Data_Sheet_1_Selective stimulation of nociceptive small fibers during intraepidermal electrical stimulation: Experiment and computational analysis.pdf by Yuki Niimi (8770679)

“…Experimental results showed that perception thresholds decreased with the number of consecutive pulses and frequency up to convergence (five pulses or 70 Hz) during the selective stimulation of Aδ- and C-fibers. …”

Exposure to Bisphenol-A during Pregnancy Partially Mimics the Effects of a High-Fat Diet Altering Glucose Homeostasis and Gene Expression in Adult Male Mice by Marta García-Arevalo (5659756)

“…<div><p>Bisphenol-A (BPA) is one of the most widespread EDCs used as a base compound in the manufacture of polycarbonate plastics. …”

HIF-2α Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human Microvascular Endothelial Cells by Tessa D. Nauta (3142845)

“…In addition, hypoxia decreased the production of urokinase-type plasminogen activator (uPA), needed for migration and invasion, without a significant effect on its inhibitor PAI-1. …”

Anticardiolipin (aCL) in sera from periodontitis subjects activate Toll-like receptor 4 (TLR4) by Harvey A. Schenkein (5728673)

“…Further experiments using a human first trimester trophoblastic cell line (HTR8 sv/neo) revealed that aCL from periodontitis patients stimulated IL-8 production, which was profoundly decreased if aCL was removed by immunoabsorption or if HTR8 sv/neo were pretreated with blocking anti-TLR4 antibodies. …”

Table_1_A mouse model for X-linked Alport syndrome induced by Del-ATGG in the Col4a5 gene.xlsx by Wei-qing Wu (14758351)

“…The pathological changes included glomerular atrophy, increased monocytes in renal interstitial, and the absence of type IV collagen α5. The expression of Col4a5 was significantly decreased in Del-ATGG mouse model. …”

Video_1_Clinical Aspects of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis With Severe Ocular Complications in South Korea.MP4 by Mee Kum Kim (8452338)

“…<p>This review describes the current knowledge regarding genetic susceptibilities and treatment strategies for Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), with ocular complications, in Korea. In a case-control study, the gene frequencies of both HLA-A*0206 (20.0%) and HLA-Cw*0304 (15.0%) increased but the gene frequency of HLA-Cw*0303 (1.3%) decreased with cold medicine (CM)-SJS/TEN with severe ocular complications (SOCs). …”

Exposure to Bisphenol-A during Pregnancy Partially Mimics the Effects of a High-Fat Diet Altering Glucose Homeostasis and Gene Expression in Adult Male Mice by Marta García-Arevalo (5659756)

“…<div><p>Bisphenol-A (BPA) is one of the most widespread EDCs used as a base compound in the manufacture of polycarbonate plastics. …”

Image_2_MiR-30e-5p and MiR-15a-5p Expressions in Plasma and Urine of Type 1 Diabetic Patients With Diabetic Kidney Disease.JPEG by Cristine Dieter (6830255)

“…In this context, miR-15a-5p and miR-30e-5p have been shown to regulate the expression of the uncoupling protein 2 (UCP2), a mitochondrial protein that decreases reactive oxygen species (ROS) formation by the mitochondria. …”

Table_1_MiR-30e-5p and MiR-15a-5p Expressions in Plasma and Urine of Type 1 Diabetic Patients With Diabetic Kidney Disease.XLS by Cristine Dieter (6830255)

“…In this context, miR-15a-5p and miR-30e-5p have been shown to regulate the expression of the uncoupling protein 2 (UCP2), a mitochondrial protein that decreases reactive oxygen species (ROS) formation by the mitochondria. …”

Table_2_MiR-30e-5p and MiR-15a-5p Expressions in Plasma and Urine of Type 1 Diabetic Patients With Diabetic Kidney Disease.XLS by Cristine Dieter (6830255)

“…In this context, miR-15a-5p and miR-30e-5p have been shown to regulate the expression of the uncoupling protein 2 (UCP2), a mitochondrial protein that decreases reactive oxygen species (ROS) formation by the mitochondria. …”

Naproxen treatment also rescued defective adult neurogenesis. by Kaushik Ghosal (244754)

“…<p><b>A–B,</b> Naproxen treatment rescued decreased adult hippocampal cell proliferation in FeCγ25 mice at 3 months, quantified in <b>B</b>. …”

Tankyrase1/2 plays a role in RAD51 recruitment to DSBs and efficient HR. by Zita Nagy (273570)

“…<b>(F)</b> HR efficiency is decreasing in TNKS1/2 depleted HRind cells measured in a stable cellular system [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005791#pgen.1005791.ref049" target="_blank">49</a>]. …”

Image_1_MiR-30e-5p and MiR-15a-5p Expressions in Plasma and Urine of Type 1 Diabetic Patients With Diabetic Kidney Disease.JPEG by Cristine Dieter (6830255)

“…In this context, miR-15a-5p and miR-30e-5p have been shown to regulate the expression of the uncoupling protein 2 (UCP2), a mitochondrial protein that decreases reactive oxygen species (ROS) formation by the mitochondria. …”

Image_2_GHS-R1a Deficiency Alleviates Depression-Related Behaviors After Chronic Social Defeat Stress.JPEG by Li Guo (171454)

“…Ghrelin functions by binding to its receptor, the growth hormone secretagogue receptor 1a (GHS-R1a), which is widely expressed inside and outside of the brain. …”

End Stage Renal Disease Predicts Increased Risk of Death in First Degree Relatives in the Norwegian Population by Rannveig Skrunes (3339708)

“…Excluding known hereditary renal disease, aHR decreased to 1.12 (1.09–1.15). Cardiovascular death aHR was 1.15 (1.10–1.21), of which cerebrovascular death 1.34 (1.22–1.50). aHR for death due to non-hereditary renal/ureteric disease was 2.29 (1.81–2.91) with renal failure 1.80 (1.26–2.56) and glomerular disease 5.69 (3.88–8.34) as main contributors. …”

MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of <i>Mycobacterium tuberculosis</i> to lysosomes... by Sanjaya Kumar Sahu (4054438)

“…Here we report for the first time, that the transcription factor KLF4 is targeted by microRNA-26a (miR-26a). During Mtb infection, downregulation of miR-26a (observed both <i>ex vivo</i> and <i>in vivo</i>) facilitates upregulation of KLF4 which in turn favors increased arginase and decreased iNOS activity. …”

DataSheet_1_The cytoplasmic LSm1-7 and nuclear LSm2-8 complexes exert opposite effects on Hepatitis B virus biosynthesis and interferon responses.docx by Naimur Rahman (13220196)

“…Specifically, in G2/M phase, IFN-α increased protein level of LSm1, the unique subunit of cytoplasmic LSm1-7 complex involved in mRNA decay. By contrast, IFN-α decreased LSm8, the unique subunit of nuclear LSm2-8 complex, a chaperone of U6 spliceosomal RNA, suggesting the cytoplasmic LSm1-7 complex is antiviral, whereas the nuclear LSm2-8 complex is pro-viral. …”

Image_1_GHS-R1a Deficiency Alleviates Depression-Related Behaviors After Chronic Social Defeat Stress.JPEG by Li Guo (171454)

“…Ghrelin functions by binding to its receptor, the growth hormone secretagogue receptor 1a (GHS-R1a), which is widely expressed inside and outside of the brain. …”

Image_10_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.t... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_2_Monoallelic Heb/Tcf12 Deletion Reduces the Requirement for NOTCH1 Hyperactivation in T-Cell Acute Lymphoblastic Leukemia.jpeg by Diogo F. T. Veiga (12282320)

“…At the molecular level, HEB protein levels are decreased via proteasomal degradation at the leukemic stage, pointing to a reversible loss of function mechanism. …”