HDAC2-activated gene targets. by Priyanka Somanath (4495033)

“…<p><b>(A)</b> qPCR validation of candidate targets of HDAC2 activation as determined by RNA-seq. …”

Fig 4 - by Hyun-Jun Kim (1561153)

“…<p>A) qPCR analysis of <i>Pax7</i>, <i>Myf5</i>, <i>Myod</i>, <i>Myog</i> and <i>Myh2</i> expression in differentiating C2C12 myoblasts treated with 150 nM, 300 nM or 600 nM Ni for 24 h. * = <i>p</i><0.05, ** = <i>p</i><0.01 and *** = <i>p</i><0.001 indicate significantly increased or decreased expression compared to untreated myoblasts. …”

VPS34 inhibition depletes intracellular iron by blocking iron uptake through enhanced degradation of TFR and excess iron rescues the growth defect in RKO cells. by Marek J. Kobylarz (9292599)

“…Oligomycin (Oligo) inhibits ATP synthase (Complex V) and decreases OCR; FCCP uncouples oxidative phosphorylation and increases OCR; and rotenone/antimycin A (ROT & AA) inhibits Complex I and III, respectively and decreases OCR. …”

Brassinosteroid Regulates 3‑Hydroxy-3-methylglutaryl CoA Reductase to Promote Grape Fruit Development by Ting Zheng (608653)

“…BRs can negatively regulate the expression of <i>VvHMGR</i>, a key gene involved in the mevalonate (MVA) pathway, and reduce the activity of 3-hydroxy-3-methylglutaryl CoA reductase (HMGR). …”

Hsc70-4 is required to prevent protein aggregation. by David Brooks (5369636)

“…<p>(A) Table showing prey proteins that interact with Stv in a Y2H screen. …”

Overexpression of phosphomimetic eIF4E-S209D does not affect proliferation but increases clonogenic cell survival. by Alba Martínez (732002)

“…<p>A, Western blot analysis showed similar, moderate levels of Myc-tagged exogenous eIF4E-S209D or-S209A and endogenous eIF4E expression in MDA-MB-231 and HaCaT cell lines. …”

Response to capsaicin. by Rachel Wilson (605761)

“…<p><b>Panel A</b>, Time course of Fluo-4 intensities before and after addition of Fluo-4. …”

Th17 cells provide better protection <i>in vivo</i> than Th1 cells. by Catherine W. Cai (3188976)

“…Mice were then systemically challenged with <i>T</i>. <i>cruzi</i>. (A) Parasitemia counts 19 days post-infection demonstrate that co-adoptive transfer of Th17 cells resulted in better control of infection than co-adoptive transfer of Th1 cells ***p<0.001, **p<0.01, *p<0.05 by two-tailed Student t test. …”

Brassinosteroid Regulates 3‑Hydroxy-3-methylglutaryl CoA Reductase to Promote Grape Fruit Development by Ting Zheng (608653)

“…BRs can negatively regulate the expression of <i>VvHMGR</i>, a key gene involved in the mevalonate (MVA) pathway, and reduce the activity of 3-hydroxy-3-methylglutaryl CoA reductase (HMGR). …”

Data_Sheet_1_Two novel heterozygous truncating variants in NR4A2 identified in patients with neurodevelopmental disorder and brief literature review.DOCX by Xiaozhen Song (6031166)

“…The canonical splicing variant c.1541-2A > C caused aberrant splicing, leading to the retention of intron 7 and a truncated protein due to an early termination codon within intron 7 with decreased protein expression, while the variant c.915C > A was shown to result in a shorter protein with increased expression level unexpectedly. …”

Brassinosteroid Regulates 3‑Hydroxy-3-methylglutaryl CoA Reductase to Promote Grape Fruit Development by Ting Zheng (608653)

“…BRs can negatively regulate the expression of <i>VvHMGR</i>, a key gene involved in the mevalonate (MVA) pathway, and reduce the activity of 3-hydroxy-3-methylglutaryl CoA reductase (HMGR). …”

The RTR Complex Partner RMI2 and the DNA Helicase RTEL1 Are Both Independently Involved in Preserving the Stability of 45S rDNA Repeats in <i>Arabidopsis thaliana</i> by Sarah Röhrig (3228492)

“…In plants, it consists of the RecQ helicase RECQ4A, the topoisomerase TOP3α and RMI1. Like mammals, but not yeast, plants harbor an additional complex partner, RMI2. …”

Table1_Comprehensive Analysis of N6-Methyladenosine (m6A) Methylation in Neuromyelitis Optica Spectrum Disorders.DOCX by Hong Yang (37298)

“…</p><p>Results: Compared with that in the control group, the total m6A level was decreased in the NMOSD group. Genes with upregulated methylation were primarily enriched in processes associated with RNA splicing, mRNA processing, and innate immune response, while genes with downregulated methylation were enriched in processes associated with the regulation of transcription, DNA-templating, and the positive regulation of I-kappa B kinase/NF-kappa B signalling.…”

Environmental Enrichment Reduces Anxiety by Differentially Activating Serotonergic and Neuropeptide Y (NPY)-Ergic System in Indian Field Mouse (<i>Mus booduga</i>): An Animal Model... by Durairaj Ragu Varman (746046)

“…<div><p>Exposure to a predator elicits an innate fear response and mimics several behavioral disorders related to post-traumatic stress disorder (PTSD). …”

<i>Rbfox1</i> KO animals have normal retinal morphology. by Lei Gu (422613)

“…<p>A and B. The Tg(UBC-cre/ERT2)1Ejb transgenic mouse was used to generate Rbfox1 KO animals. …”

¹H NMR-Based Metabolomics Investigation of Copper-Laden Rat: A Model of Wilson’s Disease by Jingjing Xu (418877)

“…<div><p>Background and Purpose</p><p>Wilson’s disease (WD), also known as hepatoleticular degeneration (HLD), is a rare autosomal recessive genetic disorder of copper metabolism, which causes copper to accumulate in body tissues. …”

Data_Sheet_1_GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic-Pituitary-Adrenal Axis Hyperactivity.docx by Yu Wang (12152)

“…Intriguingly, EA effectively suppressed the expression of CRH and decreased the activation of GluN2A (NMDAR subunit), ERK, and CREB in HT mice. …”

Lipocalin 2 Enhances Migration and Resistance against Cisplatin in Endometrial Carcinoma Cells - Fig 4 by Tsutomu Miyamoto (2742265)

“…<p><b>a; WST-1 assay to measure survival activity 10 hours after ultraviolet (UV) irradiation with serum starvation.…”

Table_3_A mouse model for X-linked Alport syndrome induced by Del-ATGG in the Col4a5 gene.xlsx by Wei-qing Wu (14758351)

“…The pathological changes included glomerular atrophy, increased monocytes in renal interstitial, and the absence of type IV collagen α5. The expression of Col4a5 was significantly decreased in Del-ATGG mouse model. …”

Table_2_A mouse model for X-linked Alport syndrome induced by Del-ATGG in the Col4a5 gene.xlsx by Wei-qing Wu (14758351)

“…The pathological changes included glomerular atrophy, increased monocytes in renal interstitial, and the absence of type IV collagen α5. The expression of Col4a5 was significantly decreased in Del-ATGG mouse model. …”