Choroidal structure as a biomarker for visual acuity in intravitreal aflibercept therapy for polypoidal choroidal vasculopathy by Shotaro Asano (5204663)

“…</p><p>Methods</p><p>We conducted a retrospective, single-centre and observational study including 18 eyes of 18 patients with PCV (73.8 ± 10.2 years of age) who were treated with three monthly intravitreal aflibercept injections followed by additional treatments in a treat-and-extend protocol. …”

Unravelling the regulation mechanism in a synthetic gene network integrated in human kidney cells [82]. by Feng Jiao (390944)

“…<p><b>A</b>: In the network, a bidirectional promoter transcribes the zsGreen-LacI and dsRed transcripts. …”

A Biomimetic Interface with High Adhesion, Tailorable Modulus for On-Skin Sensors, and Low-Power Actuators by Song Chen (69646)

“…In addition to the adhesion function, the interface can also help lock the actuator states thanks to the tunable modulus of the interface, which is highly valuable for decreasing the power consumption of the actuator. This work provides a new avenue to address both sensing and actuating bottlenecks by focusing on the interface.…”

The Selective SGLT2 Inhibitor Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepatitis in Mice by Yasushi Honda (679225)

“…<div><p>Background & Aims</p><p>In recent years, nonalcoholic steatohepatitis (NASH) has become a considerable healthcare burden worldwide. Pathogenesis of NASH is associated with type 2 diabetes mellitus (T2DM) and insulin resistance. …”

Easy-to-Use Osmosis-Based Microfluidic Chip for Protein Crystallization: Application to a Monoclonal Antibody by Sandy Morais (10723660)

“…The water chemical activity fixed by the reservoir makes it possible to modify the volume of the droplets in a controlled way (reduction or increase). Because PDMS is only permeable to water, the imposed water activity therefore increases or decreases the concentration of the solutes present in the droplet and consequently the supersaturation of the solution. …”

Osmotically Rupturing Phagosomes in Macrophages Using PNIPAM Microparticles by Wenhao Cheng (6741377)

“…The rupture of macrophage phagosomes has been implicated in various human diseases and plays a critical role in immunity. However, the mechanisms underlying this process are complex and not yet fully understood. …”

Number of fish tagged by treatment and date. by April S. Cameron (8622711)

“…For all study fish, the presence of two intact sutures seven days post-surgery (generally associated with good suturing technique) was negatively correlated with survival. A generalized linear mixed effects model indicated that suture presence, increasing tagging temperature, and the presence of foreign material on sutures decreased survival by 0.56, 0.72 and 0.60 respectively. …”

Shortest-Path Network Analysis Is a Useful Approach toward Identifying Genetic Determinants of Longevity by J. R. Managbanag (269125)

“…Here we report that the single-gene deletion strains identified by our shortest-path longevity analysis are significantly enriched for mutations conferring either increased or decreased replicative life span, relative to a randomly selected set of 564 single-gene deletion strains or to the current data set available for the entire haploid deletion collection. …”

The Association between Malaria and Iron Status or Supplementation in Pregnancy: A Systematic Review and Meta-Analysis by Laura Sangaré (251012)

“…Iron deficiency was associated with a decreased malaria risk in pregnancy only when measured with ferritin. …”

Data_Sheet_1_Microbial Community Response to a Novel Salmon Resource Subsidy.PDF by Courtney E. Larson (8278182)

“…<p>Salmon decomposition is traditionally viewed through the lens of energy and nutrient subsidies, but not as a potential “microbial subsidy.” Microbial communities residing on and within spawning salmon are directly introduced into streams after host death. …”

Image_2_TNAP—a potential cytokine in the cerebral inflammation in spastic cerebral palsy.TIF by Xiao-Kun Wang (5745635)

“…In contrast, compared with the sham rats, the model rats demonstrated a significant increase in osteopontin and proinflammatory biomarkers in both the plasma and cerebral cortex on the ischemic side whereas serum 25 hydroxyvitamin D and IL-10 were significantly decreased. …”

Image_1_TNAP—a potential cytokine in the cerebral inflammation in spastic cerebral palsy.TIF by Xiao-Kun Wang (5745635)

“…In contrast, compared with the sham rats, the model rats demonstrated a significant increase in osteopontin and proinflammatory biomarkers in both the plasma and cerebral cortex on the ischemic side whereas serum 25 hydroxyvitamin D and IL-10 were significantly decreased. …”

Table_1_Causal association of circulating cytokines with sepsis: a Mendelian randomization study.xlsx by Shan Lin (228596)

“…</p>Methods<p>We performed a two-sample MR analysis to investigate this causality relationship in individuals of European ancestry. …”

Evaluation of the Association between the AC3 Genetic Polymorphisms and Obesity in a Chinese Han Population by Hairu Wang (238131)

“…</p><h3>Conclusions</h3><p>The present study provides replication evidence that the AC3 genetic polymorphisms are associated with decreased risk of obesity among adults but not in children in a Chinese Han population. …”

Ginkgo Biloba Extract Ameliorates Oxidative Phosphorylation Performance and Rescues Aβ-Induced Failure by Virginie Rhein (243241)

“…In APP cells, the GBE-induced amelioration of oxygen consumption most likely arose from the modulation and respective normalization of the Aβ-induced disturbance in the activity of mitochondrial complexes III and IV restoring impaired ATP levels possibly through decreasing Aβ and oxidative stress level.…”

Anaemia and mortality in patients with transcatheter aortic valve replacement: a systematic review and meta-analysis by Napatt Kanjanahattakij (5484059)

“…</p> <p><b>Introduction:</b> TAVR is now a treatment option for patients with severe aortic stenosis (AS) with high surgical risk. …”

Image_5_Causal association of circulating cytokines with sepsis: a Mendelian randomization study.tiff by Shan Lin (228596)

“…</p>Methods<p>We performed a two-sample MR analysis to investigate this causality relationship in individuals of European ancestry. …”

SEMA6A is expressed in neural crest cells that give rise to boundary cap cells by Olivier Mauti (40551)

“…After HH30, SEMA6A expression in dorsal (open arrowhead in (n)) and ventral (arrowhead in (n)) BCCs decreased but was still visible by HH36 (o). hybridizations on adjacent transverse sections of the lumbosacral spinal cord are shown for SEMA6A (a, e, i, m-p), KROX20 (b, f, j), and SOX10 (c, g, k) at HH19 (a-d), HH21 (e-h), HH24 (i-l) as indicated. …”

Type A PCs auto-synchronize via MC^α2 inhibition. by Markus M. Hilscher (473981)

“…<p>(A) Coupling one PC (black) out of two unconnected type A PCs to the light source/optical feedback inhibition system shows unsynchronized activity before and synchronized APs during optical feedback inhibition. …”

Sulfate Reduction Drives Elevated Methylmercury Formation in the Water Column of a Eutrophic Freshwater Lake by Benjamin D. Peterson (9678659)

“…In this study, both Hg methylation and MeHg demethylation in a eutrophic freshwater lake were linked to ambient MeHg concentrations and <i>hgcA</i> abundance and expression. …”