Deletion of SIRT1 in osteoclasts or osteoblasts results in a low bone mass phenotype. by Kayvan Zainabadi (502381)

“…<p>(A) Osteoclast tissue specific SIRT1 knockout mice (OcKO) show excision of SIRT1 in osteoclasts, but not liver, as indicated by a smaller PCR product obtained with primers flanking SIRT1 catalytic exon 4 (T1Δ4). …”

Table_1_BNP as a New Biomarker of Cardiac Thyroid Hormone Function.DOCX by Kaihao Wang (9100646)

“…The objective of this study was to investigate BNP as a potential serum biomarker for TH function in the heart.…”

HPLC analysis of <i>M. tuberculosis</i> ThyA and ThyX products. by Joshua H. Hunter (47803)

“…Based on absorbance at 260 nm, the peak corresponding to dUMP (t_r = 8.8 min) decreases while the peak corresponding to TMP (t_r = 11.1 min) increases over a 120 minute time course (0, 30, 60, and 120 minute time points). …”

Treatment with IBMX has different effects on hippocampal neurons and striatal neurons (A–C). by Sigeng Chen (248428)

“…<p>A. Inhibition of mitochondrial movement by IBMX. …”

DsRed fluorescence following a heat-shock in <i>Drosophila</i> pupae. by Bin Chen (63682)

“…<p>Heat-shocks lead either to increased (A) or decreased (B) DsRed protein levels. Pupal phenotypes of wild-type, over-expression (<i>Pogostick-up-1</i>), and down-regulation (resulting from a cross between <i>pBac[3×P3−DsRedaf]</i> and <i>Pogostick-down-RF</i> homozygous parents) lines targeting the <i>DsRed</i> gene in transgenic <i>Drosophila</i>, before and after a heat-shock (HS). …”

Antioxidant Carbocysteine Treatment in Obstructive Sleep Apnea Syndrome: A Randomized Clinical Trial by Kang Wu (160544)

“…The CPAP group also showed a decreased oxygen desaturation index and a significant increase in the mean oxygen saturation after treatment, but these increases were not observed in the carbocysteine group. …”

Impact of acute undernutrition on growth, ileal morphology and nutrient transport in a murine model by I.C. Sampaio (6511346)

“…<div><p>Undernutrition represents a major public health challenge for middle- and low-income countries. …”

Influence of Solubilizing Group Removal Rate on the Morphology and Crystallinity of a Diketopyrrolopyrrole-Based Compound by Shabi Thankaraj Salammal (1864396)

“…The increment in intermolecular N–H···OC hydrogen bond length together with the trapped gaseous byproducts results in a blue shift in the UV–vis absorption spectra while decreasing the heating rate as well as the isothermal decarboxylation temperature.…”

Methyl Farnesoate Plays a Dual Role in Regulating <i>Drosophila</i> Metamorphosis by Di Wen (313779)

“…Reducing <i>hmgcr</i> expression in the CA of the <i>jhamt</i> mutant further decreased MF titer to a very low level, and caused complete lethality. …”

Influence of Solubilizing Group Removal Rate on the Morphology and Crystallinity of a Diketopyrrolopyrrole-Based Compound by Shabi Thankaraj Salammal (1864396)

“…The increment in intermolecular N–H···OC hydrogen bond length together with the trapped gaseous byproducts results in a blue shift in the UV–vis absorption spectra while decreasing the heating rate as well as the isothermal decarboxylation temperature.…”

Microscope findings of liver (A; H&E, ×200) and hepatitis activity garde (B). by Meegun Hong (693378)

SHAP Tree explainer for (a) Model 1: Presentation and (b) Model 6: Closures. by Nathan C. Hurley (10510304)

“…For instance, on the top row of <a href="/article/info:doi/10.1371/journal.pdig.0000906#pdig.0000906.g002" target="_blank">Fig 2</a>, a preprocedural hemoglobin greater than 13 is associated with an increased risk of bleeding, while value less than 13 is associated with a decreased risk. …”

Aqueous humor VEGF-A concentration in the pre-IVR and post-IVR NVG eyes. by Minwen Zhou (452903)

“…<p>Compared to pre-IVR, the mean aqueous humor VEGF-A concentration significantly decreased post-IVR in the NVG eyes (*p<0.001). …”

A three-state prediction of single point mutations on protein stability changes-2 by Emidio Capriotti (9889)

“…Rate (TPR) versus the False Positive Rate (FPR) are plotted the best method (SVM-WIN31) and for the baseline method (SVM-BASE). In part (A) the ROC curves of the two methods are relative to the prediction of increasing and decreasing free energy mutations (…”

Magnitude of mean change in SE across groups in the A contrast and B orientation task. by George Zacharopoulos (5660800)

Comparison of conventional streamline rendering (a) with local orientation-dependent transparency rendering (b). by Chantal M. W. Tax (606885)

Effect of welding gap on electromagnetic pulse welding of a copper-aluminum alloy joint by Yan Zhou (6523)

“…During the EMPW experiments, the deformation, collision, and metal jet were recorded with a high-speed camera. The joint mechanical property was tested. …”

Correlation between NAD⁺ levels and Age in (A) Males (B) Females. by Hassina Massudi (313890)

“…</b> NAD⁺ levels decreased significantly in males aged between 0–77 years (line a; p = 0.0007; n = 27). …”

Heme Mediates Cytotoxicity from Artemisinin and Serves as a General Anti-Proliferation Target by Shiming Zhang (259018)

“…A natural products library was screened which identified the compound coralyne, in addition to artemisinin, as a heme interacting compound with heme synthesis dependent cytotoxic activity. …”

Global smoking trends in inflammatory bowel disease: A systematic review of inception cohorts by Tom Thomas (3565337)

“…Smoking prevalence trends specific to the global IBD cohort over time have not been previously reported. This is a systematic review of smoking prevalence specific to the IBD cohort across geography.…”