Expression of a Constitutively Active Calcineurin Encoded by an Intron-Retaining mRNA in Follicular Keratinocytes by Atsushi Fujimura (227683)

“…Overexpression of cyclin G2 arrested the cell cycle in follicular keratinocytes <em>in vitro</em> and the Cn inhibitor, cyclosporin A, inhibited nuclear localization of NFATc2, resulting in decreased cyclin G2 expression in follicular keratinocytes of rats <em>in vivo</em>. …”

Table_7_Effects of Taurine on Primary Metabolism and Transcription in a Coral Symbiodinium sp..xlsx by Aiyou Huang (404014)

“…The results revealed that taurine significantly increased the growth, photosynthesis efficiency, total soluble sugar, chlorophyll a, and chlorophyll b and free amino acid content of Symbiodinium sp. while decreased the content of total insoluble sugar. …”

Table_3_A Role for PICKLE in the Regulation of Cold and Salt Stress Tolerance in Arabidopsis.xlsx by Rong Yang (107028)

“…<p>Arabidopsis PICKLE (PKL) is a putative CHD3-type chromatin remodeling factor with important roles in regulating plant growth and development as well as RNA-directed DNA methylation (RdDM). …”

Image_5_Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus.PDF by Sebastian Reichert (553783)

“…<p>In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. …”

Image_2_Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus.PDF by Sebastian Reichert (553783)

“…<p>In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. …”

Supplementary Material for: Continuous Intragastric Dextrose: A Therapeutic Option for Refractory Hypoglycemia in Congenital Hyperinsulinism by Vajravelu M.E. (5607443)

“…<b><i>Methods:</i></b> This was a retrospective cohort of infants with HI treated with IGD from 2009–2017. …”

Data_Sheet_1_The Aha! experience is associated with a drop in the perceived difficulty of the problem.docx by Nadezhda V. Moroshkina (12904751)

“…Our findings revealed that the initial ratings of the problem’s subjective difficulty were positively correlated with the solution time and that this correlation decreased in the case of a stronger Aha! experience. …”

A Pathogenic Mechanism in Huntington's Disease Involves Small CAG-Repeated RNAs with Neurotoxic Activity by Mónica Bañez-Coronel (181601)

“…These results suggest a possible link between HD and sCAG expression with an aberrant activation of the siRNA/miRNA gene silencing machinery, which may trigger a detrimental response. …”

IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models by Anjelika Gasilina (8566296)

“…<div><p>We report the synthesis and preliminary characterization of IODVA1, a potent small molecule that is active in xenograft mouse models of Ras-driven lung and breast cancers. …”

Use of Thiopurines and Risk of Colorectal Neoplasia in Patients with Inflammatory Bowel Diseases: A Meta-Analysis by Jianfeng Gong (177593)

“…The use of thiopurines was associated with a statistically significant decreased incidence of colorectal neoplasm (summary RR=0.71, 95% CI=0.54–0.94, p=0.017), even after adjustment for duration and extent of the disease, but there was high heterogeneity among studies (<i>I</i>²=68.0%, p<0.001). …”

Clinical value of thalidomide on kk-rat model through TNF-a mediated inflammation approach by Min HUANG (12728997)

“…The levels of TNF-α, IL-1β, interleukin -6 (IL-6) and interleukin -18 (IL-18) of kk-Ay in the thalidomide group and the model control group were both at a higher level before treatment, but the difference was not statistically significant (P >0.05); The levels of TNF-α, IL-1β, interleukin -6 (IL-6) and interleukin -18 (IL-18) in kk-Ay rats 8/10/12 weeks after the treatment in the thalidomide group were significantly decreased, with statistically significant differences compared with the model control group (P < 0.05). …”

Table_2_Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus.DOCX by Sebastian Reichert (553783)

“…<p>In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. …”

Supplementary Material for: Long-Term Outcomes of Developmental Exposure to Fluoxetine: A Review of the Animal Literature by Kiryanova V. (4142347)

“…An estimated 1.4-2.1% of pregnant women use this medication, which inhibits the reuptake of serotonin and thereby increases serotonergic activity at the synapse. Serotonin acts as a cue guiding numerous neurodevelopmental processes, and changes in the concentration of serotonin can disrupt normal in utero brain development and organization in humans and other animals, thus providing a mechanism by which maternal intake of FLX might alter neural development and ultimately behaviour. …”

Recreational Use of the Countryside: No Evidence that High Nature Value Enhances a Key Ecosystem Service by Karen Hornigold (3339594)

“…Models were based on a massive, three year national household survey providing spatially-referenced recreational visits to the natural environment. …”

Establishment of a yeast essential protein conditional-degradation library and screening for autophagy-regulating genes by Yi Zhang (9093)

“…In summary, the yeast essential protein conditional degradation library we constructed will serve as a valuable resource for systematically investigating the roles of essential genes in autophagy and other biological functions.…”

<i>NEXN</i> Is a Novel Susceptibility Gene for Coronary Artery Disease in Han Chinese by Chong Wu (130393)

“…Further eQTL analysis demonstrated that the risk allele T of rs1780050 is associated with decreased expression of NEXN, thus contributing to a higher risk of CAD susceptibility in the population. …”

Mesomorphic properties of cyanobiphenyl dimers with a substituted central malonate unit: overruling effect of fluorination by Marco André Grunwald (5425064)

“…In case of C2-hexyl-substituted dimers, shorter spacers favoured N phases (n = 6–9), while longer spacers favoured SmA phases (n ≥ 9). In addition, decreased clearing temperatures were observed. …”

Failure of Passive Immune Transfer in Calves: A Meta-Analysis on the Consequences and Assessment of the Economic Impact by Didier Raboisson (2833616)

“…Neither a quantitative analysis of FPT consequences nor an assessment of its total cost are available. …”

Table_2_Oxytocin predicts positive affect gains in a role-play interaction.docx by Alexandru I. Berceanu (9241328)

“…</p>Results<p>In our experiment, role-play significantly increased positive affect and prosocial attitudes and decreased anxiety compared to a control condition. …”

<i>her8a</i> is regulated by the Su(H)-dependent Notch signaling pathway. by Pei-Chen Chung (223912)

“…(I) The levels of <i>her8a</i> expression in <i>Su(H)</i> variant injected embryos were further quantified by qPCR, showing significantly increased <i>her8a</i> expression in <i>ANK</i> injected embryos and decreased expression in <i>DBM</i> over-expressed embryos. …”