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48421
Image_5_Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus.PDF
Published 2018“…<p>In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. …”
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48422
Image_2_Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus.PDF
Published 2018“…<p>In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. …”
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48423
Supplementary Material for: Continuous Intragastric Dextrose: A Therapeutic Option for Refractory Hypoglycemia in Congenital Hyperinsulinism
Published 2018“…<b><i>Methods:</i></b> This was a retrospective cohort of infants with HI treated with IGD from 2009–2017. …”
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48424
Data_Sheet_1_The Aha! experience is associated with a drop in the perceived difficulty of the problem.docx
Published 2024“…Our findings revealed that the initial ratings of the problem’s subjective difficulty were positively correlated with the solution time and that this correlation decreased in the case of a stronger Aha! experience. …”
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48425
A Pathogenic Mechanism in Huntington's Disease Involves Small CAG-Repeated RNAs with Neurotoxic Activity
Published 2012“…These results suggest a possible link between HD and sCAG expression with an aberrant activation of the siRNA/miRNA gene silencing machinery, which may trigger a detrimental response. …”
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48426
IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models
Published 2020“…<div><p>We report the synthesis and preliminary characterization of IODVA1, a potent small molecule that is active in xenograft mouse models of Ras-driven lung and breast cancers. …”
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48427
Use of Thiopurines and Risk of Colorectal Neoplasia in Patients with Inflammatory Bowel Diseases: A Meta-Analysis
Published 2013“…The use of thiopurines was associated with a statistically significant decreased incidence of colorectal neoplasm (summary RR=0.71, 95% CI=0.54–0.94, p=0.017), even after adjustment for duration and extent of the disease, but there was high heterogeneity among studies (<i>I</i><sup>2</sup>=68.0%, p<0.001). …”
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48428
Clinical value of thalidomide on kk-rat model through TNF-a mediated inflammation approach
Published 2022“…The levels of TNF-α, IL-1β, interleukin -6 (IL-6) and interleukin -18 (IL-18) of kk-Ay in the thalidomide group and the model control group were both at a higher level before treatment, but the difference was not statistically significant (P >0.05); The levels of TNF-α, IL-1β, interleukin -6 (IL-6) and interleukin -18 (IL-18) in kk-Ay rats 8/10/12 weeks after the treatment in the thalidomide group were significantly decreased, with statistically significant differences compared with the model control group (P < 0.05). …”
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48429
Table_2_Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus.DOCX
Published 2018“…<p>In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. …”
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48430
Supplementary Material for: Long-Term Outcomes of Developmental Exposure to Fluoxetine: A Review of the Animal Literature
Published 2013“…An estimated 1.4-2.1% of pregnant women use this medication, which inhibits the reuptake of serotonin and thereby increases serotonergic activity at the synapse. Serotonin acts as a cue guiding numerous neurodevelopmental processes, and changes in the concentration of serotonin can disrupt normal in utero brain development and organization in humans and other animals, thus providing a mechanism by which maternal intake of FLX might alter neural development and ultimately behaviour. …”
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48431
Recreational Use of the Countryside: No Evidence that High Nature Value Enhances a Key Ecosystem Service
Published 2016“…Models were based on a massive, three year national household survey providing spatially-referenced recreational visits to the natural environment. …”
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48432
Establishment of a yeast essential protein conditional-degradation library and screening for autophagy-regulating genes
Published 2025“…In summary, the yeast essential protein conditional degradation library we constructed will serve as a valuable resource for systematically investigating the roles of essential genes in autophagy and other biological functions.…”
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48433
<i>NEXN</i> Is a Novel Susceptibility Gene for Coronary Artery Disease in Han Chinese
Published 2013“…Further eQTL analysis demonstrated that the risk allele T of rs1780050 is associated with decreased expression of NEXN, thus contributing to a higher risk of CAD susceptibility in the population. …”
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48434
Mesomorphic properties of cyanobiphenyl dimers with a substituted central malonate unit: overruling effect of fluorination
Published 2022“…In case of C2-hexyl-substituted dimers, shorter spacers favoured N phases (n = 6–9), while longer spacers favoured SmA phases (n ≥ 9). In addition, decreased clearing temperatures were observed. …”
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48435
Failure of Passive Immune Transfer in Calves: A Meta-Analysis on the Consequences and Assessment of the Economic Impact
Published 2016“…Neither a quantitative analysis of FPT consequences nor an assessment of its total cost are available. …”
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48436
Table_2_Oxytocin predicts positive affect gains in a role-play interaction.docx
Published 2024“…</p>Results<p>In our experiment, role-play significantly increased positive affect and prosocial attitudes and decreased anxiety compared to a control condition. …”
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48437
<i>her8a</i> is regulated by the Su(H)-dependent Notch signaling pathway.
Published 2011“…(I) The levels of <i>her8a</i> expression in <i>Su(H)</i> variant injected embryos were further quantified by qPCR, showing significantly increased <i>her8a</i> expression in <i>ANK</i> injected embryos and decreased expression in <i>DBM</i> over-expressed embryos. …”
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48438
Supplementary Material for: Dementia with grains, a clinical mimic of dementia with Lewy bodies - Case Report
Published 2025“…These symptoms in combination with decreased striatal uptake of tracer on a 123I-FP-CIT-SPECT scan led to the clinical diagnosis of probable mild dementia with Lewy bodies. …”
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48439
Prevalence of xerostomia and its association with systemic diseases and medications in the elderly: a cross-sectional study
Published 2022“…Its origins are multicausal and might be the result of a change in the salivary glands or a systemic imbalance. …”
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48440
Effect of acetylcholinesterase inhibitors on post-stroke cognitive impairment and vascular dementia: A meta-analysis
Published 2020“…<div><p>Cognitive impairment is a common complication observed after a stroke. …”