D3DistalMutation: a Database to Explore the Effect of Distal Mutations on Enzyme Activity by Xiaoyu Wang (182979)

“…As a result, we observed that approximately 80% of distal mutations could affect enzyme activity and 72.7% of distal mutations would decrease or abolish enzyme activity in D3DistalMutation. …”

DCA promotes a shift from aerobic glycolysis to oxidative phosphorylation in flies surviving sepsis. by Veli Bakalov (3481280)

“…When flies were fed DCA, infection effect was partially reversed with a decrease in lactate among sepsis survivors returning to levels similar to that in the sham group. …”

Incidence and survival of laryngeal cancer in Denmark: a nation-wide study from 1980 to 2014 by Arvin Nahavandipour (6415004)

“…</p> <p><b>Conclusions:</b> This nation-wide study reports a significant decrease in the incidence of laryngeal cancer. …”

A Combined Metabonomic and Transcriptomic Approach to Investigate Metabolism during Development in the Chick Chorioallantoic Membrane by Rachel Cavill (225747)

“…The time courses common to the metabolite clusters distinguished specific stages of vessel growth, identifying waste product metabolites being stored in the CAM and energy-related substrates decreasing during embryonic growth. Using this top-down approach, combined with existing microarray data, we could link gene expression to metabolic consequences during the growth of a vascularized organ. …”

The expression of pain receptors in <i>α</i>-GalA KO males frontal paws. by Jarmila Lakomá (152379)

“…The analysis of TRPM8 (Santa Cruz) expression (∼127 kDa) in the whole protein extract from skin of frontal paws showed the almost half expression decrease in protein expression of TRPM8 in case of α-GalA KO (n = 3) males when compared to WT (n = 3), p = 0.0518. …”

Evaluation of Progressive Retinal Degeneration in Bipolar Disorder Patients over a Period of 5 Years by Maria Satue (3095016)

“…</p> <p>Visual function parameters in BD patients remained unchanged during the follow-up period. A progressive decrease affecting macular and peripapillary RNFL thickness (<i>p</i> < 0.050) was observed in patients. …”

Preliminary molecular characterization of a proinflammatory and nociceptive molecule from the Echinometra lucunter spines extracts by Juliana Mozer Sciani (4626790)

“…Spines were removed and molecules were extracted, fractionated by RP-HPLC and assayed for inflammatory and nociceptive activity, in a biological-driven fractionation way, until the obtainment of one active molecule and its subsequent analysis by mass spectrometry (MS and MS/MS). …”

Supplementary Material for: Effects of exercise during chemo- or radiotherapy on immune markers – a systematic review by DeHoop A.M.S. (17085538)

“…The majority of markers was unaltered, but observed effects included a suppressive effect of exercise during radiotherapy on some pro-inflammatory markers, a preserving effect of exercise during chemotherapy on NK cell degranulation and cytotoxicity, a protective effect on the decrease in thrombocytes during chemotherapy, and a positive effect of exercise during chemotherapy on IgA. …”

The impact of the COVID-19 pandemic on dental trauma attendance: a systematic review and meta-analysis by Débora e Silva CAMPOS (14524435)

“…Meta-analysis was performed in RevMan 5.4 software with Odds Ratios as a pooled measure of effect, with a 95% confidence interval, and using random-effects modeling. …”

A novel method for flap delay vacuum assisted flap delay: an experimental study in rabbits by Osman Enver Aydin (6530654)

“…The golden standard method of delay is a surgical delay. On the other hand, a major drawback of surgical delay is two sessions of surgery. …”

Supplementary Material for: Effects of exercise during chemo- or radiotherapy on immune markers – a systematic review by DeHoop A.M.S. (17085538)

“…The majority of markers was unaltered, but observed effects included a suppressive effect of exercise during radiotherapy on some pro-inflammatory markers, a preserving effect of exercise during chemotherapy on NK cell degranulation and cytotoxicity, a protective effect on the decrease in thrombocytes during chemotherapy, and a positive effect of exercise during chemotherapy on IgA. …”

αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor by Fanny Kortüm (770280)

“…Through interaction αPIX sequesters c-Cbl from EGFR and this results in reduced EGFR ubiquitination and decreased EGFR degradation upon EGF treatment. However, quantitatively more decisive for cellular EGFR distribution than impaired EGFR degradation is a strong stimulating effect of αPIX on EGFR recycling to the cell surface. …”

The coexistence of traditional medicine and biomedicine: A study with local health experts in two Brazilian regions by Sofia Zank (3929357)

“…In the maroon communities, a greater number of specialists thought there was a decrease in the number and demand for healers, as well as the use of medicinal plants, due to changes in traditional livelihoods, since they are located in a region where the effects of the modernization were more intense. …”

A General Strategy for Biocompatible, High-Effective Upconversion Nanocapsules Based on Triplet–Triplet Annihilation by Qian Liu (135614)

“…A general strategy for constructing high-effective upconversion nanocapsules based on triplet–triplet annihilation (TTA) was developed by loading both sensitizer and annihilator into BSA–dextran stabilized oil droplets. …”

Table1_Thyroid dysfunction and sarcopenia: a two-sample Mendelian randomization study.docx by Jiaxin Wei (12019231)

“…</p>Results<p>The MR analysis indicated that hyperthyroidism could lead to a significant decrease in ALM in the extremities (OR = 1.03; 95% CI = 1.02 to 1.05; P < 0.001). …”

DataSheet1_A Zebrafish Model of Neurotoxicity by Binge-Like Methamphetamine Exposure.PDF by Juliette Bedrossiantz (11736794)

“…After an initial testing at 20 and 40 mg/L for 48 h, the later METH concentration was selected for developing the model and the effects on the brain monoaminergic profile, locomotor, anxiety-like and social behaviors as well as on the expression of key genes of the catecholaminergic system were determined. A concentration- and time-dependent decrease in the brain levels of dopamine (DA), norepinephrine (NE) and serotonin (5-HT) was found in METH-exposed fish. …”

Comprehensive Analysis of the Naturally Processed Peptide Repertoire: Differences between HLA-A and B in the Immunopeptidome by Ingrid M. M. Schellens (377152)

“…After viral infection, the number of unique self-peptides eluted significantly decreased compared to uninfected cells, paralleled by a decrease in the number of source proteins. …”

Doses of enzyme complex in a high-energy diet on performance and carcass traits of feedlot steers by Gabriela Letícia Delai Vigne (6015992)

“…Each gram of product added to the diet led to a decrease of 0.0818 kg in daily dry matter intake (DMI), whereas fat thickness at the ribs and at the hindquarter increased by 0.3850 and 0.080 mm, respectively. …”

Image_1_Transmembrane Peptides as a New Strategy to Inhibit Neuraminidase-1 Activation.jpg by Camille Albrecht (9774560)

“…Accumulative data have shown that inhibition of neuraminidases, such as NEU1 sialidase, may be a promising pharmacological target, and selective inhibitors of NEU1 are therefore needed to better understand the biological functions of this sialidase. …”

Synthesis and Preclinical Validation of Novel Indole Derivatives as a GPR17 Agonist for Glioblastoma Treatment by Phung Nguyen (230474)

“…The <b>CHBC</b>–GPR17 interaction leads to a rapid decrease of cAMP and Ca²⁺. <b>CHBC</b> exhibits the cytotoxicity effect on GBM cells in a dose-dependent manner with an IC₅₀ of 85 μM, whereas the known agonist MDL29,951 showed a negligible effect. …”