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48761
Biological effects of ultrashort electric pulses in a neuroblastoma cell line: the energy density role
Published 2021“…<p>Despite the numerous literature results about biological effects of electromagnetic field (EMF) exposure, the interaction mechanisms of these fields with organisms are still a matter of debate. Extremely low frequency (ELF) MFs can modulate redox homeostasis and we showed that 24 h exposure to 50 Hz–1 mT has a pro-oxidant effect and effects on the epigenome of SH-SY5Y cells, decreasing miR-34b/c expression through the hypermethylation of their promoter.…”
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48762
Image1_Exploring Ecoacoustic Trajectories in a Giant Sequoia Forest After Wildfire.JPEG
Published 2022“…<p>Forest management strategies that create spatially diverse fire-caused disturbance outcomes, consistent with historic fire regimes, are a desired condition for fire adapted western United States forests. …”
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48763
Identification of CDK6 as a NF-κB p65 Ser536 kinase.
Published 2013“…Proteins were eluted from phenyl sepharose with a decreasing salt gradient (1 M to 0 M) and individual fractions assayed for <i>in vitro</i> phosphorylation of Ser536 using GST-p65<sub>354- 551</sub> as substrate. …”
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48764
Use of a Novel Chagas Urine Nanoparticle Test (Chunap) for Diagnosis of Congenital Chagas Disease
Published 2014“…The nanoparticles concentrate <i>T. cruzi</i> antigens by 100 fold (western blot detection limit decreased from 50 ng/ml to 0.5 ng/ml). The sensitivity of Chunap in a single specimen at one month of age was 91.3% (21/23, 95% CI: 71.92%–98.68%), comparable to PCR in two specimens at 0 and 1 month (91.3%) and significantly higher than microscopy in two specimens (34.8%, 95% CI: 16.42%–57.26%). …”
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48765
Actomyosin network R<sub>g,f</sub>/R<sub>g,i</sub> over time for various R<sub>α:a</sub> with fixed R<sub>m:a</sub> = 0.01.
Published 2016“…<p>We see that above a threshold <i>α</i>-actinin concentration, contraction is observed, and the time of bundle formation for these contractile structure formations decreases with increasing <i>α</i>-actinin concentration. …”
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48766
THE ROLE OF QATAR COMMUNITY PHARMACISTS IN DEPRESSION CARE: A SURVEY OF ATTITUDES, PRACTICES AND PERCEIVED BARRIERS
Published 2020“…Depression practice score increased with an increasing score of attitudes (p =0.001), and decreased with the number of years since the last pharmacy degree graduation (p=0.02).The presence of a private area for counselling patients was associated with higher scores of practice (p=0.03). …”
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48767
Short Daily versus Conventional Hemodialysis for Hypertensive Patients: A Randomized Cross-Over Study
Published 2014“…</p><p>Study Design, Setting and Participants</p><p>We undertook a randomized cross-over trial in adult hypertensive patients with ESRD treated with conventional hemodialysis to determine: 1) if short-daily hemodialysis is associated with a reduction in systolic blood pressure after a 3-month blood pressure optimization period and; 2) the potential mechanism(s) of blood pressure reduction. …”
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48768
pH-Lemon, a Fluorescent Protein-Based pH Reporter for Acidic Compartments
Published 2019“…Fusion of pH-Lemon to the protein microtubule-associated protein 1A/1B-light chain 3B (LC3B), a specific marker of autophagic membranes, resulted in its targeting within autolysosomes of HeLa cells. …”
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48769
Table_1_CDT1 Is a Novel Prognostic and Predictive Biomarkers for Hepatocellular Carcinoma.docx
Published 2021“…CDT1 protein expression was evaluated by immunohistochemistry in HCC tissues through a tissue microarray. qRT-PCR, western blot and a cohort of functional experiments were performed for in vitro validation.…”
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48770
Table_4_Impacts of smoking on alcoholic liver disease: a nationwide cohort study.docx
Published 2024“…Objectives<p>Smoking is a preventable risk factor for morbidity and mortality in patients with liver disease. …”
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48771
Effect of sea cucumber supplementation on expression of genes involved in lipid metabolism, a schematic representation.
Published 2013“…Schematically, increased cellular cholesterol levels leads to decreased cholesterol biosynthesis through the 3-Hydroxy-3-methylglutaryl CoA reductase (HMGCR) pathway and increased cholesterol efflux through the ATP-binding cassette transporter A1 and G1(ABCA1, ABCG1). …”
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48772
pH-Lemon, a Fluorescent Protein-Based pH Reporter for Acidic Compartments
Published 2019“…Fusion of pH-Lemon to the protein microtubule-associated protein 1A/1B-light chain 3B (LC3B), a specific marker of autophagic membranes, resulted in its targeting within autolysosomes of HeLa cells. …”
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48773
Table1_Relationship between cathepsins and cardiovascular diseases: a Mendelian randomized study.xlsx
Published 2024“…Recent studies suggest a potential link between cathepsins and CVDs, yet the exact causal relationship remains to be elucidated. …”
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48774
Cardiovascular autonomic modulation and baroreflex control in the second trimester of pregnancy: A cross sectional study
Published 2019“…</p><p>Trial registration</p><p>Begistro Brasileiro de Ensaios clínicos, Number: <a href="http://www.ensaiosclinicos.gov.br/rg/RBR-9s8t88/" target="_blank">RBR-9s8t88</a>.…”
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48775
Table_2_Genotypes of Pain and Analgesia in a Randomized Trial of Irritable Bowel Syndrome.XLSX
Published 2022“…Background<p>Irritable bowel syndrome (IBS) is a highly prevalent chronic pain disorder with multiple underlying mechanisms and few treatments that have been demonstrated to be effective in placebo controlled trials. …”
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48776
Indoor Social Networks in a South African Township: Potential Contribution of Location to Tuberculosis Transmission
Published 2012“…We therefore quantified time spent and contacts met in indoor locations and public transport by residents of a South African township with a very high TB burden.…”
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48777
Effect of Three Interventions on Contact Lens Comfort in Symptomatic Wearers: A Randomized Clinical Trial
Published 2015“…Five hours after lens application, one of the following three interventions or a control was performed on each eye: replacing the existing lens with a new lens; removing and reapplying the same lens; performing a ‘scleral swish’; and no action (control). …”
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48778
Table_2_Impacts of smoking on alcoholic liver disease: a nationwide cohort study.docx
Published 2024“…Objectives<p>Smoking is a preventable risk factor for morbidity and mortality in patients with liver disease. …”
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48779
Data_Sheet_1_Modulation of gut microbiota: The effects of a fruits and vegetables supplement.PDF
Published 2022“…The gut microbiome composition, measured by 16S rDNA sequencing, showed no difference in both alpha and beta diversities, whereas the LEfse analysis revealed a microbial shift after the treatment, with a decreased abundance of the genus Ruminococcus from the Lachnospiraceae family (p = 0.009), and the unclassified genus from the family Erysipelotrichaceae (UC36, p = 0.003) in the FVS group compared with the PLA group (confirmed by SIAMCAT analysis, AUC = 74.1%). …”
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48780
Phase 1 Study of a Sulforaphane-Containing Broccoli Sprout Homogenate for Sickle Cell Disease
Published 2016“…To test this hypothesis, we performed a Phase 1, open-label, dose-escalation study of SFN, contained in a broccoli sprout homogenate (BSH) that naturally contains SFN, in adults with SCD. …”