differentiation, the membrane potential reaches a lower value at the distal end, and the distal membrane potential start decreasing earlier in time, so that the return current from dendrites to soma reaches the soma at a time when the delayed-rectifier K⁺ channels are still open, preventing the generation of a second spike. …”

Table_2_Is Gut Microbiota a Key Player in Epilepsy Onset? A Longitudinal Study in Drug-Naive Children.docx by Camilla Ceccarani (5892314)

“…In drug-naive subjects, we observed a microbial signature that shared several features with those reported in refractory epilepsy, such as an increased abundance in Akkermansia spp. and Proteobacteria and a decreased relative abundance in Faecalibacterium spp.We suggest that a bacterial-mediated proinflammatory milieu could contribute to seizure occurrence in children with new onset of epilepsy, as already reported for individuals with drug-resistant epilepsy, and that it could vary during treatment in those who are drug-responsive.…”

Image_1_Is Gut Microbiota a Key Player in Epilepsy Onset? A Longitudinal Study in Drug-Naive Children.tif by Camilla Ceccarani (5892314)

“…In drug-naive subjects, we observed a microbial signature that shared several features with those reported in refractory epilepsy, such as an increased abundance in Akkermansia spp. and Proteobacteria and a decreased relative abundance in Faecalibacterium spp.We suggest that a bacterial-mediated proinflammatory milieu could contribute to seizure occurrence in children with new onset of epilepsy, as already reported for individuals with drug-resistant epilepsy, and that it could vary during treatment in those who are drug-responsive.…”

miR-17, 20a, 20b are low-expressed in A549/DDP cells and regulate cisplatin-resistant. by Zeyong Jiang (549844)

“…(<b>C</b>) Over-expression or inhibition of miR-17, 20a, 20b significantly increased or decreased the growth-inhibitory effect of cisplatin in A549/DDP cells or A549 cells. …”

Image_3_Is Gut Microbiota a Key Player in Epilepsy Onset? A Longitudinal Study in Drug-Naive Children.tif by Camilla Ceccarani (5892314)

“…In drug-naive subjects, we observed a microbial signature that shared several features with those reported in refractory epilepsy, such as an increased abundance in Akkermansia spp. and Proteobacteria and a decreased relative abundance in Faecalibacterium spp.We suggest that a bacterial-mediated proinflammatory milieu could contribute to seizure occurrence in children with new onset of epilepsy, as already reported for individuals with drug-resistant epilepsy, and that it could vary during treatment in those who are drug-responsive.…”

Injury patterns of equine-related trauma: A fifteen-year review of hospital admissions to a level 1 trauma center by Laura Cunningham (204300)

“…This study describes injury patterns in this population, to reveal potential areas for injury prevention initiatives.</p> <p>A retrospective database review of 512 non-fatal equine-related injuries over a 15-year period was conducted, using a Level 1 hospital trauma registry. …”

Table_1_A Regional View of the Response to Climate Change: A Meta-Analysis of European Benthic Organisms’ Responses.xlsx by George Hoppit (12961253)

“…European seas are transitional areas including boreal, warm-temperate, and subarctic waters with organisms frequently at limits of their distributions. Here, we use a meta-analytical approach to assess how calcification, growth, metabolism, photosynthesis, reproduction, and survival in European benthic organisms respond to ocean acidification and warming. …”

Table_1_Is Gut Microbiota a Key Player in Epilepsy Onset? A Longitudinal Study in Drug-Naive Children.docx by Camilla Ceccarani (5892314)

“…In drug-naive subjects, we observed a microbial signature that shared several features with those reported in refractory epilepsy, such as an increased abundance in Akkermansia spp. and Proteobacteria and a decreased relative abundance in Faecalibacterium spp.We suggest that a bacterial-mediated proinflammatory milieu could contribute to seizure occurrence in children with new onset of epilepsy, as already reported for individuals with drug-resistant epilepsy, and that it could vary during treatment in those who are drug-responsive.…”